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AI-generated MLH1 small binder improves prime editing efficiency.

Park JC, Uhm H, Kim YW, Oh YE, Lee JH, Yang J, Kim K, Bae S
Cell. 2025 Aug 1:S0092-8674(25)00799-8. doi: 10.1016/j.cell.2025.07.010. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
228868pCMV-PE7-SB2PE7 connected to MLH1-SB and MLH1-SB-NLS via 2A sequence
228869pCMV-PE7-SBPE7 connected to MLH1-SB via 2A sequence
228870pCMV-PE7-SB-NLSPE7 connected to MLH1-SB-NLS via 2A sequence
228871pCMV-PuroR-2A-MLH1-SBPlasmid for MLH1-SB overexpression

Antibodies from Article