pCRIS-PITChv2-BSD-dTAG (BRD4) Citations (19)
Originally described in: The dTAG system for immediate and target-specific protein degradation.Nabet B, Roberts JM, Buckley DL, Paulk J, Dastjerdi S, Yang A, Leggett AL, Erb MA, Lawlor MA, Souza A, Scott TG, Vittori S, Perry JA, Qi J, Winter GE, Wong KK, Gray NS, Bradner JE Nat Chem Biol. 2018 May;14(5):431-441. doi: 10.1038/s41589-018-0021-8. Epub 2018 Mar 26. PubMed Journal
Articles Citing pCRIS-PITChv2-BSD-dTAG (BRD4)
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| Locus-Specific Knock-In of a Degradable Tag for Target Validation Studies. Brand M, Winter GE. Methods Mol Biol. 2019;1953:105-119. doi: 10.1007/978-1-4939-9145-7_7. PubMed |
| Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis. Bensimon A, Pizzagalli MD, Kartnig F, Dvorak V, Essletzbichler P, Winter GE, Superti-Furga G. Cell Chem Biol. 2020 Jun 18;27(6):728-739.e9. doi: 10.1016/j.chembiol.2020.04.003. Epub 2020 May 7. PubMed |
| Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis. Radzisheuskaya A, Shliaha PV, Grinev VV, Shlyueva D, Damhofer H, Koche R, Gorshkov V, Kovalchuk S, Zhan Y, Rodriguez KL, Johnstone AL, Keogh MC, Hendrickson RC, Jensen ON, Helin K. Mol Cell. 2021 Apr 15;81(8):1749-1765.e8. doi: 10.1016/j.molcel.2021.02.012. Epub 2021 Mar 2. PubMed |
Generation of locus-specific degradable tag knock-ins in mouse and human cell lines.
Damhofer H, Radzisheuskaya A, Helin K.
STAR Protoc. 2021 Jun 2;2(2):100575. doi: 10.1016/j.xpro.2021.100575. eCollection 2021 Jun 18.
PubMed
Associated Plasmids |
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation.
Lee JH, Wang R, Xiong F, Krakowiak J, Liao Z, Nguyen PT, Moroz-Omori EV, Shao J, Zhu X, Bolt MJ, Wu H, Singh PK, Bi M, Shi CJ, Jamal N, Li G, Mistry R, Jung SY, Tsai KL, Ferreon JC, Stossi F, Caflisch A, Liu Z, Mancini MA, Li W.
Mol Cell. 2021 Aug 19;81(16):3368-3385.e9. doi: 10.1016/j.molcel.2021.07.024. Epub 2021 Aug 9.
PubMed
Associated Plasmids |
| A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency. Huang X, Bashkenova N, Hong Y, Lyu C, Guallar D, Hu Z, Malik V, Li D, Wang H, Shen X, Zhou H, Wang J. Cell Rep. 2022 Jun 7;39(10):110928. doi: 10.1016/j.celrep.2022.110928. PubMed |
Hijacking of transcriptional condensates by endogenous retroviruses.
Asimi V, Sampath Kumar A, Niskanen H, Riemenschneider C, Hetzel S, Naderi J, Fasching N, Popitsch N, Du M, Kretzmer H, Smith ZD, Weigert R, Walther M, Mamde S, Meierhofer D, Wittler L, Buschow R, Timmermann B, Cisse II, Ameres SL, Meissner A, Hnisz D.
Nat Genet. 2022 Aug;54(8):1238-1247. doi: 10.1038/s41588-022-01132-w. Epub 2022 Jul 21.
PubMed
Associated Plasmids |
| KDM3A and KDM3B Maintain Naive Pluripotency Through the Regulation of Alternative Splicing. Dillingham CM, Cormaty H, Morgan EC, Tak AI, Esgdaille DE, Boutz PL, Sridharan R. bioRxiv [Preprint]. 2024 Jan 23:2023.05.31.543088. doi: 10.1101/2023.05.31.543088. PubMed |
| The intrinsically disordered region of eIF5B stimulates IRES usage and nucleates biological granule formation. Harris MT, Marr MT 2nd. Cell Rep. 2023 Oct 31;42(10):113283. doi: 10.1016/j.celrep.2023.113283. Epub 2023 Oct 19. PubMed |
| Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9. Eaton JD, Board J, Davidson L, Estell C, West S. Elife. 2024 Jul 8;13:RP92764. doi: 10.7554/eLife.92764. PubMed |
| Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity. Zhang S, Roeder RG. Nat Struct Mol Biol. 2025 Jan;32(1):98-112. doi: 10.1038/s41594-024-01384-6. Epub 2024 Sep 9. PubMed |
| Composition and RNA binding specificity of metazoan RNase MRP. Liu Y, He S, Pyo A, Zheng S, Chen M, Cheloufi S, Slavov N, Marzluff WF, Murn J. bioRxiv [Preprint]. 2025 Feb 23:2025.02.21.639568. doi: 10.1101/2025.02.21.639568. PubMed |
| A nuclear RNA degradation code is recognized by PAXT for eukaryotic transcriptome surveillance. Soles LV, Liu L, Zou X, Yoon Y, Li S, Tian L, Valdez M, Yu AM, Yin H, Li W, Ding F, Seelig G, Li L, Shi Y. Mol Cell. 2025 Apr 17;85(8):1575-1588.e9. doi: 10.1016/j.molcel.2025.03.010. Epub 2025 Apr 4. PubMed |
| KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells. Dillingham CM, Cormaty H, Morgan EC, Tak AI, Esgdaille DE, Boutz PL, Sridharan R. iScience. 2025 May 8;28(6):112612. doi: 10.1016/j.isci.2025.112612. eCollection 2025 Jun 20. PubMed |
| Reversible proliferative arrest induced by rapid depletion of RNase MRP. Liu Y, He S, Pyo K, Franklin R, Maaz IB, Cai C, Shah K, Cheloufi S, Marzluff WF, Murn J. Nat Commun. 2025 Jun 18;16(1):5342. doi: 10.1038/s41467-025-60471-4. PubMed |
| The PRMT5-splicing axis is a critical oncogenic vulnerability that regulates detained intron splicing. Fowler CE, O'Hearn NA, Salus GJ, Singh A, Boutz PL, Lees JA. iScience. 2025 Jun 20;28(7):112965. doi: 10.1016/j.isci.2025.112965. eCollection 2025 Jul 18. PubMed |
| Composition and RNA binding specificity of metazoan RNase MRP. Liu Y, He S, Pyo K, Zheng S, Chen M, Braschi B, Cheloufi S, Slavov N, Marzluff WF, Murn J. Nucleic Acids Res. 2025 Aug 27;53(16):gkaf829. doi: 10.1093/nar/gkaf829. PubMed |
| Proteomic Analysis of Human Topoisomerases Reveals Their Distinct and Diverse Cellular Functions. Zhang H, Xiong Y, Chen Z, Chen J. Mol Cell Proteomics. 2025 Nov;24(11):101082. doi: 10.1016/j.mcpro.2025.101082. Epub 2025 Oct 1. PubMed |
| Sequential verification of transcription by Integrator and Restrictor. Estell C, Lazowski K, Eaton JD, West S. Mol Cell. 2025 Nov 6;85(21):3982-3998.e6. doi: 10.1016/j.molcel.2025.09.025. Epub 2025 Oct 17. PubMed |
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