Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

pEGFP-Q23 Citations (10)

Plasmid Article: A molecular investigation of true dominance in Huntington's disease.
Narain Y, Wyttenbach A, Rankin J, Furlong RA, Rubinsztein DC J Med Genet. 1999 Oct;36(10):739-46.
PubMed Journal

Articles Citing pEGFP-Q23

HDAC6 inhibition induces mitochondrial fusion, autophagic flux and reduces diffuse mutant huntingtin in striatal neurons. Guedes-Dias P, de Proenca J, Soares TR, Leitao-Rocha A, Pinho BR, Duchen MR, Oliveira JM. Biochim Biophys Acta. 2015 Nov;1852(11):2484-93. doi: 10.1016/j.bbadis.2015.08.012. Epub 2015 Aug 21. PubMed
The Social Amoeba Dictyostelium discoideum Is Highly Resistant to Polyglutamine Aggregation. Santarriaga S, Petersen A, Ndukwe K, Brandt A, Gerges N, Bruns Scaglione J, Scaglione KM. J Biol Chem. 2015 Oct 16;290(42):25571-8. doi: 10.1074/jbc.M115.676247. Epub 2015 Sep 1. PubMed
A Method for the Acute and Rapid Degradation of Endogenous Proteins. Clift D, McEwan WA, Labzin LI, Konieczny V, Mogessie B, James LC, Schuh M. Cell. 2017 Nov 13. pii: S0092-8674(17)31255-2. doi: 10.1016/j.cell.2017.10.033. PubMed

Associated Plasmids

Inhibition of PIP4Kgamma ameliorates the pathological effects of mutant huntingtin protein. Al-Ramahi I, Panapakkam Giridharan SS, Chen YC, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, Ferrer M, Southall N, Weisman LS, Botas J, Marugan JJ. Elife. 2017 Dec 26;6. pii: 29123. doi: 10.7554/eLife.29123. PubMed
Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C, Huh CJ, Zhang B, Davidson BL, Yang XW, Yoo AS. Nat Neurosci. 2018 Mar;21(3):341-352. doi: 10.1038/s41593-018-0075-7. Epub 2018 Feb 5. PubMed
A Split Transcriptional Repressor That Links Protein Solubility to an Orthogonal Genetic Circuit. Zeng Y, Jones AM, Thomas EE, Nassif B, Silberg JJ, Segatori L. ACS Synth Biol. 2018 Sep 21;7(9):2126-2138. doi: 10.1021/acssynbio.8b00129. Epub 2018 Aug 23. PubMed
Heat shock promotes inclusion body formation of mutant huntingtin (mHtt) and alleviates mHtt-induced transcription factor dysfunction. Chen JY, Parekh M, Seliman H, Bakshinskaya D, Dai W, Kwan K, Chen KY, Liu AYC. J Biol Chem. 2018 Oct 5;293(40):15581-15593. doi: 10.1074/jbc.RA118.002933. Epub 2018 Aug 24. PubMed
GLP-1 Analogue Liraglutide Attenuates Mutant Huntingtin-Induced Neurotoxicity by Restoration of Neuronal Insulin Signaling. Chang CC, Lin TC, Ho HL, Kuo CY, Li HH, Korolenko TA, Chen WJ, Lai TJ, Ho YJ, Lin CL. Int J Mol Sci. 2018 Aug 24;19(9). pii: ijms19092505. doi: 10.3390/ijms19092505. PubMed
Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells. Pinho BR, Reis SD, Hartley RC, Murphy MP, Oliveira JMA. Free Radic Biol Med. 2019 Jan;130:318-327. doi: 10.1016/j.freeradbiomed.2018.10.446. Epub 2018 Oct 31. PubMed
The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity. Echeverria PC, Bhattacharya K, Joshi A, Wang T, Picard D. PLoS One. 2019 Feb 6;14(2):e0208287. doi: 10.1371/journal.pone.0208287. eCollection 2019. PubMed

If you have published an article using this plasmid, please email us at [email protected] to have your article added to this page.