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AAVS1-Neo-M2rtTA Citations (12)

Originally described in: Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.
DeKelver RC, Choi VM, Moehle EA, Paschon DE, Hockemeyer D, Meijsing SH, Sancak Y, Cui X, Steine EJ, Miller JC, Tam P, Bartsevich VV, Meng X, Rupniewski I, Gopalan SM, Sun HC, Pitz KJ, Rock JM, Zhang L, Davis GD, Rebar EJ, Cheeseman IM, Yamamoto KR, Sabatini DM, Jaenisch R, Gregory PD, Urnov FD Genome Res. 2010 Aug;20(8):1133-42. doi: 10.1101/gr.106773.110. Epub 2010 May 27. PubMed Journal

Articles Citing AAVS1-Neo-M2rtTA

Articles
Application of CRISPR/Cas9 to Autophagy Research. O'Prey J, Sakamaki J, Baudot AD, New M, Van Acker T, Tooze SA, Long JS, Ryan KM. Methods Enzymol. 2017;588:79-108. doi: 10.1016/bs.mie.2016.09.076. Epub 2016 Dec 1. PubMed
Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the "safe harbor" AAVS1 locus. Castano J, Bueno C, Jimenez-Delgado S, Roca-Ho H, Fraga MF, Fernandez AF, Nakanishi M, Torres-Ruiz R, Rodriguez-Perales S, Menendez P. Stem Cell Res. 2017 May;21:137-140. doi: 10.1016/j.scr.2017.04.011. Epub 2017 Apr 22. PubMed

Associated Plasmids
Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal. Ferreccio A, Mathieu J, Detraux D, Somasundaram L, Cavanaugh C, Sopher B, Fischer K, Bello T, M Hussein A, Levy S, Cook S, Sidhu SB, Artoni F, Palpant NJ, Reinecke H, Wang Y, Paddison P, Murry C, Jayadev S, Ware C, Ruohola-Baker H. Cell Cycle. 2018;17(5):535-549. doi: 10.1080/15384101.2018.1442621. Epub 2018 Apr 5. PubMed
Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system. Wu M, Liu S, Gao Y, Bai H, Machairaki V, Li G, Chen T, Cheng L. Stem Cell Res. 2018 May;29:6-14. doi: 10.1016/j.scr.2018.03.003. Epub 2018 Mar 10. PubMed

Associated Plasmids
Gene signatures of quiescent glioblastoma cells reveal mesenchymal shift and interactions with niche microenvironment. Tejero R, Huang Y, Katsyv I, Kluge M, Lin JY, Tome-Garcia J, Daviaud N, Wang Y, Zhang B, Tsankova NM, Friedel CC, Zou H, Friedel RH. EBioMedicine. 2019 Apr 2. pii: S2352-3964(19)30209-9. doi: 10.1016/j.ebiom.2019.03.064. PubMed

Associated Plasmids
A Platform for Studying Neurodegeneration Mechanisms Using Genetically Encoded Biosensors. Ustyantseva EI, Medvedev SP, Vetchinova AS, Minina JM, Illarioshkin SN, Zakian SM. Biochemistry (Mosc). 2019 Mar;84(3):299-309. doi: 10.1134/S000629791903012X. PubMed
Loss of the transcription factor MAFB limits beta-cell derivation from human PSCs. Russell R, Carnese PP, Hennings TG, Walker EM, Russ HA, Liu JS, Giacometti S, Stein R, Hebrok M. Nat Commun. 2020 Jun 2;11(1):2742. doi: 10.1038/s41467-020-16550-9. PubMed
Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus. Schmid B, Holst B, Poulsen U, Jorring I, Clausen C, Rasmussen M, Mau-Holzmann UA, Steeg R, Nuthall H, Ebneth A, Cabrera-Socorro A. Stem Cell Res. 2021 Apr;52:102240. doi: 10.1016/j.scr.2021.102240. Epub 2021 Feb 11. PubMed
Protocol for genome-scale CRISPR screening in engineered lineage reporter hPSCs to study cell fate determination. Zhou Z, Ma L, Zhang X. STAR Protoc. 2021 May 20;2(2):100548. doi: 10.1016/j.xpro.2021.100548. eCollection 2021 Jun 18. PubMed
Generation of Transgenic Rat Embryonic Stem Cells Using the CRISPR/Cpf1 System for Inducible Gene Knockout. Sherstyuk VV, Zakian SM. Biochemistry (Mosc). 2021 Jul;86(7):843-851. doi: 10.1134/S0006297921070051. PubMed
Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T alpha-synuclein levels and aggregation. Vajhoj C, Schmid B, Alik A, Melki R, Fog K, Holst B, Stummann TC. PLoS One. 2021 Dec 21;16(12):e0261536. doi: 10.1371/journal.pone.0261536. eCollection 2021. PubMed
Oxidative stress monitoring in iPSC-derived motor neurons using genetically encoded biosensors of H2O2. Ustyantseva E, Pavlova SV, Malakhova AA, Ustyantsev K, Zakian SM, Medvedev SP. Sci Rep. 2022 May 27;12(1):8928. doi: 10.1038/s41598-022-12807-z. PubMed

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