We narrowed to 15,189 results for: invs

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pENTR221-ITGB1(no stop)

Plasmid

#215453

Purpose

Gateway entry vector with integrin beta1 wild-type (WT) without a stop codon

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

ITGB1 (ITGB1 Human)

Use

Gateway entry vector

Mutation

Silent mutations added to disrupt shRNA binding a…

Promoter

none

Available Since

Sept. 4, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pEF.DEST51-PTPN11(D425A,C459S)-Clover

Plasmid

#215526

Purpose

Expression vector with a clover-tagged phosphatase-inactive Shp2 mutant (D425A,C459S)

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

PTPN11 (PTPN11 Human)

Tags

Clover

Expression

Mammalian

Mutation

D425A, C459S (Phosphatase inactive)

Promoter

EF1a

Available Since

Sept. 3, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pENTR2b-PTPN11(D425A,C459S)-Clover

Plasmid

#215520

Purpose

Gateway entry vector with a clover-tagged phosphatase-inactive Shp2 mutant (D425A,C459S)

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

PTPN11 (PTPN11 Human)

Use

Gateway entry vector

Tags

Clover

Mutation

D425A, C459S (Phosphatase inactive)

Promoter

none

Available Since

Sept. 3, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pENTR2b-ITGB1(YYFF)

Plasmid

#215451

Purpose

Gateway entry vector with integrin beta1 NPxY mutant (YYFF)

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

ITGB1 (ITGB1 Human)

Use

Gateway entry vector

Mutation

Mutations in the NPxY sites Y783F, Y795F; Silent …

Promoter

none

Available Since

May 29, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pENTR2b-ITGB1(WT)-mRuby2

Plasmid

#215446

Purpose

Gateway entry vector with integrin beta1 tagged with mRuby2

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

ITGB1 (ITGB1 Human)

Use

Gateway entry vector

Tags

mRuby2

Mutation

Silent mutations added to disrupt shRNA binding a…

Promoter

none

Available Since

May 29, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pLentiCRISPR V2 Neo PTEN sgRNA5

Plasmid

#233246

Purpose

Knock out of murine PTEN

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

PTEN (Pten Mouse)

Use

Lentiviral

Available Since

March 20, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo sgITGA5_5

Plasmid

#233253

Purpose

Knock out of murine ITGA5

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

ITGA5 (Itga5 Mouse)

Use

Lentiviral

Available Since

March 19, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo sgITGA5_4

Plasmid

#233252

Purpose

Knock out of murine ITGA5

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

ITGA5 (Itga5 Mouse)

Use

Lentiviral

Available Since

March 19, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo sgITGA5_1

Plasmid

#233251

Purpose

Knock out of murine ITGA5

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

ITGA5 (Itga5 Mouse)

Use

Lentiviral

Available Since

March 19, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo sgAGAP1_3

Plasmid

#233248

Purpose

Knock out of murine AGAP1

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

AGAP1 (Agap1 Mouse)

Use

Lentiviral

Available Since

March 11, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo PTEN sgRNA2

Plasmid

#233245

Purpose

Knock out of murine PTEN

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

PTEN (Pten Mouse)

Use

Lentiviral

Available Since

March 11, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 Neo sgAGAP1_2

Plasmid

#233247

Purpose

Knock out of murine AGAP1

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

AGAP1 (Agap1 Mouse)

Use

Lentiviral

Available Since

March 11, 2025

Availability

Academic Institutions and Nonprofits only

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pUC-hU6-shBACH1_BFP

Plasmid

#199217

Purpose

Expression plasmid with shRNAmiR targeting BACH1, with a BFP reporter on the backbone.

Depositor

Gabor Balazsi

Article

Wan et al Nat Chem Biol. 2023 Jul;19(7):887-899. d

Insert

shBACH1 (BACH1 Synthetic)

Use

RNAi

Promoter

human U6

Available Since

Aug. 2, 2023

Availability

Academic Institutions and Nonprofits only

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pUC_hU6-shRKIP_BFP

Plasmid

#199216

Purpose

Expression plasmid with shRNAmiR targeting RKIP (PEBP1), with a BFP reporter on the backbone.

Depositor

Gabor Balazsi

Article

Wan et al Nat Chem Biol. 2023 Jul;19(7):887-899. d

Insert

shBACH1 (BACH1 Synthetic)

Use

RNAi

Promoter

human U6

Available Since

June 28, 2023

Availability

Academic Institutions and Nonprofits only

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pCS2plus-TDP-43

Plasmid

#162608

Purpose

Allows for transcription of TDP-43 mRNA for injection into zebrafish embryos for BiFC assays

Depositor

Marco Morsch

Article

Don et al Mol Neurobiol. 2021 May;58(5):2061-2074.

Insert

TARDBP (TARDBP Human)

Expression

Mammalian

Available Since

June 10, 2021

Availability

Academic Institutions and Nonprofits only

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MSCV-HA-Nr4a1-Zf2

Plasmid

#160944

Purpose

Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 2 deletion)

Depositor

Matthew Steinhauser

Article

Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

Insert

Nr4a1 (Nr4a1 Mouse)

Use

Retroviral

Tags

HA tag

Expression

Mammalian

Mutation

Deletion of Zinc finger 2 (C306 to C330)

Promoter

MSCV-LTR

Available Since

Dec. 11, 2020

Availability

Academic Institutions and Nonprofits only

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MSCV-HA-Nr4a1-Zf1

Plasmid

#160943

Purpose

Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 1 deletion)

Depositor

Matthew Steinhauser

Article

Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

Insert

Nr4a1 (Nr4a1 Mouse)

Use

Retroviral

Tags

HA tag

Expression

Mammalian

Mutation

Deletion of Zinc finger 1 (C270 to C290)

Promoter

MSCV-LTR

Available Since

Dec. 10, 2020

Availability

Academic Institutions and Nonprofits only

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pLEX303-GFP-IQSEC1 v2N/v4C-WT

Plasmid

#162022

Purpose

Expression of IQSEC1 chimera

Depositor

David Bryant

Article

Nacke et al Nat Commun. 2021 Mar 12;12(1):1623. doi:

Insert

IQSEC1 (IQSEC1 Human)

Use

Lentiviral

Mutation

v2N/v4C

Available Since

Dec. 7, 2020

Availability

Academic Institutions and Nonprofits only

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pLEX303-GFP-IQSEC1 v4N/v1C-WT

Plasmid

#162024

Purpose

Expression of IQSEC1 chimera

Depositor

David Bryant

Article

Nacke et al Nat Commun. 2021 Mar 12;12(1):1623. doi:

Insert

IQSEC1 (IQSEC1 Human)

Use

Lentiviral

Mutation

v4N/v1C

Available Since

Dec. 7, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
pLEX303-GFP-IQSEC1 v2N/v1C-WT

Plasmid

#162023

Purpose

Expression of IQSEC1 chimera

Depositor

David Bryant

Article

Nacke et al Nat Commun. 2021 Mar 12;12(1):1623. doi:

Insert

IQSEC1 (IQSEC1 Human)

Use

Lentiviral

Mutation

v2N/v1C

Available Since

Dec. 7, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge