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High-performance genetically targetable optical neural silencing by light-driven proton pumps.
Chow BY, Han X, Dobry AS, Qian X, Chuong AS, Li M, Henninger MA, Belfort GM, Lin Y, Monahan PE, Boyden ES
Nature. 2010 Jan 7. 463(7277):98-102.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
22217FCK-Arch-GFPLentiviral expression of Arch-GFP for optogenetic inhibition
22221FCK-Arch-CFPLentiviral expression of Arch-CFP for optogenetic inhibition
22222AAV-FLEX-Arch-GFPCre-dependent viral expression of Arch-GFP for neuronal inhibition
22223FCK-Mac-GFPLentiviral expression of Mac-GFP for optogenetic inhibition
22224FCK-ss-Prl-Arch-GFPLentiviral expression of Arch-GFP, with N-terminal MHC Class I antigen signal sequence (ss) and Prolactin signal sequence (Prl), for optogenetic inhibition.
37810pAAV-CAG-Arch-GFP
58803pAAV-CAG-FLEX-Mac-GFPAAV-mediated expression of Mac-GFP under the CAG promoter, in floxed/reversed (Cre-dependent) manner
58849pAAV-CaMKII-Mac-GFPAAV expression of Mac-GFP under the CaMKII promoter
58852pAAV-Syn-FLEX-Mac-GFPAAV-mediated expression of Mac-GFP under the Syn promoter, in floxed/reversed (Cre-dependent) manner
58853pAAV-Syn-Mac-GFPAAV-mediated expression of Mac-GFP under the Syn promoter

Antibodies from Article