We narrowed to 7,663 results for: ski

1. LENTICRISPR-LUC7L_sgRNA2

   Plasmid

   #201601

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Article

   Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

   Insert

   LUC7L (LUC7L Human)
   

   Use

   CRISPR and Lentiviral

   Available Since

   June 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. LENTICRISPR-LUC7L3_sgRNA1

   Plasmid

   #201604

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Article

   Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

   Insert

   LUC7L3 (LUC7L3 Human)
   

   Use

   CRISPR and Lentiviral

   Available Since

   June 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. LENTICRISPR-LUC7L3_sgRNA2

   Plasmid

   #201605

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Article

   Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

   Insert

   LUC7L3 (LUC7L3 Human)
   

   Use

   CRISPR and Lentiviral

   Available Since

   June 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. LENTICRISPR-PABPC1_sgRNA2

   Plasmid

   #201609

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Article

   Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

   Insert

   PABPC1 (PABPC1 Human)
   

   Use

   CRISPR and Lentiviral

   Available Since

   June 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. Halo-H1DBD-H2

   Plasmid

   #200205

   Purpose

   Expression of HSF2 with HSF1 DBD

   Depositor

   Sheila Teves

   Article

   Price et al Nucleic Acids Res. 2023 Apr 28:gkad304.

   Insert

   Halo-H1DBD-H2 (Hsf1, Hsf2 Mouse)
   

   Tags

   Halo

   Expression

   Mammalian

   Mutation

   HSF1 (1-399); HSF2 (366-1554)

   Promoter

   EF_1alpha

   Available Since

   May 17, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. H2DBD-H1-Halo

   Plasmid

   #200193

   Purpose

   Expression of HSF1 with HSF2 DBD

   Depositor

   Sheila Teves

   Article

   Price et al Nucleic Acids Res. 2023 Apr 28:gkad304.

   Insert

   H2DBD-H1-Halo (Hsf1, Hsf2 Mouse)
   

   Tags

   Halo

   Expression

   Mammalian

   Mutation

   HSF2 (1-366); HSF1 (399-1576)

   Promoter

   EF_1alpha

   Available Since

   May 17, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pGL3-pSMANTIS_SMAD-FOS_Mutant

   Plasmid

   #194188

   Purpose

   Includes the promoter (1kb) of SMTS with mutated SMAD/FOS binding site

   Depositor

   Ralf Brandes, Matthias Leisegang

   Article

   Leisegang et al Eur Heart J. 2019 Aug 7;40(30):2523-2533

   Insert

   SMANTIS promoter (1kb) (SMANTIS Human)
   

   Use

   Luciferase

   Mutation

   mutated SMAD/FOS Site, Region 3-15nt of 1000nt

   Promoter

   SMANTIS promoter (1kb), mutated

   Available Since

   Jan. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pGL3-pSMANTIS_STAT1-2_Mutant

   Plasmid

   #194189

   Purpose

   Includes the promoter (1kb) of SMTS with mutated STAT1/2 binding site

   Depositor

   Ralf Brandes, Matthias Leisegang

   Article

   Leisegang et al Eur Heart J. 2019 Aug 7;40(30):2523-2533

   Insert

   SMANTIS promoter (1kb) (SMANTIS Human)
   

   Use

   Luciferase

   Mutation

   mutated STAT1/2 site, Region 653-673nt of 1000nt

   Promoter

   SMANTIS promoter (1kb), mutated

   Available Since

   Jan. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pMXs-Sox2AV

   Plasmid

   #193354

   Purpose

   Retroviral vector expressing mouse Sox2A61V point mutant

   Depositor

   Hans Schöler

   Article

   MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

   Insert

   Sox2AV (Sox2 Mouse)
   

   Use

   Retroviral

   Expression

   Mammalian

   Mutation

   Sox2A61V is a highly cooperative point mutant of …

   Promoter

   5'LTR

   Available Since

   Dec. 15, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. pMXs-hSOX2AV

    Plasmid

    #193352

    Purpose

    Retroviral vector expressing human SOX2A61V point mutant

    Depositor

    Hans Schöler

    Article

    MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

    Insert

    SOX2AV (SOX2 Human)
    

    Use

    Retroviral

    Expression

    Mammalian

    Mutation

    SOX2A61V is a highly cooperative point mutant of …

    Promoter

    5'LTR

    Available Since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. W118-1_hZBTB7B_R363L

    Plasmid

    #180381

    Purpose

    lentiviral transduction of human ZBTB7B gene with a point mutation (R363L) in the first ZF domain

    Depositor

    Huda Zoghbi

    Article

    Lee et al EMBO J. 2021 Apr 1;40(7):e106106. doi: 1

    Insert

    ZBTB7B_R363L (ZBTB7B Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    R363L

    Promoter

    CMV

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. W118-1_hZBTB7B_D35N_R49Q

    Plasmid

    #180383

    Purpose

    lentiviral transduction of human ZBTB7B gene with point mutations (D35N and R49Q) in the BTB domain

    Depositor

    Huda Zoghbi

    Article

    Lee et al EMBO J. 2021 Apr 1;40(7):e106106. doi: 1

    Insert

    ZBTB7B_D35N/R49Q (ZBTB7B Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    D35N/R49Q

    Promoter

    CMV

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. W118-1_hZBTB7B_R49H

    Plasmid

    #180382

    Purpose

    lentiviral transduction of human ZBTB7B gene with a point mutation (R49H) in the BTB domain

    Depositor

    Huda Zoghbi

    Article

    Lee et al EMBO J. 2021 Apr 1;40(7):e106106. doi: 1

    Insert

    ZBTB7B_R49H (ZBTB7B Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    R49H

    Promoter

    CMV

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. AAV.CBA.YFP.miR-E_shIrak1-2

    Plasmid

    #180398

    Purpose

    Producing AAV that encodes mouse Irak1 shRNA-2 with miR-E backbone

    Depositor

    Huda Zoghbi

    Article

    Lee et al J Clin Invest. 2022 May 2;132(9). pii: 1

    Insert

    shIrak1-2 (Irak1 Mouse)
    

    Use

    AAV and RNAi

    Promoter

    CBA

    Available Since

    Nov. 2, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. AAV.CBA.YFP.miR-E_shIrak1-3

    Plasmid

    #180399

    Purpose

    Producing AAV that encodes mouse Irak1 shRNA-3 with miR-E backbone

    Depositor

    Huda Zoghbi

    Article

    Lee et al J Clin Invest. 2022 May 2;132(9). pii: 1

    Insert

    shIrak1-3 (Irak1 Mouse)
    

    Use

    AAV and RNAi

    Promoter

    CBA

    Available Since

    Nov. 2, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. AAV.CBA.YFP.miR-E_shIrak1-1

    Plasmid

    #180397

    Purpose

    Producing AAV that encodes mouse Irak1 shRNA-1 with miR-E backbone

    Depositor

    Huda Zoghbi

    Article

    Lee et al J Clin Invest. 2022 May 2;132(9). pii: 1

    Insert

    shIrak1-1 (Irak1 Mouse)
    

    Use

    AAV and RNAi

    Promoter

    CBA

    Available Since

    Nov. 2, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pJET-osr1-KI-donor

    Plasmid

    #184875

    Purpose

    Donor template for knock-in of p2a-CreERT2 into the medaka osr1 locus via CRISPR/Cas9-mediated homology directed repair

    Depositor

    Christoph Winkler

    Article

    Hui et al Development. 2022 May 20. pii: 275483. d

    Inserts

    Odd-Skipped Related Transcription Factor 1 5' homology arm
    Odd-Skipped Related Transcription Factor 1 3' homology arm
    p2a-CreERT2
    Myosin light chain 2 promoter
    EGFP
    

    Use

    CRISPR and Cre/Lox

    Available Since

    July 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. pFUGW-shRIIα-RIIαS97A-IRES-EGFP

    Plasmid

    #183457

    Purpose

    Replacement of endogenous rat PKA-RIIα subunits with the RIIα S97A variant

    Depositor

    Matthew Gold

    Article

    Church et al Elife. 2021 Oct 6;10. pii: 68164. doi: 1

    Insert

    sgRNA and Prkar2a (Prkar2a Rat)
    

    Use

    Lentiviral

    Mutation

    shRNA-resistant mutations: C135>G, G138>A, …

    Promoter

    shRNA: H1 / gene: ubiquitin

    Available Since

    June 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pFUGW-shRIIα-RIIαS97E-IRES-EGFP

    Plasmid

    #183458

    Purpose

    Replacement of endogenous rat PKA-RIIα subunits with the RIIα S97E variant

    Depositor

    Matthew Gold

    Article

    Church et al Elife. 2021 Oct 6;10. pii: 68164. doi: 1

    Insert

    sgRNA and Prkar2a (Prkar2a Rat)
    

    Use

    Lentiviral

    Mutation

    shRNA-resistant mutations: C135>G, G138>A, …

    Promoter

    shRNA: H1 / gene: ubiquitin

    Available Since

    June 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. AAV.CBA.YFP.miR-E_shRps6ka2-3

    Plasmid

    #180390

    Purpose

    Producing AAV that encodes mouse Rps6ka2 (Rsk3) shRNA-3 with miR-E backbone

    Depositor

    Huda Zoghbi

    Article

    Lee et al EMBO J. 2021 Apr 1;40(7):e106106. doi: 1

    Insert

    shRps6ka2-3 (Rps6ka2 Mouse)
    

    Use

    AAV and RNAi

    Promoter

    CBA

    Available Since

    Feb. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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