pmCherry-Gal3 Citations (14)
Originally described in: VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.Papadopoulos C, Kirchner P, Bug M, Grum D, Koerver L, Schulze N, Poehler R, Dressler A, Fengler S, Arhzaouy K, Lux V, Ehrmann M, Weihl CC, Meyer H EMBO J. 2016 Oct 17. pii: e201695148. PubMed Journal
Articles Citing pmCherry-Gal3
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Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol. Polanco JC, Hand GR, Briner A, Li C, Gotz J. Acta Neuropathol. 2021 Feb;141(2):235-256. doi: 10.1007/s00401-020-02254-3. Epub 2021 Jan 8. PubMed |
FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation. Hu P, Wang J, Qing Y, Li H, Sun W, Yu X, Hui H, Guo Q, Xu J. Cell Death Dis. 2021 Jan 13;12(1):80. doi: 10.1038/s41419-021-03394-4. PubMed |
Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death. Meyer N, Henkel L, Linder B, Zielke S, Tascher G, Trautmann S, Geisslinger G, Munch C, Fulda S, Tegeder I, Kogel D. Autophagy. 2021 Nov;17(11):3424-3443. doi: 10.1080/15548627.2021.1874208. Epub 2021 Jan 19. PubMed |
Restructuring of the plasma membrane upon damage by LC3-associated macropinocytosis. Sonder SL, Hager SC, Heitmann ASB, Frankel LB, Dias C, Simonsen AC, Nylandsted J. Sci Adv. 2021 Jul 2;7(27). pii: 7/27/eabg1969. doi: 10.1126/sciadv.abg1969. Print 2021 Jul. PubMed |
Rabaptin5 targets autophagy to damaged endosomes and Salmonella vacuoles via FIP200 and ATG16L1. Millarte V, Schlienger S, Kalin S, Spiess M. EMBO Rep. 2022 Jan 5;23(1):e53429. doi: 10.15252/embr.202153429. Epub 2021 Oct 26. PubMed |
Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218. Hu P, Li H, Sun W, Wang H, Yu X, Qing Y, Wang Z, Zhu M, Xu J, Guo Q, Hui H. Acta Pharm Sin B. 2021 Oct;11(10):3178-3192. doi: 10.1016/j.apsb.2021.02.004. Epub 2021 Feb 11. PubMed |
STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death. Remy J, Linder B, Weirauch U, Day BW, Stringer BW, Herold-Mende C, Aigner A, Krohn K, Kogel D. Cancers (Basel). 2022 Jan 11;14(2). pii: cancers14020339. doi: 10.3390/cancers14020339. PubMed |
PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805. Bai Y, Yu G, Zhou HM, Amarasinghe O, Zhou Y, Zhu P, Li Q, Zhang L, Nguele Meke F, Miao Y, Chapman E, Tao WA, Zhang ZY. Autophagy. 2023 May;19(5):1562-1581. doi: 10.1080/15548627.2022.2140558. Epub 2022 Nov 7. PubMed |
Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature. Rodrigues Lopes I, Alcantara LM, Silva RJ, Josse J, Vega EP, Cabrerizo AM, Bonhomme M, Lopez D, Laurent F, Vandenesch F, Mano M, Eulalio A. Nat Commun. 2022 Nov 22;13(1):7174. doi: 10.1038/s41467-022-34790-9. PubMed |
In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux. Hao M, Lu P, Sotropa S, Manupati K, Yeo SK, Guan JL. Cell Rep. 2024 Feb 27;43(2):113780. doi: 10.1016/j.celrep.2024.113780. Epub 2024 Feb 15. PubMed |
Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH.
Gahlot P, Kravic B, Rota G, van den Boom J, Levantovsky S, Schulze N, Maspero E, Polo S, Behrends C, Meyer H.
Mol Cell. 2024 Mar 14:S1097-2765(24)00172-2. doi: 10.1016/j.molcel.2024.02.029.
PubMed
Associated Plasmids |
Connexin43 promotes exocytosis of damaged lysosomes through actin remodelling. Domingues N, Catarino S, Cristovao B, Rodrigues L, Carvalho FA, Sarmento MJ, Zuzarte M, Almeida J, Ribeiro-Rodrigues T, Correia-Rodrigues A, Fernandes F, Rodrigues-Santos P, Aasen T, Santos NC, Korolchuk VI, Goncalves T, Milosevic I, Raimundo N, Girao H. EMBO J. 2024 Sep;43(17):3627-3649. doi: 10.1038/s44318-024-00177-3. Epub 2024 Jul 23. PubMed |
Dysregulation of protein degradation and alteration of secretome in alpha-synuclein-exposed astrocytes: implications for dopaminergic neuronal dysfunction. Raj A, Banerjee R, Holla V, Kamble N, Yadav R, Pal PK, Datta I. Cell Commun Signal. 2024 Dec 2;22(1):574. doi: 10.1186/s12964-024-01928-9. PubMed |
Activation of lysophagy by a TBK1-SCF(FBXO3)-TMEM192-TAX1BP1 axis in response to lysosomal damage. Park NY, Jo DS, Yang JY, Bae JE, Kim JB, Kim YH, Kim SH, Kim P, Lee DS, Yoshimori T, Jo EK, Yeom E, Cho DH. Nat Commun. 2025 Jan 28;16(1):1109. doi: 10.1038/s41467-025-56294-y. PubMed |
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