We narrowed to 635 results for: PK1

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DNA-PKcs T3950D

Plasmid

#83320

Purpose

DNA-PKcs T3950A

Depositor

Katheryn Meek

Article

Douglas et al Mol Cell Biol. 2007 Mar;27(5):1581-91. E

Insert

human DNA-PKcs (PRKDC Human)

Expression

Mammalian

Mutation

Activation loop phosphorylation site 3950 substit…

Available Since

Aug. 8, 2017

Availability

Academic Institutions and Nonprofits only

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pUC19-U6-[BsmBI_pegRNA_entry]-tevopreQ1-term (LM1138)

Plasmid

#223137

Purpose

pU6 entry plamid for cloning prime editor tevopreQ1 epegRNAs (requires BsmBI or Esp3I digest and ligation of duplexed oligos)

Depositor

Benjamin Kleinstiver

Article

Silverstein et al Nature. 2025 Apr 22. doi: 10.1038/s41586

Insert

etevopreQ1 entry plasmid backbone for epegRNA expression via human U6 promoter

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

April 23, 2025

Availability

Academic Institutions and Nonprofits only

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MAPK9 gRNA (BRDN0001146002)

Plasmid

#76719

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK9

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK9 (MAPK9 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAPK9 gRNA (BRDN0001147687)

Plasmid

#76720

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK9

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK9 (MAPK9 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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W118-1_hRSK3(RPS6KA2)_K91A_K444A

Plasmid

#180385

Purpose

lentiviral transduction of human RSK3 (RPS6KA2) gene with point mutations (K91A and K444A) that inactivate kinase activity

Depositor

Huda Zoghbi

Article

Lee et al EMBO J. 2021 Apr 1;40(7):e106106. doi: 1

Insert

RPS6KA2_K91A/K444A (RPS6KA2 Human)

Use

Lentiviral

Expression

Mammalian

Mutation

K91A/K444A

Promoter

CMV

Available Since

Feb. 9, 2022

Availability

Academic Institutions and Nonprofits only

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MAPK9 gRNA (BRDN0001147698)

Plasmid

#76718

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK9

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK9 (MAPK9 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IPPK gRNA (BRDN0001145851)

Plasmid

#77151

Purpose

3rd generation lentiviral gRNA plasmid targeting human IPPK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IPPK (IPPK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IPPK gRNA (BRDN0001146016)

Plasmid

#77152

Purpose

3rd generation lentiviral gRNA plasmid targeting human IPPK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IPPK (IPPK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IPPK gRNA (BRDN0001147080)

Plasmid

#77153

Purpose

3rd generation lentiviral gRNA plasmid targeting human IPPK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IPPK (IPPK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IPPK gRNA (BRDN0001148440)

Plasmid

#77154

Purpose

3rd generation lentiviral gRNA plasmid targeting human IPPK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IPPK (IPPK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IP6K1 gRNA (BRDN0001147847)

Plasmid

#76135

Purpose

3rd generation lentiviral gRNA plasmid targeting human IP6K1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IP6K1 (IP6K1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IP6K1 gRNA (BRDN0001149166)

Plasmid

#76136

Purpose

3rd generation lentiviral gRNA plasmid targeting human IP6K1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IP6K1 (IP6K1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IP6K1 gRNA (BRDN0001148869)

Plasmid

#76137

Purpose

3rd generation lentiviral gRNA plasmid targeting human IP6K1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IP6K1 (IP6K1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IP6K1 gRNA (BRDN0001146092)

Plasmid

#76138

Purpose

3rd generation lentiviral gRNA plasmid targeting human IP6K1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IP6K1 (IP6K1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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RMCE halo-flag DNA-PKcs

Plasmid

#233918

Purpose

Low copy number provides expression of human DNA-PKcs with an N-terminal halo-flag tag.

Depositor

Katheryn Meek

Article

Buehl et al Mol Cell. 2023 Mar 2;83(5):698-714.e4. d

Insert

human DNA-PKcs (PRKDC Human)

Tags

flag-halo

Expression

Mammalian

Available Since

May 12, 2025

Availability

Academic Institutions and Nonprofits only

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RMCE K>R DNA-PKcs

Plasmid

#233917

Purpose

Low copy number provides expression of human DNA-PKcs with a single K>R substitution that ablates kinase activity.

Depositor

Katheryn Meek

Article

Buehl et al Mol Cell. 2023 Mar 2;83(5):698-714.e4. d

Insert

human DNA-PKcs kinase inactive mutant K3753>R (PRKDC Human)

Expression

Mammalian

Mutation

K3753R

Available Since

May 12, 2025

Availability

Academic Institutions and Nonprofits only

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pDONR223-RPS6KC1

Plasmid

#23460

Depositor

William Hahn, David Root

Article

Johannessen et al Nature. 2010 Dec 16;468(7326):968-72. do

Insert

RPS6KC1 (RPS6KC1 Human)

Use

Gateway donor vector

Available Since

July 30, 2010

Availability

Academic Institutions and Nonprofits only
pBabe-Puro-MEK-DD

Plasmid

#15268

Depositor

William Hahn

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

Map2k1 (Mapk1 Mouse)

Use

Retroviral

Expression

Mammalian

Mutation

S218D S222D

Available Since

July 12, 2007

Availability

Academic Institutions and Nonprofits only

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RMCE wild type DNA-PKcs

Plasmid

#233911

Purpose

Low copy number provides expression of human DNA-PKcs

Depositor

Katheryn Meek

Article

Buehl et al Mol Cell. 2023 Mar 2;83(5):698-714.e4. d

Insert

dna-pkcs cDNA (PRKDC Human)

Expression

Mammalian

Available Since

April 9, 2025

Availability

Academic Institutions and Nonprofits only

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pCDNA3 Flag MKK7B2Jnk2a2

Plasmid

#19727

Depositor

Roger Davis

Article

Lei et al Mol Cell Biol. 2002 Jul . 22(13):4929-42

Insert

pCDNA3 FlagMKK7B2Jnk2a2 (MAPK9, Map2k7 Mouse, Human)

Tags

Flag

Expression

Mammalian

Available Since

March 31, 2009

Availability

Academic Institutions and Nonprofits only