We narrowed to 537 results for: gcg.2

1. pX330A-Yap1-E2-#1

   Plasmid

   #171518

   Purpose

   deletion of a genomic locus in Yap1 gene

   Depositor

   Hans Schöler

   Article

   Kagiwada et al Development. 2021 Oct 15;148(20). pii: 2

   Insert

   Yap1 (Yap1 Mouse)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Nov. 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pSUPER-retro-puro-Smad3

   Plasmid

   #89828

   Purpose

   Knockdown human Smad3 expression in human mammalian cells

   Depositor

   Shengyu Yang

   Article

   Sun et al J Biol Chem. 2011 Nov 11;286(45):38865-7

   Insert

   SMAD3 shRNA (SMAD3 Human)
   

   Use

   Retroviral

   Available Since

   May 10, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. LENTICRISPR-PGM2_sgRNA2

   Plasmid

   #201617

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Article

   Skinner et al Nat Metab. 2023 May;5(5):765-776. doi: 1

   Insert

   PGM2 (PGM2 Human)
   

   Use

   CRISPR and Lentiviral

   Available Since

   July 26, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. LENTICRISPR-TYMS_sgRNA2

   Plasmid

   #201629

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Article

   Skinner et al Nat Metab. 2023 May;5(5):765-776. doi: 1

   Insert

   TYMS (TYMS Human)
   

   Use

   CRISPR and Lentiviral

   Available Since

   June 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pGMC00007

   Plasmid

   #166725

   Purpose

   non targeting sgRNA

   Depositor

   Raj Chari

   Article

   Ruiz-Rodado et al Cancer Metab. 2020 Oct 21;8:23. doi: 10.

   Insert

   Non-targeting guide
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   June 9, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. sg_Gemin2_i1-ipUSEPR-TR657

   Plasmid

   #228919

   Purpose

   Knockdown of Gemin2 in mammalian cells

   Depositor

   Sika Zheng

   Article

   Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

   Insert

   sg_Gemin2_i1 (Gemin2 Mouse)
   

   Use

   Lentiviral

   Available Since

   Jan. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. PFKFB3 gRNA (BRDN0001146230)

   Plasmid

   #76462

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PFKFB3

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PFKFB3 (PFKFB3 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. SIK2 gRNA (BRDN0001149208)

   Plasmid

   #77138

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human SIK2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   SIK2 (SIK2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. PKN2 gRNA (BRDN0001147750)

   Plasmid

   #77926

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PKN2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PKN2 (PKN2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 5, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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10. pFB-U6-Chrna2-gRNA-hSyn-mCherry-WPRE-SV40pA

    Plasmid

    #128337

    Purpose

    pAAV encoding gRNA sequence for loss-of-function indels

    Depositor

    Ryan Drenan

    Article

    Peng et al Eur J Neurosci. 2018 May 19. doi: 10.111

    Insert

    Chrna2 (Chrna2 Mouse)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    July 19, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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11. pURD214

    Plasmid

    #113871

    Purpose

    expression of Cas9 programming sgRNA5 and sgRNA2 targetting HXT13-15-16 and HXT2 respectively

    Depositor

    Jack Pronk, Jean-Marc Daran

    Article

    Wijsman et al FEMS Yeast Res. 2019 Jan 1;19(1). pii: 5

    Insert

    sgRNA5 HXT13-15-16 sgRNA2-HXT2
    

    Use

    CRISPR

    Expression

    Yeast

    Available Since

    Sept. 5, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. pIS1-mutant RhoA 3'UTR

    Plasmid

    #26090

    Depositor

    Bob Weinberg

    Article

    Valastyan et al Cell. 2009 Jun 12. 137(6):1032-46.

    Insert

    mutant RhoA 3'UTR (RHOA Human)
    

    Use

    Luciferase

    Expression

    Mammalian

    Mutation

    Both miR-31 binding sites in 3’ UTR mutagenized. …

    Available Since

    Oct. 25, 2010

    Availability

    Academic Institutions and Nonprofits only

13. TAOK1 gRNA (BRDN0001148505)

    Plasmid

    #76806

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TAOK1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TAOK1 (TAOK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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14. pX330_SAFBgRNA9

    Plasmid

    #196108

    Purpose

    Contains guide RNA to 3' end of mouse SAFB gene for safb1/2 dko. Used with Addgene IDs: 196103, 196106, 196107

    Depositor

    Mauro Calabrese

    Article

    Cherney et al RNA. 2023 Jul 19:rna.079569.122. doi: 10

    Insert

    SAFB (Safb Mouse)
    

    Use

    CRISPR and Mouse Targeting

    Expression

    Bacterial and Mammalian

    Available Since

    Sept. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. TRIB1 gRNA (BRDN0001162480)

    Plasmid

    #76662

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TRIB1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TRIB1 (TRIB1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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16. PIK3R5 gRNA (BRDN0001146332)

    Plasmid

    #75759

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PIK3R5

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PIK3R5 (PIK3R5 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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17. PIK3R5 gRNA (BRDN0001146461)

    Plasmid

    #75760

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PIK3R5

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PIK3R5 (PIK3R5 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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18. pPU-huMDA5-miR30-L1221

    Plasmid

    #174223

    Purpose

    All-in-one huMDA5 rescue-control shRNA knockdown vector

    Depositor

    Jeremy Luban

    Article

    Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

    Insert

    MDA5 (IFIH1 Human)
    

    Use

    Lentiviral and RNAi

    Expression

    Mammalian

    Promoter

    SFFV

    Available Since

    Aug. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. UCK2_Deletion_gRNA_1

    Plasmid

    #204672

    Purpose

    Dual gRNA plasmid for UCK2 deletion

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    uridine-cytidine kinase 2 (UCK2 Human)
    

    Use

    Lentiviral

    Promoter

    U6

    Available Since

    March 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. Akaby

    Bacterial Strain

    #184224

    Purpose

    Akaby is a RecB knockout E. coli strain, made for cell-free expression system for linear templates.

    Depositor

    Kate Adamala

    Article

    Sato et al PLoS One. 2022 Apr 7;17(4):e0266272. doi

    Bacterial Resistance

    Kanamycin

    Available Since

    May 16, 2022

    Availability

    Academic Institutions and Nonprofits only