We narrowed to 373 results for: tp53

1. pT5T_hp53_ST_CR2

   Plasmid

   #34923

   Depositor

   Thanos Halazonetis

   Article

   Petty et al EMBO J. 2011 Jun 1;30(11):2167-76. Epub

   Insert

   p53 DNA-binding (Res 94-358, deletion 293-321) (TP53 Human)
   

   Expression

   Bacterial

   Mutation

   C135V, C141V, W146Y, C182S, V203A, R209P, C229Y, …

   Promoter

   T7

   Available Since

   Feb. 22, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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2. pEN_TTmiRC2_p53DD

   Plasmid

   #136520

   Purpose

   Used as a donor vector containing N-term 3xFLAG to clone into pSLIK

   Depositor

   Kevin Janes

   Article

   Pereira et al Sci Signal. 2020 Apr 14;13(627). pii: 13

   Insert

   p53DD (Trp53 Mouse)
   

   Use

   Entry vector for gateway cloning

   Tags

   3x FLAG

   Mutation

   This construct was created by PCR from the pBabe …

   Available Since

   Oct. 3, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pRRLNeo-pEF1a-p53ashL344P-mKate2-splitmVenusN

   Plasmid

   #69586

   Purpose

   Expresses mutated p53-L344P tagged with mKate2 and split N-term mVenus

   Depositor

   Galit Lahav

   Article

   Gaglia et al Mol Syst Biol. 2014 Oct 24;10:753. doi:

   Insert

   p53-L344P (TP53 Human)
   

   Use

   Lentiviral

   Tags

   mKate2 and split mVenus - N term

   Expression

   Mammalian

   Mutation

   p53 L344P mutation that prevents dimerization and…

   Promoter

   EF1alpha

   Available Since

   April 14, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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4. pPBneo-CIBN-lin-p53CT(98-393)-6KQ-mNeonGreen-NLSx3

   Plasmid

   #241848

   Purpose

   Expresses an improved localizer of Opto-p53 in mammalian cells.

   Depositor

   Kazuhiro Aoki

   Article

   Tsuruoka et al Cell Struct Funct. 2025 Jun 12. doi: 10.

   Insert

   p53 (TP53 Human)
   

   Tags

   CIBN and mNeonGreen

   Expression

   Mammalian

   Mutation

   p53 C-terminus (97-393 aa) containing six acetyla…

   Promoter

   CAGGS promoter

   Available Since

   Sept. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pPBbsr2-NLSx3-miRFP703-dSal-p53NT(1-97)-L22Q/W23S/W53Q/F54S-lin-hCRY2

   Plasmid

   #241847

   Purpose

   Expresses a negative control of the actuator of Opto-p53 in mammalian cells.

   Depositor

   Kazuhiro Aoki

   Article

   Tsuruoka et al Cell Struct Funct. 2025 Jun 12. doi: 10.

   Insert

   p53 (TP53 Human)
   

   Tags

   CRY2 and miRFP703

   Expression

   Mammalian

   Mutation

   N-terminus (1-97 aa) containing L22Q/W23S/W53Q/F5…

   Promoter

   CAGGS promoter

   Available Since

   Sept. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pPBbsr2-NLSx3-miRFP703-dSal-p53NT(1-97)-5SD-lin-hCRY2

   Plasmid

   #241846

   Purpose

   Expresses an improved actuator of Opto-p53 in mammalian cells.

   Depositor

   Kazuhiro Aoki

   Article

   Tsuruoka et al Cell Struct Funct. 2025 Jun 12. doi: 10.

   Insert

   p53 (TP53 Human)
   

   Tags

   CRY2 and miRFP703

   Expression

   Mammalian

   Mutation

   N-terminus (1-97 aa) containing five phosphorylat…

   Promoter

   CAGGS promoter

   Available Since

   Sept. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pET28-p53 (1-73) (K24N)

   Plasmid

   #62079

   Purpose

   Expression of human p53 (1-73) (K24N) in e. coli

   Depositor

   Gary Daughdrill

   Article

   Zhan et al Proteins. 2013 Oct;81(10):1738-47. doi:

   Insert

   p53 (TP53 Human)
   

   Tags

   His

   Expression

   Bacterial

   Mutation

   contains TAD residues 1-73; K24N

   Promoter

   T7

   Available Since

   Jan. 29, 2015

   Availability

   Academic Institutions and Nonprofits only

8. pRRLNeo-pEF1a-p53ashL344A-mKate2-splitmVenusN

   Plasmid

   #69584

   Purpose

   Expresses mutated p53-L344A tagged with mKate2 and split N-term mVenus

   Depositor

   Galit Lahav

   Article

   Gaglia et al Mol Syst Biol. 2014 Oct 24;10:753. doi:

   Insert

   p53-L344A (TP53 Human)
   

   Use

   Lentiviral

   Tags

   mKate2 and split mVenus - N term

   Expression

   Mammalian

   Mutation

   p53 L344A mutation that prevents tetramerization …

   Promoter

   EF1alpha

   Availability

   Academic Institutions and Nonprofits only

   

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9. pRRLHygro-pEF1a-p53ashL344A-mKate2-splitmVenusC

   Plasmid

   #69585

   Purpose

   Expresses mutated p53-L344A tagged with mKate2 and split C-term mVenus

   Depositor

   Galit Lahav

   Article

   Gaglia et al Mol Syst Biol. 2014 Oct 24;10:753. doi:

   Insert

   p53-L344A (TP53 Human)
   

   Use

   Lentiviral

   Tags

   mKate2 and split mVenus - C term

   Expression

   Mammalian

   Mutation

   p53 L344A mutation that prevents tetramerization …

   Promoter

   EF1alpha

   Availability

   Academic Institutions and Nonprofits only

   

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10. shp63alpha pLKO.1 puro

    Plasmid

    #19120

    Depositor

    Bob Weinberg

    Article

    Godar et al Cell. 2008 Jul 11. 134(1):62-73.

    Insert

    small hairpin RNA against tumor protein p63 (TP63 Human)
    

    Use

    Lentiviral and RNAi

    Expression

    Mammalian

    Available Since

    Sept. 9, 2008

    Availability

    Academic Institutions and Nonprofits only

    

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11. Px461-Cas9n-Trp53-sgRNA-beta

    Plasmid

    #88847

    Purpose

    CRISPR KO of Trp53

    Depositor

    Joan Massague

    Article

    Wang et al Cell Stem Cell. 2017 Jan 5;20(1):70-86.

    Insert

    Trp53 (Trp53 Mouse)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    July 11, 2017

    Availability

    Academic Institutions and Nonprofits only

12. Px461-Cas9n-Trp53-sgRNA-alpha

    Plasmid

    #88846

    Purpose

    CRISPR KO of Trp53

    Depositor

    Joan Massague

    Article

    Wang et al Cell Stem Cell. 2017 Jan 5;20(1):70-86.

    Insert

    Trp53 (Trp53 Mouse)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    July 11, 2017

    Availability

    Academic Institutions and Nonprofits only

13. pX330 p53

    Plasmid

    #59910

    Purpose

    pX330 backbone expressing sgRNA targeting p53 to edit mouse p53. Expresses Cas9 from CBh promoter

    Depositor

    Tyler Jacks

    Article

    Xue et al Nature. 2014 Aug 6. doi: 10.1038/nature1

    Insert

    sgRNA targeting p53 (Trp53 Mouse)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    March 16, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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14. shp53 pLKO.1 puro

    Plasmid

    #19119

    Purpose

    3rd gen lentiviral vector for knocking down p53 gene expression

    Depositor

    Bob Weinberg

    Article

    Godar et al Cell. 2008 Jul 11. 134(1):62-73.

    Insert

    small hairpin RNA against tumor protein p53 (TP53 Human)
    

    Use

    Lentiviral and RNAi

    Expression

    Mammalian

    Available Since

    Sept. 9, 2008

    Availability

    Academic Institutions and Nonprofits only

    

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15. sg_Trp53_i3-ipUSEPR-TR657

    Plasmid

    #228929

    Purpose

    Knockdown of Trp53 in mammalian cells

    Depositor

    Sika Zheng

    Article

    Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

    Insert

    sg_Trp53_i3 (Trp53 Mouse)
    

    Use

    Lentiviral

    Available Since

    Jan. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pGLS3-5xHRE-p53(K164R)

    Plasmid

    #72555

    Purpose

    Hypoxia induced mutant p53. Contains the HRE from VEGF sequence (5 repeats) upstream of p53 K164R.

    Depositor

    Ester Hammond

    Article

    Leszczynska et al J Clin Invest. 2015 Jun;125(6):2385-98.

    Insert

    p53 (TP53 Human)
    

    Tags

    5XHRE

    Expression

    Mammalian

    Mutation

    K164R

    Promoter

    E1B minimal promoter

    Available Since

    March 9, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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17. pGEX6P2-p53 (1-90) (72R)

    Plasmid

    #62081

    Purpose

    Expression of human p53 (TAD residues 1-90) (72R) in e. coli

    Depositor

    Gary Daughdrill

    Article

    Borcherds et al Nat Chem Biol. 2014 Dec;10(12):1000-2. d

    Insert

    p53 (TP53 Human)
    

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Contains TAD/PP residues 1-90, 72R

    Promoter

    tac

    Available Since

    Feb. 2, 2015

    Availability

    Academic Institutions and Nonprofits only

18. pSico p53

    Plasmid

    #12089

    Purpose

    Cre-regulated lentiviral shRNA vector. Cre addition causes EGFP to be recombined out of the construct, activating p53 shRNA expression.

    Depositor

    Tyler Jacks

    Article

    Ventura et al Proc Natl Acad Sci U S A. 2004 Jul 13. 1

    Insert

    p53 shRNA (Trp53 Mouse)
    

    Use

    Cre/Lox, Lentiviral, and RNAi

    Expression

    Mammalian

    Mutation

    EGFP is expressed from this plasmid as a marker, …

    Available Since

    Aug. 4, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. sg_Trp53_i4-ipUSEPR-TR657

    Plasmid

    #228930

    Purpose

    Knockdown of Trp53 in mammalian cells

    Depositor

    Sika Zheng

    Article

    Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

    Insert

    sg_Trp53_i4 (Trp53 sequence: GTCGCTACCTACAGCCAGGA, Mouse)
    

    Use

    Lentiviral

    Available Since

    Jan. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pSicoR p53

    Plasmid

    #12090

    Purpose

    Cre-regulated lentiviral shRNA vector. Cre addition causes both EGFP and shRNA to be recombined out of the construct, turning OFF p53 shRNA expression.

    Depositor

    Tyler Jacks

    Article

    Ventura et al Proc Natl Acad Sci U S A. 2004 Jul 13. 1

    Insert

    p53 shRNA (Trp53 Mouse)
    

    Use

    Cre/Lox, Lentiviral, and RNAi

    Expression

    Mammalian

    Mutation

    EGFP is expressed from this plasmid as a marker, …

    Available Since

    Aug. 4, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge