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pLKO.3G Citations (31)

Originally described in: pLKO variants

Articles Citing pLKO.3G

In vivo genetic manipulation of the rat trophoblast cell lineage using lentiviral vector delivery. Lee DS, Rumi MA, Konno T, Soares MJ. Genesis. 2009 Jul;47(7):433-9. doi: 10.1002/dvg.20518. PubMed
Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion. Xue B, Krishnamurthy K, Allred DC, Muthuswamy SK. Nat Cell Biol. 2013 Feb;15(2):189-200. doi: 10.1038/ncb2663. Epub 2012 Dec 23. PubMed
EED and KDM6B coordinate the first mammalian cell lineage commitment to ensure embryo implantation. Saha B, Home P, Ray S, Larson M, Paul A, Rajendran G, Behr B, Paul S. Mol Cell Biol. 2013 Jul;33(14):2691-705. doi: 10.1128/MCB.00069-13. Epub 2013 May 13. PubMed
Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells. Zhang X, Weissman SM, Newburger PE. RNA Biol. 2014;11(6):777-87. Epub 2014 Apr 24. PubMed
Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells. Jang J, Wang Y, Kim HS, Lalli MA, Kosik KS. Stem Cells. 2014 Oct;32(10):2616-25. doi: 10.1002/stem.1764. PubMed
LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues. Chan KT, Asokan SB, King SJ, Bo T, Dubose ES, Liu W, Berginski ME, Simon JM, Davis IJ, Gomez SM, Sharpless NE, Bear JE. J Cell Biol. 2014 Oct 27;207(2):299-315. doi: 10.1083/jcb.201404067. PubMed
Regulation of RAB5C is important for the growth inhibitory effects of MiR-509 in human precursor-B acute lymphoblastic leukemia. Tan YS, Kim M, Kingsbury TJ, Civin CI, Cheng WC. PLoS One. 2014 Nov 4;9(11):e111777. doi: 10.1371/journal.pone.0111777. eCollection 2014. PubMed
Epstein-Barr Virus Modulates Host Cell MicroRNA-194 to Promote IL-10 Production and B Lymphoma Cell Survival. Harris-Arnold A, Arnold CP, Schaffert S, Hatton O, Krams SM, Esquivel CO, Martinez OM. Am J Transplant. 2015 Jul 3. doi: 10.1111/ajt.13375. PubMed
OVO-like 1 regulates progenitor cell fate in human trophoblast development. Renaud SJ, Chakraborty D, Mason CW, Rumi MA, Vivian JL, Soares MJ. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6175-84. doi: 10.1073/pnas.1507397112. Epub 2015 Oct 26. PubMed
Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms. Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Ohsaka A, Komatsu N. Blood. 2016 Jan 27. pii: blood-2015-09-671172. PubMed

Associated Plasmids

Genetic redundancy of GATA factors in the extraembryonic trophoblast lineage ensures the progression of preimplantation and postimplantation mammalian development. Home P, Kumar RP, Ganguly A, Saha B, Milano-Foster J, Bhattacharya B, Ray S, Gunewardena S, Paul A, Camper SA, Fields PE, Paul S. Development. 2017 Mar 1;144(5):876-888. doi: 10.1242/dev.145318. PubMed
A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic beta-Cells. Buenaventura T, Kanda N, Douzenis PC, Jones B, Bloom SR, Chabosseau P, Correa IR Jr., Bosco D, Piemonti L, Marchetti P, Johnson PR, Shapiro AMJ, Rutter GA, Tomas A. Diabetes. 2018 Mar;67(3):385-399. doi: 10.2337/db17-0639. Epub 2017 Dec 28. PubMed
Targeting GLP-1 receptor trafficking to improve agonist efficacy. Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen BM, Scott R, Goldin R, Angkathunyakul N, Correa IR Jr, Bosco D, Johnson PR, Piemonti L, Marchetti P, Shapiro AMJ, Cochran BJ, Hanyaloglu AC, Inoue A, Tan T, Rutter GA, Tomas A, Bloom SR. Nat Commun. 2018 Apr 23;9(1):1602. doi: 10.1038/s41467-018-03941-2. PubMed
The splicing factor RBM25 controls MYC activity in acute myeloid leukemia. Ge Y, Schuster MB, Pundhir S, Rapin N, Bagger FO, Sidiropoulos N, Hashem N, Porse BT. Nat Commun. 2019 Jan 11;10(1):172. doi: 10.1038/s41467-018-08076-y. PubMed
Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Aho ER, Wang J, Gogliotti RD, Howard GC, Phan J, Acharya P, Macdonald JD, Cheng K, Lorey SL, Lu B, Wenzel S, Foshage AM, Alvarado J, Wang F, Shaw JG, Zhao B, Weissmiller AM, Thomas LR, Vakoc CR, Hall MD, Hiebert SW, Liu Q, Stauffer SR, Fesik SW, Tansey WP. Cell Rep. 2019 Mar 12;26(11):2916-2928.e13. doi: 10.1016/j.celrep.2019.02.047. PubMed
Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties. Kong X, Chen J, Xie W, Brown SM, Cai Y, Wu K, Fan D, Nie Y, Yegnasubramanian S, Tiedemann RL, Tao Y, Chiu Yen RW, Topper MJ, Zahnow CA, Easwaran H, Rothbart SB, Xia L, Baylin SB. Cancer Cell. 2019 Apr 15;35(4):633-648.e7. doi: 10.1016/j.ccell.2019.03.003. Epub 2019 Apr 4. PubMed
Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells. Tay RE, Olawoyin O, Cejas P, Xie Y, Meyer CA, Weng QY, Fisher DE, Long HW, Brown M, Kim HJ, Wucherpfennig KW. J Exp Med. 2020 Jul 6;217(7). pii: 151741. doi: 10.1084/jem.20191453. PubMed
CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells. Kumar S, Zeng Z, Bagati A, Tay RE, Sanz LA, Hartono SR, Ito Y, Abderazzaq F, Hatchi E, Jiang P, Cartwright ANR, Olawoyin O, Mathewson ND, Pyrdol JW, Li MZ, Doench JG, Booker MA, Tolstorukov MY, Elledge SJ, Chedin F, Liu XS, Wucherpfennig KW. Cancer Discov. 2021 Aug;11(8):2050-2071. doi: 10.1158/2159-8290.CD-20-1144. Epub 2021 Mar 11. PubMed
Histone chaperone CAF-1 promotes HIV-1 latency by leading the formation of phase-separated suppressive nuclear bodies. Ma X, Chen T, Peng Z, Wang Z, Liu J, Yang T, Wu L, Liu G, Zhou M, Tong M, Guan Y, Zhang X, Lin Y, Tang X, Li L, Tang Z, Pan T, Zhang H. EMBO J. 2021 May 17;40(10):e106632. doi: 10.15252/embj.2020106632. Epub 2021 Mar 19. PubMed
Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity. Langdon CG, Gadek KE, Garcia MR, Evans MK, Reed KB, Bush M, Hanna JA, Drummond CJ, Maguire MC, Leavey PJ, Finkelstein D, Jin H, Schreiner PA, Rehg JE, Hatley ME. Nat Commun. 2021 Sep 17;12(1):5520. doi: 10.1038/s41467-021-25829-4. PubMed
A Novel ZNF304/miR-183-5p/FOXO4 Pathway Regulates Cell Proliferation in Clear Cell Renal Carcinoma. Ren LX, Zeng BW, Zhu M, Zhao AN, Shi B, Zhang H, Wang DD, Gu JF, Yang Z. Front Oncol. 2021 Oct 7;11:710525. doi: 10.3389/fonc.2021.710525. eCollection 2021. PubMed
Ablation of T cell-associated PD-1H enhances functionality and promotes adoptive immunotherapy. Hu L, Chen L, Xiao Z, Zheng X, Chen Y, Xian N, Cho C, Luo L, Huang G, Chen L. JCI Insight. 2022 Jan 25;7(2). pii: 148247. doi: 10.1172/jci.insight.148247. PubMed
Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium. Padonou F, Gonzalez V, Provin N, Yayilkan S, Jmari N, Maslovskaja J, Kisand K, Peterson P, Irla M, Giraud M. EMBO Rep. 2022 Feb 3;23(3):e53576. doi: 10.15252/embr.202153576. Epub 2022 Jan 17. PubMed
Acquired chemoresistance drives spatial heterogeneity, chemoprotection and collective migration in pancreatic tumor spheroids. Thege FI, Cardle II, Gruber CN, Siemann MJ, Cong S, Wittmann K, Love J, Kirby BJ. PLoS One. 2022 May 26;17(5):e0267882. doi: 10.1371/journal.pone.0267882. eCollection 2022. PubMed
Differential cofactor dependencies define distinct types of human enhancers. Neumayr C, Haberle V, Serebreni L, Karner K, Hendy O, Boija A, Henninger JE, Li CH, Stejskal K, Lin G, Bergauer K, Pagani M, Rath M, Mechtler K, Arnold CD, Stark A. Nature. 2022 Jun;606(7913):406-413. doi: 10.1038/s41586-022-04779-x. Epub 2022 Jun 1. PubMed
Genome-scale CRISPR-Cas9 screen reveals novel regulators of B7-H3 in tumor cells. Zhao S, Wang Y, Yang N, Mu M, Wu Z, Li H, Tang X, Zhong K, Zhang Z, Huang C, Cao T, Zheng M, Wang G, Nie C, Yang H, Guo G, Zhou L, Zheng X, Tong A. J Immunother Cancer. 2022 Jun;10(6). pii: jitc-2022-004875. doi: 10.1136/jitc-2022-004875. PubMed
Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice. Qiao H, Tian Y, Huo Y, Man HY. iScience. 2022 Jun 14;25(7):104595. doi: 10.1016/j.isci.2022.104595. eCollection 2022 Jul 15. PubMed
Sec22b is a critical and nonredundant regulator of plasma cell maintenance. Bonaud A, Gargowitsch L, Gilbert SM, Rajan E, Canales-Herrerias P, Stockholm D, Rahman NF, Collins MO, Taskiran H, Hill DL, Alloatti A, Alouche N, Balor S, Soldan V, Gillet D, Barbier J, Bachelerie F, Smith KGC, Jellusova J, Bruhns P, Amigorena S, Balabanian K, Linterman MA, Peden AA, Espeli M. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2213056120. doi: 10.1073/pnas.2213056120. Epub 2023 Jan 3. PubMed
miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy. Xylaki M, Paiva I, Al-Azzani M, Gerhardt E, Jain G, Islam MR, Vasili E, Wassouf Z, Schulze-Hentrich JM, Fischer A, Outeiro TF. J Parkinsons Dis. 2023;13(2):179-196. doi: 10.3233/JPD-225055. PubMed
STAC1 is required for glioblastoma cell invasion and survival. Yoon Y, Yoo CR, Kim EC, Han J, Yoon K. Biochem Biophys Res Commun. 2023 Sep 24;674:75-82. doi: 10.1016/j.bbrc.2023.06.089. Epub 2023 Jun 29. PubMed
PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors. Searcy MB, Larsen RK 4th, Stevens BT, Zhang Y, Jin H, Drummond CJ, Langdon CG, Gadek KE, Vuong K, Reed KB, Garcia MR, Xu B, Kimbrough DW, Adkins GE, Djekidel N, Porter SN, Schreiner PA, Pruett-Miller SM, Abraham BJ, Rehg JE, Hatley ME. Nat Commun. 2023 Nov 15;14(1):7291. doi: 10.1038/s41467-023-43044-1. PubMed

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