We narrowed to 13,316 results for: icos
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Plasmid#229435Purposeknockout of MARK2DepositorInsertsgMARK2-R-2 (MARK2 Human)
UseCRISPR and LentiviralExpressionMammalianPromoterhU6;bU6;EFSAvailable SinceDec. 18, 2024AvailabilityAcademic Institutions and Nonprofits only -
sgMARK2-R-1
Plasmid#229434Purposeknockout of MARK2DepositorInsertsgMARK2-R-1 (MARK2 Human)
UseCRISPR and LentiviralExpressionMammalianPromoterhU6;bU6;EFSAvailable SinceDec. 18, 2024AvailabilityAcademic Institutions and Nonprofits only -
HA-YAP-5D
Plasmid#229415PurposeLentiviral or overpexression of cDNADepositorInsertYAP-5D (YAP1 Human)
UseLentiviralTagsHAExpressionMammalianMutationMARK2 phosphosites (S128,S163,S350,T354,T398) mut…PromoterEFSAvailable SinceDec. 16, 2024AvailabilityAcademic Institutions and Nonprofits only -
HA-YAP-5A
Plasmid#229413PurposeLentiviral or overpexression of cDNADepositorInsertYAP-5A (YAP1 Human)
UseLentiviralTagsHAExpressionMammalianMutationMARK2 phosphosites (S128,S163,S350,T354,T398) mut…PromoterEFSAvailable SinceDec. 12, 2024AvailabilityAcademic Institutions and Nonprofits only -
pSCBE3-HF1
Plasmid#218156PurposeThis plasmid harbors the base editor SCBE3-HF1 along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing in Streptomyces.DepositorInsertsscbe3-HF1
a programmable sgRNA cloning cassette
UseCRISPR; Sgrna transcriptionExpressionBacterialMutationMutations in the portion of SpCas9 : D10A / N497A…PromoterrpsL promoterAvailable SinceMay 29, 2024AvailabilityAcademic Institutions and Nonprofits only -
pcDNA5/FRT/TO GABARAP(G116A)-mTagBFP2- GABARAP
Plasmid#212106PurposeExpression of GABARAP split tandem protein with mTagBFP2DepositorInsertGABARAP(G116A)-mTagBFP2-GABARAP (GABARAP Entacmaea quadricolor, Human)
TagsmTagBFP2ExpressionMammalianMutationG116A (lipidation deficiency) of upstream GABARAPPromoterCMVAvailable SinceMay 22, 2024AvailabilityAcademic Institutions and Nonprofits only -
pcDNA5/FRT/TO GABARAP(G116A)-mTagBFP2-GABARAP(G116A)
Plasmid#212108PurposeExpression of lipidation deficient GABARAP split tandem protein with mTagBFP2DepositorInsertGABARAP(G116A)-mTagBFP2-GABARAP(G116A) (GABARAP Entacmaea quadricolor, Human)
TagsmTagBFP2ExpressionMammalianMutationG116A (lipidation deficiency) of both GABARAPsPromoterCMVAvailable SinceMay 22, 2024AvailabilityAcademic Institutions and Nonprofits only -
pSCBE3-HF1-Hypa
Plasmid#218158PurposeThis plasmid harbors the base editor SCBE3-HF1-Hypa along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing in Streptomyces.DepositorInsertsscbe3-HF1-Hypa
a programmable sgRNA cloning cassette
UseCRISPR; Sgrna transcriptionExpressionBacterialMutationMutations in the portion of SpCas9 : D10A / N497A…PromoterrpsL promoterAvailable SinceMay 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
pSCBE3-Hypa
Plasmid#218157PurposeThis plasmid harbors the base editor SCBE3-Hypa along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing in Streptomyces.DepositorInsertsscbe3-Hypa
a programmable sgRNA cloning cassette
UseCRISPR; Sgrna transcriptionExpressionBacterialMutationMutations in the portion of SpCas9 : D10A / N692A…PromoterrpsL promoterAvailable SinceMay 10, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-DIO-GRAB_CRF0.5
Plasmid#208660PurposeExpresses the genetically-encoded fluorescent corticotropin-releasing factor (CRF) sensor GRAB_CRF0.5 in a cre-dependent mannerDepositorInsertGPCR activation based corticotropin-releasing factor (CRF) sensor GRAB_CRF0.5
UseAAVPromoterhSynAvailable SinceOct. 24, 2023AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1+FLAG-KrasnatQ61R
Plasmid#206843PurposeTo express mouse Kras encoded by native mouse codons and with a Q61R mutation with an N-terminal FLAG tag.DepositorAvailable SinceOct. 3, 2023AvailabilityAcademic Institutions and Nonprofits only -
MultiMate-PE3 HEK3
Plasmid#206273PurposeVector for the production of recombinant baculovirus using MultiMate assembly. All-in-one vector for PE3 HEK3 prime editing.DepositorInsertPE2 (synthetic), hU6 HEK3 PegRNA, hU6 HEK3 sgRNA, aeBlue (E. quadricolor), VSV-G, TagBFP
UseCRISPR; Recombinant baculovirus productionExpressionMammalianAvailable SinceSept. 27, 2023AvailabilityAcademic Institutions and Nonprofits only -
pS97splitRBP_S1dC2
Plasmid#183769PurposeExpresses SHIP1-delta-C2-Enzyme domain flanked by RBPDepositorInsertSHIP1deltaC2 (INPP5D Human)
Tags6HIS, RBP (C-terminal) w/HRV3C cleavage site, and…ExpressionBacterialMutationSHIP1deltaC2 includes aa N393 to aa Q730 onlyPromoterT7lacAvailable SinceJune 30, 2022AvailabilityAcademic Institutions and Nonprofits only -
pS97splitRBP_S1-Enz
Plasmid#183767PurposeExpresses SHIP1-Enzyme domain flanked by RBPDepositorInsertSHIP1 (INPP5D Human)
Tags6HIS, RBP (C-terminal) w/HRV3C cleavage site, and…ExpressionBacterialMutationincludes aa N393 to aa L864 onlyPromoterT7lacAvailable SinceMay 26, 2022AvailabilityAcademic Institutions and Nonprofits only -
pET24TEV-tSHIP2
Plasmid#183771PurposeExpresses C-terminal truncated SHIP2 (tSHIP2) with C-terminal TEV and 6HIS tags from pET24 backboneDepositorInsertSHIP2 (INPPL1 Human)
Tags6HIS and Tobacco Etch Virus (TEV) Cleavage siteExpressionBacterialMutationincludes aa18 to aa985 onlyPromoterT7 lacAvailable SinceMay 26, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCMV6-Entry IL36RN R48W
Plasmid#58324Purposeentry vector for human IL36RN R48W mutantDepositorInsertIL36RN (IL36RN Human)
UseEntry vectorTagsmyc-DDKMutationR48W: c.142C>T, p.Arg48TrpPromoterCMVAvailable SinceJuly 30, 2014AvailabilityAcademic Institutions and Nonprofits only -
pCMV6-Entry IL36RN P76L
Plasmid#58322Purposeentry vector for human IL36RN P76L mutantDepositorInsertIL36RN (IL36RN Human)
UseEntry vectorTagsmyc-DDKMutationP76L: c.227C>T,p.Pro76LeuPromoterCMVAvailable SinceJuly 30, 2014AvailabilityAcademic Institutions and Nonprofits only -
pCMV6-Entry IL36RN Κ35R
Plasmid#58320Purposeentry vector for human IL36RN K35R mutantDepositorInsertIL36RN (IL36RN Human)
UseEntry vectorTagsmyc-DDKMutationΚ35R: c.104A>G, p.Lys35ArgPromoterCMVAvailable SinceJuly 25, 2014AvailabilityAcademic Institutions and Nonprofits only -
pCMV5b HA Irx5 deltaIrot
Plasmid#24995DepositorInsertIrx5 (Irx5 Mouse)
TagsHAExpressionMammalianMutationDeletion of Iro box (aa 314-327), 19 aa upstream …Available SinceAug. 2, 2010AvailabilityAcademic Institutions and Nonprofits only -
pCMV5b HA Irx5 deltaC
Plasmid#24996DepositorInsertIrx5 (Irx5 Mouse)
TagsHAExpressionMammalianMutationDeletes everything after Hox Domain (aa 112-177).…Available SinceAug. 2, 2010AvailabilityAcademic Institutions and Nonprofits only