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pLenti Blast GRP94 S64A V5

Plasmid

#240447

Purpose

Expresses mutant GRP94 in mammalian cells

Depositor

Michael Kastan

Article

Burrell et al Proc Natl Acad Sci U S A. 2025 Dec 30;12

Insert

GRP94 (HSP90B1 Human)

Use

Lentiviral

Tags

V5 tag and second KDEL seuence

Expression

Mammalian

Mutation

changed serine 64 to alanine

Promoter

CMV

Available Since

Feb. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti Blast GRP94 S64 D V5

Plasmid

#240448

Purpose

Expresses mutant GRP94 in mammalian cells

Depositor

Michael Kastan

Article

Burrell et al Proc Natl Acad Sci U S A. 2025 Dec 30;12

Insert

GRP94 (HSP90B1 Human)

Use

Lentiviral

Tags

V5 tag and second KDEL sequence

Expression

Mammalian

Mutation

changed serine 64 to aspartate

Promoter

CMV

Available Since

Feb. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti Blast GRP94 N62Q V5

Plasmid

#240449

Purpose

Expresses mutant GRP94 in mammalian cells

Depositor

Michael Kastan

Article

Burrell et al Proc Natl Acad Sci U S A. 2025 Dec 30;12

Insert

GRP94 (HSP90B1 Human)

Use

Lentiviral

Tags

V5 tag and second KDEL sequence

Expression

Mammalian

Mutation

changed asparagine 62 to glutamine

Promoter

CMV

Available Since

Feb. 2, 2026

Availability

Academic Institutions and Nonprofits only

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DDR1-P1

Plasmid

#236327

Purpose

Study the role and mechanism of the 3' UTR in regulating DDR1-P1 gene function.

Depositor

Angela Ting

Article

Le et al Cell Rep. 2026 Jan 13;45(1):116839. doi:

Insert

DDR1-P1 3'UTR (DDR1 Human)

Expression

Mammalian

Available Since

Jan. 20, 2026

Availability

Academic Institutions and Nonprofits only

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DDR1-P2

Plasmid

#236328

Purpose

Study the role and mechanism of the 3' UTR in regulating DDR1-P2 gene function.

Depositor

Angela Ting

Article

Le et al Cell Rep. 2026 Jan 13;45(1):116839. doi:

Insert

DDR1-P2 3'UTR (DDR1 Human)

Expression

Mammalian

Available Since

Jan. 20, 2026

Availability

Academic Institutions and Nonprofits only

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pCMV-EGFP-STIM1(238-685)

Plasmid

#248297

Purpose

An expression construct encoding an EGFP-fused STIM1 fragment (a.a.238-685).

Depositor

Sangkyu Lee

Article

Kook et al Mol Brain. 2023 Oct 17;16(1):73. doi: 10

Insert

EGFP-fused STIM1 fragment (a.a.238-685) (STIM1 )

Tags

EGFP

Expression

Mammalian

Mutation

deleted amino acids 1-237

Promoter

CMV

Available Since

Jan. 14, 2026

Availability

Academic Institutions and Nonprofits only

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pGuide-MAFA

Plasmid

#246658

Purpose

Guide RNA for human MAFA

Depositor

Joriene de Nooij

Article

Malka-Gibor et al Stem Cell Reports. 2026 Jan 2:102753. do

Insert

MAFA guide RNA (MAFA Human)

Use

CRISPR

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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pFastBac1/CALR del52-His

Plasmid

#214795

Purpose

Baculovirus expression of human CALR del52-His

Depositor

Norio Komatsu

Article

Masubuchi et al Haematologica. 2025 Nov 6. doi: 10.3324/

Insert

human CALR del52-His (CALR Human)

Tags

His

Expression

Insect

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pMSCV-IRES-GFP/CALR wtΔKDEL

Plasmid

#214791

Purpose

Mammalian expression of human CALR wtΔKDEL

Depositor

Norio Komatsu

Article

Masubuchi et al Haematologica. 2025 Nov 6. doi: 10.3324/

Insert

human CALR wtΔKDEL (CALR Human)

Use

Retroviral

Tags

non

Promoter

MSCV

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1/CALR wtΔKDEL-FLAG-KDEL

Plasmid

#214792

Purpose

Mammalian expression of human CALR wtΔKDEL-FLAG-KDEL

Depositor

Norio Komatsu

Article

Masubuchi et al Haematologica. 2025 Nov 6. doi: 10.3324/

Insert

human CALRwtΔKDEL-FLAG-KDEL (CALR Human)

Expression

Mammalian

Promoter

CMV

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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FUGW-EGFP-mHif1a-T163A

Plasmid

#242810

Purpose

Lentiviral vector expressing mouse Hif1a-T163A mutant tagged with an N-terminal EGFP

Depositor

Ronald Hart

Article

Sun et al Nat Commun. 2025 Oct 21;16(1):9312. doi:

Insert

Hypoxia-inducible factor 1, alpha subunit (Hif1a Mouse)

Use

Lentiviral

Tags

EGFP

Mutation

T163A

Promoter

Ubiquitin C

Available Since

Dec. 17, 2025

Availability

Academic Institutions and Nonprofits only

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Syntaxin1A(K264A,K265A,R210H,K84TAG)-mCherry

Plasmid

#241302

Purpose

Mammalian expression of syntaxin-1(K264A,K265A,K84TAG,R210H) fused to mCherry for genetic code expansion via Amber codon supression

Depositor

Justin Taraska

Article

Obashi et al Structure. Volume 34, Issue 1, 8 January

Insert

Syntaxin-1A (Stx1a Rat)

Tags

mCherry

Expression

Mammalian

Mutation

K264A,K265A,K84TAG,R210H

Promoter

CMV

Available Since

Dec. 11, 2025

Availability

Academic Institutions and Nonprofits only

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pX459-Lrp5 gRNA

Plasmid

#246548

Purpose

CRISPR vector co-expressing Cas9 and a mouse Lrp5 gRNA

Depositor

Mario Vallon

Article

Heiden et al J Biol Chem. 2025 Sep 4:110682. doi: 10.

Insert

Lrp5 gRNA (Lrp5 Mouse)

Use

CRISPR

Promoter

U6

Available Since

Dec. 3, 2025

Availability

Academic Institutions and Nonprofits only

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FUGW-EGFP-mHif1a-T163E

Plasmid

#242811

Purpose

Lentiviral vector expressing mouse Hif1a-T163E mutant tagged with an N-terminal EGFP

Depositor

Ronald Hart

Article

Sun et al Nat Commun. 2025 Oct 21;16(1):9312. doi:

Insert

Hypoxia-inducible factor 1, alpha subunit (Hif1a Mouse)

Use

Lentiviral

Tags

EGFP

Mutation

T163E

Promoter

Ubiquitin C

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pET-p120RasGAP-581-1047-WT

Plasmid

#246487

Purpose

Expresses C2 and GAP domains of human p120RasGAP (residues 581-1047 wild type) in E. coli

Depositor

Titus Boggon

Article

Paul et al Methods. 2025 Dec;244:108-117. doi: 10.1

Insert

RASA1 (RASA1 Human)

Tags

6His

Expression

Bacterial

Mutation

deleted amino acids 1-580

Promoter

T7lac

Available Since

Oct. 21, 2025

Availability

Academic Institutions and Nonprofits only

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L4275 hIgKLSS_hTNF in pcDNA backbone

Plasmid

#244182

Purpose

Constitutive expression of human mature TNF (with the human IgK light chain secretion sequence)

Depositor

Joshua Leonard

Article

Edelstein et al Nat Chem Biol. 2025 Aug 22:10.1038/s4158

Insert

TNF with IgK light chain secretion sequence (TNF Synthetic, Human)

Use

Synthetic Biology

Expression

Mammalian

Promoter

CMV

Available Since

Oct. 16, 2025

Availability

Academic Institutions and Nonprofits only

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pCAG coca-5HT3-IRES-GFP

Plasmid

#242193

Purpose

Expression vector for cocaine-gated chemogenetic cation channel

Depositor

Scott Sternson

Article

Gomez et al Nature. 2025 Aug 27. doi: 10.1038/s41586

Insert

coca-5HT3-IRES-GFP (Htr3a Mouse)

Expression

Mammalian

Mutation

L141G G175K Y210F Y217F

Promoter

CAG

Available Since

Oct. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pZac2.1-GfaABC1D-2xEzrin-BioID2-HA

Plasmid

#227681

Purpose

To over express 2x Ezrin under gfaABC1D promoter in astrocytes

Depositor

Cagla Eroglu

Article

Wang et al eLife 2025 [Reviewed Preprint] 14:RP1075

Insert

2x Ezrin (Ezr Mouse)

Tags

BioID2-HA

Expression

Mammalian

Available Since

Oct. 1, 2025

Availability

Academic Institutions and Nonprofits only

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PKT2/CLP-Aoah

Plasmid

#239612

Purpose

Expresses mouse Aoah protein in the transposon vector

Depositor

Xin-yuan Guan

Article

Gong et al Cell. 2025 Jul 24:S0092-8674(25)00793-7.

Insert

Acyloxyacyl Hydrolase (Aoah Mouse)

Use

Transposon

Tags

HA

Expression

Mammalian

Available Since

Aug. 15, 2025

Availability

Academic Institutions and Nonprofits only

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GST-GRP78-N Terminus (pGEX4T1)

Plasmid

#238422

Purpose

Expresses GRP78 N terminus fused to the GST Tag

Depositor

Amy Shiu Lee

Article

Tseng et al Neoplasia. 2019 Aug;21(8):837-848. doi:

Insert

78-kDa glucose-regulated protein (HSPA5 Human)

Tags

GST

Expression

Bacterial

Available Since

Aug. 7, 2025

Availability

Academic Institutions and Nonprofits only

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