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pRS314 snu114(G145A)

Plasmid

#111319

Purpose

snu114(G145A)

Depositor

Christine Guthrie

Article

Brenner et al Genetics. 2005 Jul;170(3):1063-80. doi:

Insert

SNU114

Expression

Yeast

Mutation

snu114 G145A

Available Since

July 10, 2018

Availability

Academic Institutions and Nonprofits only

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pDONR221 Tma16

Plasmid

#63779

Purpose

yeast ORF Tma16 in the Gateway entry vector pDONR221

Depositor

Susan Baserga

Article

McCann et al Genes Dev. 2015 Apr 15;29(8):862-75. doi

Insert

Tma16 (TMA16 Budding Yeast)

Use

Gateway donor vector

Available Since

July 29, 2016

Availability

Academic Institutions and Nonprofits only

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pMES140

Plasmid

#71849

Purpose

Complementation of NME1 gene disruption or mutation in yeast

Depositor

David Clayton, Mark Schmitt

Article

Schmitt et al Mol Cell Biol. 1993 Dec;13(12):7935-41.

Insert

NME1 (NME1 Budding Yeast)

Expression

Yeast

Promoter

NME1

Available Since

Jan. 5, 2016

Availability

Academic Institutions and Nonprofits only

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LRRK2_1867_2161_V1922T_C2024S_C2025S_F2079Y_L2115A

Plasmid

#40412

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867-2161; V1922T, C2024S, C2025S, F2079Y, L211…

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_F1908A_L1936R_V2048S_F2079G

Plasmid

#40413

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867-2161; F1908A, L1936R, V2048S, F2079G

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_F1908A_L1936R_V2048S_I2131Q

Plasmid

#40418

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867-2161; F1908A, L1936R, V2048S, I2131Q

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_F1908A_L1936R_F2079G_I2131Q

Plasmid

#40422

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; F1908A, L1936R, F2079G, I2131Q

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_F1908A_L1936R_V2048S_F2079G_I2131Q

Plasmid

#40423

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; F1908A, L1936R, V2048S, F2079G, I213…

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_L1914N_V2048T_F2083Y_I2131S

Plasmid

#40425

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; L1914N, V2048T, F2083Y, I2131S

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_L1914N_L1936Y_V2048T_F2083Y_I2131S

Plasmid

#40426

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

1867_2161; L1914N, L1936Y, V2048T, F2083Y, I2131S

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
pEMB017 NP_9409803_LRRK2_1867_2161_L1914N_V2048T_F2083Y

Plasmid

#40427

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; L1914N, V2048T, F2083Y

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_L1914A_L1976Y_C2024S_C2025S_I2049Q_F2083A

Plasmid

#40428

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; L1914A, L1976Y, C2024S, C2025S, I204…

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_L1914A_C2024S_C2025S_I2049Q

Plasmid

#40430

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; L1914A, C2024S, C2025S, I2049Q

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_L1916A_L1936R_L2005N_V2074Y_L2092Y

Plasmid

#40432

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867-2161; L1916A, L1936R, L2005N, V2074Y, L209…

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_L1914A_L1976Y_I2049Q_F2083A

Plasmid

#40433

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; L1914A, L1976Y, I2049Q, F2083A

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_L1916N_L1936R_L1976A_I2049A_L2092N

Plasmid

#40438

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; L1916N, L1936R, L1976A, I2049A, L209…

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_L1916N_L1976A_I2049A_V2074A_L2092N

Plasmid

#40439

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; L1916N, L1976A, I2049A, V2074A, L209…

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_V1922D_L2005R_V2074A_L2115W

Plasmid

#40441

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; V1922D, L2005R, V2074A, L2115W

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_F1908A_V2048S_F2079G_I2131Q

Plasmid

#40447

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; F1908A, V2048S, F2079G, I2131Q

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
LRRK2_1867_2161_L1914A_L1976Y_C2024S_C2025S_I2049Q

Plasmid

#40452

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

GST-Tev and HisTev

Mutation

aa1867_2161; L1914A, L1976Y, C2024S, C2025S, I204…

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
pBACgus/LRRK2 1867-2141 C-His

Plasmid

#40376

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

6xHis

Mutation

WT aa1867-2141

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
pBACgus/LRRK2 1867-2176 C-His

Plasmid

#40378

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

6xHis

Mutation

WT aa1867-2176

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
pBACgus/LRRK2 C-His_T2031E

Plasmid

#40379

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

6xHis

Mutation

aa1867-2186, T2031E

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
pBACgus/LRRK2 C-His_C2024S/C2025S

Plasmid

#40383

Depositor

Michael J Fox Foundation MJFF

Insert

LRRK2 (LRRK2 Human)

Use

Baculovirus

Tags

6xHis

Mutation

aa1867-2186, C2024S/C2025S

Promoter

polH

Available Since

Oct. 1, 2012

Availability

Industry, Academic Institutions, and Nonprofits

Enlarge
YEplac181-SOH1

Plasmid

#8623

Depositor

Jeff Strathern

Article

Malagon et al Genetics 2004 Mar;166(3):1215-27.

Insert

SOH1 (SOH1 Budding Yeast)

Expression

Bacterial and Yeast

Mutation

Wild type

Available Since

Nov. 15, 2005

Availability

Academic Institutions and Nonprofits only

Enlarge
YEplac181-RTS1

Plasmid

#8626

Depositor

Jeff Strathern

Article

Malagon et al Genetics 2004 Mar;166(3):1215-27.

Insert

RTS1 (RTS1 Budding Yeast)

Expression

Bacterial and Yeast

Mutation

Wild type

Available Since

Nov. 15, 2005

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP13905 - pAAV-AiE0441h_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN3905)

Plasmid

#199774

Purpose

enhancer AAV for expression of SYFP2 in all striatal medium spiny neurons

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Has Service

AAV PHP.eB

Insert

SYFP2

Use

AAV

Mutation

wtGFP plus mutations F46L F64L S65G S72A M153T V1…

Available Since

July 15, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12555 - pAAV-3xSP10ins-AiE0367h_3xC2-minRho-SYFP2-WPRE3-BGHpA (Alias: CN2555)

Plasmid

#191722

Purpose

AI plasmid ALIAS: AiP12555. Expression of SYFP2 (yellow fluorescent protein) in striatal medium spiny neurons

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Insert

SYFP2

Use

AAV

Mutation

none

Available Since

Feb. 1, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP15571: pAAV-AiE1426m-minBG-iCre(R297T)-BGHpA (Alias: CN5571)

Plasmid

#230877

Purpose

AiE1426m is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal Sst-Chodl interneurons

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Has Service

AAV2

Insert

iCre(R297T)

Use

AAV

Expression

Mammalian

Available Since

Jan. 29, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP15481: pAAV-AiE0140h_3xC2-minBG-iCre(R297T)-4X2C-BGHpA (Alias: CN5481)

Plasmid

#230876

Purpose

AiE0140h_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal Pvalb interneurons

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Insert

iCre(R297T)

Use

AAV

Expression

Mammalian

Available Since

Jan. 27, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12982 - pAAV-AiE0452h_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2982)

Plasmid

#191709

Purpose

AI plasmid ALIAS: AiP12982. Expression of SYFP2 (cyan fluorescent protein) in striatal indirect pathway medium spiny neurons (D2-MSNs)

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Insert

SYFP2

Use

AAV

Mutation

none

Available Since

Feb. 1, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP13781 - pAAV-AiE0452h-minBG-iCre(R297T)-BGHpA (Alias: CN3781)

Plasmid

#199777

Purpose

enhancer AAV for Cre recombinase expression in striatal indirect pathway D2-MSNs

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Has Service

AAV PHP.eB

Insert

iCre(R297T)

Use

AAV

Mutation

R297T for reduced recombinase efficiency.

Available Since

July 15, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP13779 - pAAV-AiE0779m_3xC2-minBG-iCre(R297T)-BGHpA (Alias: CN3779)

Plasmid

#199776

Purpose

enhancer AAV for Cre recombinase expression in striatal direct pathway D1-MSNs

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Has Service

AAV PHP.eB

Insert

iCre(R297T)

Use

AAV

Mutation

R297T for reduced recombinase efficiency.

Available Since

July 15, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12609 - pAAV-AiE0779m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2609)

Plasmid

#191705

Purpose

AI plasmid ALIAS: AiP12609. Expression of SYFP2 (yellow fluorescent protein) in striatal direct pathway medium spiny neurons (D1-MSNs)

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Insert

SYFP2

Use

AAV

Mutation

none

Available Since

Feb. 1, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP15043 - pAAV-AiE1419m-minBG-SYFP2-P2A-3XFLAG-10aa-H2B-WPRE3-BGHpA (Alias: CN5043)

Plasmid

#224189

Purpose

AiE1419m is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal Pvalb+/Pthlh+ neurons

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Insert

SYFP2-P2A-3XFLAG-10aa-H2B

Use

AAV

Available Since

Sept. 25, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP15578 - pAAV-AiE0780m-minBG-iCre(R297T)-BGHpA (Alias: CN5578)

Plasmid

#224200

Purpose

AiE0780m is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal D1 MSNs

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Insert

iCre(R297T)

Use

AAV

Available Since

Sept. 26, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12610 - pAAV-AiE0780m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2610)

Plasmid

#191737

Purpose

AI plasmid ALIAS: AiP12610. Expression of SYFP2 (yellow fluorescent protein) in striatal direct pathway medium spiny neurons (D1-MSNs)

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Has Service

AAV PHP.eB

Insert

SYFP2

Use

AAV

Mutation

none

Available Since

Feb. 1, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP15457 - pAAV-AiE0441h_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN5457)

Plasmid

#224198

Purpose

AiE0441h_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal MSNs

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Insert

CoChR-EGFP

Use

AAV

Available Since

Sept. 27, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP13278: pAAV-AiE0779m_3xC2-minBG-ChR2(CRC)-EYFP-WPRE3-BGHpA (Alias: CN3278)

Plasmid

#214843

Purpose

Expression of ChR2(L132C, H134R, T159C)-EYFP in striatal direct pathway medium spiny neurons (D1 MSNs)

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Insert

ChR2(L132C, H134R, T159C)-EYFP

Use

AAV

Available Since

July 15, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP14035: pAAV-AiE0452h_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4035)

Plasmid

#214853

Purpose

Expression of CoChR-EGFP in striatal indirect pathway medium spiny neurons (D2 MSNs)

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Has Service

AAV PHP.eB

Insert

CoChR-EGFP

Use

AAV

Available Since

July 15, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge

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