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pTriEx-mCherry-PA-Rac1 Citations (19)

Originally described in: A genetically encoded photoactivatable Rac controls the motility of living cells.
Wu YI, Frey D, Lungu OI, Jaehrig A, Schlichting I, Kuhlman B, Hahn KM Nature. 2009 Sep 3. 461(7260):104-8. PubMed Journal

Articles Citing pTriEx-mCherry-PA-Rac1

Articles
A synthetic photoactivated protein to generate local or global Ca(2+) signals. Pham E, Mills E, Truong K. Chem Biol. 2011 Jul 29;18(7):880-90. PubMed

Associated Plasmids
Actomyosin pulls to advance the nucleus in a migrating tissue cell. Wu J, Kent IA, Shekhar N, Chancellor TJ, Mendonca A, Dickinson RB, Lele TP. Biophys J. 2014 Jan 7;106(1):7-15. doi: 10.1016/j.bpj.2013.11.4489. PubMed
Inter-cellular exchange of cellular components via VE-cadherin-dependent trans-endocytosis. Sakurai T, Woolls MJ, Jin SW, Murakami M, Simons M. PLoS One. 2014 Mar 6;9(6):e90736. doi: 10.1371/journal.pone.0090736. eCollection 2014. PubMed
Rac1-dependent lamellipodial motility in prostate cancer PC-3 cells revealed by optogenetic control of Rac1 activity. Kato T, Kawai K, Egami Y, Kakehi Y, Araki N. PLoS One. 2014 May 21;9(5):e97749. doi: 10.1371/journal.pone.0097749. eCollection 2014. PubMed
An Engineered Split Intein for Photoactivated Protein Trans-Splicing. Wong S, Mosabbir AA, Truong K. PLoS One. 2015 Aug 28;10(8):e0135965. doi: 10.1371/journal.pone.0135965. eCollection 2015. PubMed
Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation. He L, Zhang Y, Ma G, Tan P, Li Z, Zang S, Wu X, Jing J, Fang S, Zhou L, Wang Y, Huang Y, Hogan PG, Han G, Zhou Y. Elife. 2015 Dec 8;4. pii: e10024. doi: 10.7554/eLife.10024. PubMed

Associated Plasmids
LOV2-Controlled Photoactivation of Protein Trans-Splicing. Qudrat A, Mosabbir A, Truong K. Methods Mol Biol. 2017;1495:227-237. PubMed
Rac1 switching at the right time and location is essential for Fcgamma receptor-mediated phagosome formation. Ikeda Y, Kawai K, Ikawa A, Kawamoto K, Egami Y, Araki N. J Cell Sci. 2017 Jun 9. pii: jcs.201749. doi: 10.1242/jcs.201749. PubMed
Fear Conditioning Downregulates Rac1 Activity in the Basolateral Amygdala Astrocytes to Facilitate the Formation of Fear Memory. Liao Z, Tao Y, Guo X, Cheng D, Wang F, Liu X, Ma L. Front Mol Neurosci. 2017 Nov 27;10:396. doi: 10.3389/fnmol.2017.00396. eCollection 2017. PubMed
Local control of intracellular microtubule dynamics by EB1 photodissociation. van Haren J, Charafeddine RA, Ettinger A, Wang H, Hahn KM, Wittmann T. Nat Cell Biol. 2018 Jan 29. pii: 10.1038/s41556-017-0028-5. doi: 10.1038/s41556-017-0028-5. PubMed

Associated Plasmids
Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation. Yang JM, Bhattacharya S, West-Foyle H, Hung CF, Wu TC, Iglesias PA, Huang CH. Nat Commun. 2018 Nov 7;9(1):4673. doi: 10.1038/s41467-018-07150-9. PubMed
Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation. Laufer JM, Hauser MA, Kindinger I, Purvanov V, Pauli A, Legler DF. Cell Rep. 2019 Oct 22;29(4):995-1009.e6. doi: 10.1016/j.celrep.2019.09.031. PubMed
Golgi-associated microtubules are fast cargo tracks and required for persistent cell migration. Hao H, Niu J, Xue B, Su QP, Liu M, Yang J, Qin J, Zhao S, Wu C, Sun Y. EMBO Rep. 2020 Mar 4;21(3):e48385. doi: 10.15252/embr.201948385. Epub 2020 Jan 27. PubMed
Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects. Harris JM, Wang AY, Boulanger-Weill J, Santoriello C, Foianini S, Lichtman JW, Zon LI, Arlotta P. Dev Cell. 2020 Jun 8;53(5):577-588.e7. doi: 10.1016/j.devcel.2020.05.009. PubMed

Associated Plasmids
The WAVE Regulatory Complex Is Required to Balance Protrusion and Adhesion in Migration. Whitelaw JA, Swaminathan K, Kage F, Machesky LM. Cells. 2020 Jul 7;9(7). pii: cells9071635. doi: 10.3390/cells9071635. PubMed
A novel DENND1B-localized structure found at the basal side of adherent cells. Park EW, Kawai K, Egami Y, Araki N. Histochem Cell Biol. 2021 Jan;155(1):9-18. doi: 10.1007/s00418-020-01935-0. Epub 2020 Nov 2. PubMed
Rac1 Signaling in Amygdala Astrocytes Regulates Fear Memory Acquisition and Retrieval. Fan XC, Ma CN, Song JC, Liao ZH, Huang N, Liu X, Ma L. Neurosci Bull. 2021 Jul;37(7):947-958. doi: 10.1007/s12264-021-00677-w. Epub 2021 Apr 28. PubMed
Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration. Arts JJ, Mahlandt EK, Gronloh ML, Schimmel L, Noordstra I, Gordon E, van Steen AC, Tol S, Walzog B, van Rijssel J, Nolte MA, Postma M, Khuon S, Heddleston JM, Wait E, Chew TL, Winter M, Montanez E, Goedhart J, van Buul JD. Elife. 2021 Aug 25;10. pii: 66074. doi: 10.7554/eLife.66074. PubMed
Non-muscle myosin II isoforms orchestrate substrate stiffness sensing to promote cancer cell contractility and migration. Peng Y, Chen Z, He Y, Li P, Chen Y, Chen X, Jiang Y, Qin X, Li S, Li T, Wu C, Yang H, You F, Liu Y. Cancer Lett. 2022 Jan 1;524:245-258. doi: 10.1016/j.canlet.2021.10.030. Epub 2021 Oct 27. PubMed

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