We narrowed to 907 results for: inha

1. pLenti-H3.3(K36M)-3AID-HA-2A-mTurquoiseBSD

   Plasmid

   #225703

   Purpose

   Lentiviral expression of AID degron tagged H3.3(K36M) and mTurquoise fused BlasticidinR

   Depositor

   Lacra Bintu

   Article

   Sinha et al bioRxiv [Preprint]. 2023 Oct 14:2023.10.

   Insert

   H3.3 (K36M) (H3-3A, H3-3B Human)
   

   Use

   Lentiviral and Synthetic Biology

   Tags

   3xAID HA and T2A-mTurquoise

   Expression

   Mammalian

   Mutation

   K36M

   Promoter

   pEF1A

   Available since

   Oct. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLenti-H3.3(WT)-3AID-HA-2A-mCherryBSD

   Plasmid

   #225697

   Purpose

   Lentiviral expression of AID degron tagged Wildtype H3.3 and mCherry fused BlasticidinR

   Depositor

   Lacra Bintu

   Article

   Sinha et al bioRxiv [Preprint]. 2023 Oct 14:2023.10.

   Insert

   H3.3 (WT) (H3-3A, H3-3B Human)
   

   Use

   Lentiviral and Synthetic Biology

   Tags

   3xAID HA and T2A-mCherry

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pLenti-H3.3(K27M)-3AID-HA-2A-mCherryBSD

   Plasmid

   #225698

   Purpose

   Lentiviral expression of AID degron tagged H3.3(K27M) and mCherry fused BlasticidinR

   Depositor

   Lacra Bintu

   Article

   Sinha et al bioRxiv [Preprint]. 2023 Oct 14:2023.10.

   Insert

   H3.3 (K27M) (H3-3A, H3-3B Human)
   

   Use

   Lentiviral and Synthetic Biology

   Tags

   3xAID HA and T2A-mCherry

   Expression

   Mammalian

   Mutation

   K27M

   Promoter

   pEF1A

   Available since

   Oct. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. lentiCRISPR v2-Nr4a1 double gRNAs

   Plasmid

   #162791

   Purpose

   Multiplex Guide RNAs to generate Nr4a1 knockout by CRISPR

   Depositor

   Matthew Steinhauser

   Article

   Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

   Insert

   Multiplex Nr4a1 gRNA 1 and 2 (Nr4a1 Mouse)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   hU6

   Available since

   Dec. 11, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. MSCV-HA-Nr4a1-AA

   Plasmid

   #160942

   Purpose

   Generation of retrovirus for the overexpression of Nr4a1 mutant (287C 288EAA)

   Depositor

   Matthew Steinhauser

   Article

   Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

   Insert

   Nr4a1 (Nr4a1 Mouse)
   

   Use

   Retroviral

   Tags

   HA tag

   Expression

   Mammalian

   Mutation

   Change Cys 287 Glu 288 into Ala Ala

   Promoter

   MSCV-LTR

   Available since

   Dec. 11, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. MSCV-HA-Nr4a1-Zf2

   Plasmid

   #160944

   Purpose

   Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 2 deletion)

   Depositor

   Matthew Steinhauser

   Article

   Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

   Insert

   Nr4a1 (Nr4a1 Mouse)
   

   Use

   Retroviral

   Tags

   HA tag

   Expression

   Mammalian

   Mutation

   Deletion of Zinc finger 2 (C306 to C330)

   Promoter

   MSCV-LTR

   Available since

   Dec. 11, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. MSCV-HA-Nr4a1-Zf1

   Plasmid

   #160943

   Purpose

   Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 1 deletion)

   Depositor

   Matthew Steinhauser

   Article

   Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

   Insert

   Nr4a1 (Nr4a1 Mouse)
   

   Use

   Retroviral

   Tags

   HA tag

   Expression

   Mammalian

   Mutation

   Deletion of Zinc finger 1 (C270 to C290)

   Promoter

   MSCV-LTR

   Available since

   Dec. 10, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV-syn-AICD-IRES-hrGFP

   Plasmid

   #107548

   Purpose

   high transduction efficiency AAV-mediated synapsin promoter-dependent expression of AICD (last 50 amino acids of APP) and IRES-mediated co-expression of hrGFP

   Depositor

   Hélène Marie

   Article

   Pousinha et al Elife. 2017 Jul 6;6. doi: 10.7554/eLife.

   Insert

   AICD (APP Human)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   None

   Promoter

   human synapsin

   Available since

   May 1, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-AICD-NLS-IRES-hrGFP

   Plasmid

   #107543

   Purpose

   AAV-mediated expression of AICD (last 50 amino acids of APP) with Nuclear Localisation Signal (NLS: CCAAAAAAGAAGAGAAAGGTA) at C-term end and IRES-mediated co-expression of hrGFP

   Depositor

   Hélène Marie

   Article

   Pousinha et al Elife. 2017 Jul 6;6. doi: 10.7554/eLife.

   Insert

   AICD-NLS (APP Human)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   None

   Promoter

   CMV

   Available since

   May 1, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-AICD-NES-IRES-hrGFP

    Plasmid

    #107544

    Purpose

    AAV-mediated expression of AICD (last 50 amino acids of APP) with Nuclear Export Signal (NES: CTCCCTCCACTAGAGCGACTAACCTTA) at C-term end and IRES-mediated co-expression of hrGFP

    Depositor

    Hélène Marie

    Article

    Pousinha et al Elife. 2017 Jul 6;6. doi: 10.7554/eLife.

    Insert

    AICD-NES (APP Human)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    None

    Promoter

    CMV

    Available since

    May 2, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pLenti-K36M TAIL[1-44]-3AID-HA-2A-mCherryBSD

    Plasmid

    #225872

    Purpose

    Lentiviral expression of AID degron tagged H3.3(K36M) histone tail corresponding to amino acids 1-44 and mCherry fused BlasticidinR

    Depositor

    Lacra Bintu

    Article

    Sinha et al bioRxiv [Preprint]. 2023 Oct 14:2023.10.

    Insert

    H3.3(K36M) amino acids 1-44 (H3-3A, H3-3B Human, Synthetic)
    

    Use

    Lentiviral and Synthetic Biology

    Tags

    3xAID HA and T2A-mCherry

    Expression

    Mammalian

    Mutation

    amino acids 1-44 from H3.3 K36M

    Promoter

    Available since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV.EF1a.ChR2-YFP.WPRE.hGH

    Plasmid

    #100056

    Purpose

    AAV expression of ChR2 fused to YFP driven byEF1a promoter for optogenetic activation

    Depositor

    Karl Deisseroth

    Insert

    ChR2
    

    Use

    AAV

    Tags

    EYFP

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    Jan. 31, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA4_ChR2opt_mKATE

    Plasmid

    #67958

    Purpose

    optical depolarization of mammalian cells

    Depositor

    Andreas Offenhäusser

    Insert

    Channelrhodopsin 2 opt
    

    Use

    Tags

    mKatushka

    Expression

    Mammalian

    Mutation

    synthetically produced for mammalian optimized co…

    Promoter

    CMV -TetON

    Available since

    Sept. 4, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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14. hSyn1-FLEX-hChR2-tdtomato

    Plasmid

    #41015

    Depositor

    Karel Svoboda

    Insert

    Channelrhodopsin-2
    

    Use

    Adenoviral

    Tags

    tdtomato

    Expression

    Mammalian

    Mutation

    codon-optimized (human)

    Promoter

    synapsin

    Available since

    Nov. 6, 2012

    Availability

    Academic Institutions and Nonprofits only

15. pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40

    Plasmid

    #100054

    Purpose

    AAV expression of humanized ChR2 with H134R mutation fused to mCherry driven by CAG promoter for optogenetic activation

    Depositor

    Karl Deisseroth

    Has Service

    AAV1, AAV2, AAV5, and AAV9

    Insert

    channelrhodopsin-2
    

    Use

    AAV

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    H134R mutation in ChR2

    Promoter

    CAG

    Available since

    Jan. 31, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAAV-double floxed-eNpHR-EYFP-WPRE-pA

    Plasmid

    #20949

    Purpose

    Cre-activated AAV expression of halorhodopsin 2.0 (eNpHR) fused to EYFP for optogenetic inhibition

    Depositor

    Karl Deisseroth

    Has Service

    AAV9

    Insert

    halorhodopsin
    

    Use

    AAV

    Tags

    EYFP

    Expression

    Mammalian

    Mutation

    Promoter

    EF1alpha

    Available since

    May 13, 2009

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. hSyn-Aion-ts-mScarlet-ER

    Plasmid

    #192577

    Purpose

    AAV-vector for optogenetic long-term silencing of neurons

    Depositor

    Simon Wiegert

    Insert

    Aion
    

    Use

    AAV

    Tags

    ts-mScarlet-ER

    Expression

    Mammalian

    Mutation

    T59S, E83N, E90Q, E101S, V117R, E123S, C128A,D156…

    Promoter

    human synapsin

    Available since

    Dec. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. CaMKII-Aion-ts-citrine-ER

    Plasmid

    #192576

    Purpose

    AAV-vector for optogenetic long-term silencing of excitatory neurons

    Depositor

    Simon Wiegert

    Insert

    Aion
    

    Use

    AAV

    Tags

    ts-Citrine-ER

    Expression

    Mammalian

    Mutation

    T59S, E83N, E90Q, E101S, V117R, E123S, C128A,D156…

    Promoter

    CaMKIIa(0.4)

    Available since

    Dec. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. mDlx-Aion-citrine

    Plasmid

    #192572

    Purpose

    AAV-vector for optogenetic long-term silencing of GABAergic neurons

    Depositor

    Simon Wiegert

    Insert

    Aion
    

    Use

    AAV

    Tags

    Citrine

    Expression

    Mammalian

    Mutation

    T59S, E83N, E90Q, E101S, V117R, E123S, C128A,D156…

    Promoter

    minimal Dlx

    Available since

    Dec. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. hSyn-Aion-mKate2

    Plasmid

    #192574

    Purpose

    AAV-vector for optogenetic long-term silencing of neurons

    Depositor

    Simon Wiegert

    Insert

    Aion
    

    Use

    AAV

    Tags

    mKate2

    Expression

    Mammalian

    Mutation

    T59S, E83N, E90Q, E101S, V117R, E123S, C128A,D156…

    Promoter

    human synapsin

    Available since

    Dec. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge