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YFP-Parkin Citations (26)

Plasmid Article: Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Narendra D, Tanaka A, Suen DF, Youle RJ J Cell Biol. 2008 Dec 1. 183(5):795-803.
PubMed Journal

Articles Citing YFP-Parkin

Spatiotemporally controlled initiation of Parkin-mediated mitophagy within single cells. Yang JY, Yang WY. Autophagy. 2011 Oct;7(10):1230-8. doi: 10.4161/auto.7.10.16626. PubMed
Mitochondrial dysfunction in ataxia-telangiectasia. Valentin-Vega YA, Maclean KH, Tait-Mulder J, Milasta S, Steeves M, Dorsey FC, Cleveland JL, Green DR, Kastan MB. Blood. 2012 Feb 9;119(6):1490-500. doi: 10.1182/blood-2011-08-373639. Epub 2011 Dec 5. PubMed
Mesenchymal bone marrow stem cells within polyglycolic acid tube observed in vivo after six weeks enhance facial nerve regeneration. Costa HJ, Ferreira Bento R, Salomone R, Azzi-Nogueira D, Zanatta DB, Paulino Costa M, da Silva CF, Strauss BE, Haddad LA. Brain Res. 2013 May 13;1510:10-21. doi: 10.1016/j.brainres.2013.03.025. Epub 2013 Mar 28. PubMed
Bit-by-bit autophagic removal of parkin-labelled mitochondria. Yang JY, Yang WY. Nat Commun. 2013;4:2428. doi: 10.1038/ncomms3428. PubMed
The protonophore CCCP interferes with lysosomal degradation of autophagic cargo in yeast and mammalian cells. Padman BS, Bach M, Lucarelli G, Prescott M, Ramm G. Autophagy. 2013 Nov 1;9(11):1862-75. doi: 10.4161/auto.26557. Epub 2013 Sep 27. PubMed
Identification of the ubiquitin-like domain of midnolin as a new glucokinase interaction partner. Hofmeister-Brix A, Kollmann K, Langer S, Schultz J, Lenzen S, Baltrusch S. J Biol Chem. 2013 Dec 13;288(50):35824-39. doi: 10.1074/jbc.M113.526632. Epub 2013 Nov 1. PubMed
HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle. Drew BG, Ribas V, Le JA, Henstridge DC, Phun J, Zhou Z, Soleymani T, Daraei P, Sitz D, Vergnes L, Wanagat J, Reue K, Febbraio MA, Hevener AL. Diabetes. 2014 May;63(5):1488-505. doi: 10.2337/db13-0665. Epub 2013 Dec 30. PubMed
Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase. Birsa N, Norkett R, Wauer T, Mevissen TE, Wu HC, Foltynie T, Bhatia K, Hirst WD, Komander D, Plun-Favreau H, Kittler JT. J Biol Chem. 2014 May 23;289(21):14569-82. doi: 10.1074/jbc.M114.563031. Epub 2014 Mar 26. PubMed

Associated Plasmids

Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria. Di Sante G, Pestell TG, Casimiro MC, Bisetto S, Powell MJ, Lisanti MP, Cordon-Cardo C, Castillo-Martin M, Bonal DM, Debattisti V, Chen K, Wang L, He X, McBurney MW, Pestell RG. Am J Pathol. 2015 Jan;185(1):266-79. doi: 10.1016/j.ajpath.2014.09.014. PubMed
Triggering mitophagy with far-red fluorescent photosensitizers. Hsieh CW, Chu CH, Lee HM, Yuan Yang W. Sci Rep. 2015 May 29;5:10376. doi: 10.1038/srep10376. PubMed
Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids. Swiader A, Nahapetyan H, Faccini J, D'Angelo R, Mucher E, Elbaz M, Boya P, Vindis C. Oncotarget. 2016 May 17;7(20):28821-35. doi: 10.18632/oncotarget.8936. PubMed
Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin. Scott TL, Wicker CA, Suganya R, Dhar B, Pittman T, Horbinski C, Izumi T. Mol Carcinog. 2016 May 5. doi: 10.1002/mc.22495. PubMed
Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy. Di Sante G, Casimiro MC, Pestell TG, Pestell RG. J Vis Exp. 2016 May 4;(111). doi: 10.3791/53657. PubMed
Absence of the Autophagy Adaptor SQSTM1/p62 Causes Childhood-Onset Neurodegeneration with Ataxia, Dystonia, and Gaze Palsy. Haack TB, Ignatius E, Calvo-Garrido J, Iuso A, Isohanni P, Maffezzini C, Lonnqvist T, Suomalainen A, Gorza M, Kremer LS, Graf E, Hartig M, Berutti R, Paucar M, Svenningsson P, Stranneheim H, Brandberg G, Wedell A, Kurian MA, Hayflick SA, Venco P, Tiranti V, Strom TM, Dichgans M, Horvath R, Holinski-Feder E, Freyer C, Meitinger T, Prokisch H, Senderek J, Wredenberg A, Carroll CJ, Klopstock T. Am J Hum Genet. 2016 Sep 1;99(3):735-743. doi: 10.1016/j.ajhg.2016.06.026. Epub 2016 Aug 18. PubMed
Parkin elimination of mitochondria is important for maintenance of lens epithelial cell ROS levels and survival upon oxidative stress exposure. Brennan L, Khoury J, Kantorow M. Biochim Biophys Acta. 2017 Jan;1863(1):21-32. doi: 10.1016/j.bbadis.2016.09.020. Epub 2016 Oct 1. PubMed
A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Hammerling BC, Najor RH, Cortez MQ, Shires SE, Leon LJ, Gonzalez ER, Boassa D, Phan S, Thor A, Jimenez RE, Li H, Kitsis RN, Dorn Ii GW, Sadoshima J, Ellisman MH, Gustafsson AB. Nat Commun. 2017 Jan 30;8:14050. doi: 10.1038/ncomms14050. PubMed
RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome. Zhang Y, Su SS, Zhao S, Yang Z, Zhong CQ, Chen X, Cai Q, Yang ZH, Huang D, Wu R, Han J. Nat Commun. 2017 Feb 8;8:14329. doi: 10.1038/ncomms14329. PubMed
Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy. Zhang Y, Nguyen DT, Olzomer EM, Poon GP, Cole NJ, Puvanendran A, Phillips BR, Hesselson D. Cell Chem Biol. 2017 Apr 20;24(4):471-480.e4. doi: 10.1016/j.chembiol.2017.03.005. Epub 2017 Mar 30. PubMed
Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes. Ansari MY, Khan NM, Ahmad I, Haqqi TM. Osteoarthritis Cartilage. 2017 Aug 8. pii: S1063-4584(17)31125-1. doi: 10.1016/j.joca.2017.07.020. PubMed
Lead (Pb) induced ATM-dependent mitophagy via PINK1/Parkin pathway. Gu X, Qi Y, Feng Z, Ma L, Gao K, Zhang Y. Toxicol Lett. 2018 Jul;291:92-100. doi: 10.1016/j.toxlet.2018.04.012. Epub 2018 Apr 13. PubMed
Parkin is a disease modifier in the mutant SOD1 mouse model of ALS. Palomo GM, Granatiero V, Kawamata H, Konrad C, Kim M, Arreguin AJ, Zhao D, Milner TA, Manfredi G. EMBO Mol Med. 2018 Oct;10(10). pii: emmm.201808888. doi: 10.15252/emmm.201808888. PubMed
Extracellular Collagen VI Has Prosurvival and Autophagy Instructive Properties in Mouse Fibroblasts. Castagnaro S, Chrisam M, Cescon M, Braghetta P, Grumati P, Bonaldo P. Front Physiol. 2018 Aug 17;9:1129. doi: 10.3389/fphys.2018.01129. eCollection 2018. PubMed
Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy. Sun X, Duan Y, Qin C, Li JC, Duan G, Deng X, Ni J, Cao X, Xiang K, Tian K, Chen CH, Li A, Fang Y. Cell Death Dis. 2018 Sep 20;9(10):953. doi: 10.1038/s41419-018-1022-y. PubMed
Omegasome-proximal PtdIns(4,5)P2 couples F-actin mediated mitoaggregate disassembly with autophagosome formation during mitophagy. Hsieh CW, Yang WY. Nat Commun. 2019 Feb 27;10(1):969. doi: 10.1038/s41467-019-08924-5. PubMed
Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis. Gunn TM, Silvius D, Lester A, Gibbs B. Mamm Genome. 2019 Jun;30(5-6):151-165. doi: 10.1007/s00335-019-09802-7. Epub 2019 May 14. PubMed
Activation of PINK1-Parkin-Mediated Mitophagy Degrades Mitochondrial Quality Control Proteins in Fuchs Endothelial Corneal Dystrophy. Miyai T, Vasanth S, Melangath G, Deshpande N, Kumar V, Benischke AS, Chen Y, Price MO, Price FW Jr, Jurkunas UV. Am J Pathol. 2019 Oct;189(10):2061-2076. doi: 10.1016/j.ajpath.2019.06.012. Epub 2019 Jul 27. PubMed

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