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Showing: 21 - 40 of 62 results
  1. AAV:ITR-U6-sgRNA(Kras)-U6-sgRNA(p53)-U6-sgRNA(Lkb1)-pEFS-Rluc-2A-Cre-shortPA-KrasG12D_HDRdonor-ITR (AAV-KPL)

    Plasmid
    #60224
    Purpose
    Expresses Cre recombinase and Renilla luciferase from the EFS promoter and three U6-driven sgRNAs targeting Kras, p53, and Lkb1. Contains KrasG12D HDR donor. AAV backbone.
    Depositor
    Inserts
    sgRNA
    Renilla luciferase
    Cre recombinase
    KrasG12D HDR donor (Kras Mouse)
    Use
    AAV, CRISPR, Cre/Lox, and Mouse Targeting
    Tags
    Cre-HA and Rluc-P2A
    Expression
    Mammalian
    Mutation
    Promoter
    EFS, No promoter, and U6
    Available since
    Oct. 9, 2014
    Availability
    Academic Institutions and Nonprofits only
  2. PAK4-FL-3'UTR-MT2

    Plasmid
    #113093
    Purpose
    Luciferase reporter containing PAK4-FL- 3' UTR with the second predicted MiR-199a-3p binding site mutated
    Depositor
    Insert
    p21 Activated kinase 4 (PAK4 Human)
    Use
    Luciferase
    Tags
    Expression
    Mammalian
    Mutation
    Second predicted miR-199a-3p binding site mutated…
    Promoter
    PGK
    Available since
    Aug. 17, 2018
    Availability
    Academic Institutions and Nonprofits only
  3. pMiR-HPV16-E7-m2

    Plasmid
    #53698
    Purpose
    Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
    Depositor
    Insert
    HPV16-E7
    Use
    Luciferase
    Tags
    Expression
    Mutation
    Mutation in miR-375 binding site m2 (refer to cit…
    Promoter
    Available since
    June 19, 2014
    Availability
    Academic Institutions and Nonprofits only
  4. pMiR-HPV16-E7-m1

    Plasmid
    #53697
    Purpose
    Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
    Depositor
    Insert
    HPV16-E7
    Use
    Luciferase
    Tags
    Expression
    Mutation
    Mutation in miR-375 binding site m1 (refer to cit…
    Promoter
    Available since
    June 19, 2014
    Availability
    Academic Institutions and Nonprofits only
  5. pMiR-HPV16-E1-m5

    Plasmid
    #53702
    Purpose
    Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
    Depositor
    Insert
    HPV16-E1(partial)
    Use
    Luciferase
    Tags
    Expression
    Mutation
    Mutation in miR-375 binding site m5 (refer to cit…
    Promoter
    Available since
    June 26, 2014
    Availability
    Academic Institutions and Nonprofits only
  6. pMiR-HPV16-E1-m4

    Plasmid
    #53701
    Purpose
    Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
    Depositor
    Insert
    HPV16-E1(partial)
    Use
    Luciferase
    Tags
    Expression
    Mutation
    Mutation in miR-375 binding site m4 (refer to cit…
    Promoter
    Available since
    June 26, 2014
    Availability
    Academic Institutions and Nonprofits only
  7. pMiR-HPV16-E1-m3

    Plasmid
    #53700
    Purpose
    Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
    Depositor
    Insert
    HPV16-E1(partial)
    Use
    Luciferase
    Tags
    Expression
    Mutation
    Mutation in miR-375 binding site m3 (refer to cit…
    Promoter
    Available since
    June 26, 2014
    Availability
    Academic Institutions and Nonprofits only
Showing: 21 - 40 of 62 results