Focused Ras Synthetic Lethal Human CRISPR Knockout Library
(Pooled Library #92352)
The Sabatini/Lander CRISPR pooled library is a focused gRNA library that targets synthetic lethal candidate and control genes with oncogenic Ras.
These pooled libraries were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the pooled libraries were described, and include Addgene in the Materials and Methods of your future publications.
Example for your Materials & Methods section:Focused Ras Synthetic Lethal Human CRISPR Knockout Library was a gift from David Sabatini and Eric Lander (Addgene # 92352)
For your References section:Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras. Wang T, Yu H, Hughes NW, Liu B, Kendirli A, Klein K, Chen WW, Lander ES, Sabatini DM. Cell. 2017 Feb 1. pii: S0092-8674(17)30061-2. doi: 10.1016/j.cell.2017.01.013. PubMed 28162770