167,468 results

1. Untagged TDP-43

   Plasmid

   #237551

   Purpose

   Expression of untagged wild-type TDP-43

   Depositor

   Tatyana Shelkovnikova

   Insert

   TDP-43 WT (TARDBP Human)
   

   Expression

   Mammalian

   Mutation

   wild-type TDP-43

   Promoter

   CMV

   Available Since

   May 13, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. TFORF0781

   Plasmid

   #143730

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   ZNF93 (ZNF93 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   May 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. 10279-M30-663

   Plasmid

   #225663

   Purpose

   Lentivirus protein expression. Matched control construct for 8522-M31-663 (Addgene # 225661) gives basal expression from mCMVp for gating/thresholding

   Depositor

   Dominic Esposito

   Article

   Tang et al Stem Cell Reports. 2015 Jan 13;4(1):155-

   Insert

   dsCherry
   

   Use

   Lentiviral

   Promoter

   mCMVp

   Available Since

   Jan. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLenti-HA-L2HGDH(opt)-FLAG

   Plasmid

   #230089

   Purpose

   expressing human L2HGDH

   Depositor

   Xingguo Zhu

   Article

   Xi et al Commun Biol. 2025 Jan 6;8(1):15. doi: 10

   Insert

   L2HGDH (L2HGDH Human)
   

   Use

   Lentiviral

   Tags

   FLAG and HA

   Expression

   Mammalian

   Mutation

   Multiple wobble mutations

   Promoter

   CMV

   Available Since

   Jan. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pPICZ A-Strep-Opa1 (SB251)

   Plasmid

   #227600

   Purpose

   Inducible expression of Strep-tagged Opa1 in Pichia pastoris

   Depositor

   Luke Chao

   Article

   Boopathy et al J Biol Chem. 2024 Aug 31:107740. doi: 10

   Insert

   OPA1 (OPA1 Human)
   

   Tags

   Twin-StrepTag

   Expression

   Yeast

   Mutation

   contains aa 253-960 only

   Promoter

   AOX1

   Available Since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCAG-TSF-TBK1

   Plasmid

   #216709

   Purpose

   Mammalian expression of TBK1

   Depositor

   James Hurley

   Article

   Tudorica et al J Cell Biol. 2024 Jul 1;223(7):e20230901

   Insert

   TBK1 (TBK1 Human)
   

   Tags

   TSF

   Expression

   Mammalian

   Available Since

   Nov. 7, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pDRF1 ymScarletI3_T2A_mTurquoise2

   Plasmid

   #219829

   Purpose

   equimolar expression of ymScarletI3 and mTurquoise2 in budding yeast

   Depositor

   Bas Teusink

   Article

   Botman et al bioRxiv 2025.06.27.661975; doi: https://

   Insert

   ymScarletI3_T2A_mTurquoise2
   

   Expression

   Yeast

   Available Since

   Aug. 27, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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8. CCM2(FL)_pET49b

   Plasmid

   #224066

   Purpose

   Bacterial expression of full-length CCM2 fused to an N-terminal GST. HRV-3C cleavage site

   Depositor

   Ben Goult

   Article

   Ball et al J Cell Biol. 2024 Sep 2;223(9):e20231003

   Insert

   ccm2 (CCM2 Human)
   

   Tags

   GST; 6xHIS

   Expression

   Bacterial

   Promoter

   T7

   Available Since

   Aug. 26, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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9. pTEF1_MS2

   Plasmid

   #220625

   Purpose

   Source for TEF1 MS2 coat fusion protein fusion

   Depositor

   Marvin Wickens

   Article

   Preston et al Nat Methods. 2019 May;16(5):437-445. doi

   Type

   Empty backbone

   Expression

   Yeast

   Available Since

   June 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pL6-H2B-iRFP720-bla

    Plasmid

    #189991

    Purpose

    Lentivirial plasmid for nuclear iRFP-720 expression with blasticidin resistance

    Depositor

    Achim Kramer

    Article

    Gabriel et al Proc Natl Acad Sci U S A. 2024 Aug 20;12

    Insert

    Human histone H2B
    

    Use

    Lentiviral

    Tags

    iRFP720

    Expression

    Mammalian

    Available Since

    Feb. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pMM7

    Plasmid

    #201213

    Purpose

    Integrative GFP-based shuttle vector for genetic engineering of Parageobacillus thermoglucosidasius. Carries homologous flanks for deletion of key sporulation regulator spo0A.

    Depositor

    Alex Nielsen

    Article

    Millgaard et al AMB Express. 2023 May 8;13(1):44. doi: 1

    Inserts

    sfGFP
    Spo0A right flank
    Spo0A left flank
    

    Use

    Synthetic Biology

    Expression

    Bacterial

    Mutation

    F11V, T13P, N39D, A179A

    Available Since

    Aug. 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. TFORF2894

    Plasmid

    #144190

    Purpose

    Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Insert

    MTA1 (MTA1 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    Aug. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. ND6-L1397-N_UGI-NES_right

    Plasmid

    #187846

    Purpose

    expresses the right-side half ND6-UGI-NES in mammalian cells

    Depositor

    Chengqi Yi

    Article

    Lei et al Nature. 2022 May 12. pii: 10.1038/s41586

    Insert

    COX8A MTS–3xFLAG–ND6 right TALE–G1397 DddA-C–UGI–NES–ATP5B 3'UTR
    

    Expression

    Mammalian

    Available Since

    Oct. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. ND6-L1397-N_UGI-NES_left

    Plasmid

    #187845

    Purpose

    expresses the left-side half ND6-UGI-NES in mammalian cells

    Depositor

    Chengqi Yi

    Article

    Lei et al Nature. 2022 May 12. pii: 10.1038/s41586

    Insert

    SOD2 MTS–3x-HA–ND6 left tale–G1397 DddA-N–UGI–hivNES–SOD2 3'UTR
    

    Expression

    Mammalian

    Available Since

    Oct. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. pRS416-PTEF1-MCP-no_intron

    Plasmid

    #127597

    Purpose

    low-copy URA-selectable plasmid, 1xFLAG-MCP under TEF1 promoter

    Depositor

    David Bartel

    Article

    Morgan et al Nature. 2019 Jan;565(7741):606-611. doi:

    Insert

    1xFLAG-MCP expression cassette
    

    Expression

    Yeast

    Available Since

    April 9, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. pET28a(+)/FbGH17B

    Plasmid

    #100912

    Purpose

    Expression of the Beta-1,3-Exo-Laminarinase FbGH17B in E.coli

    Depositor

    Jan-Hendrik Hehemann

    Insert

    FbGH17Bcat
    

    Tags

    His-Tag

    Expression

    Bacterial

    Mutation

    not full length

    Available Since

    April 1, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. pTK-EdnrbE1-Citrine

    Plasmid

    #127773

    Purpose

    Enhancer reporter construct containing the chicken EdnrB enhancer E1 driving Citrine activity

    Depositor

    Tatjana Sauka-Spengler

    Article

    Ling et al Nat Cell Biol. 2019 Dec;21(12):1504-1517

    Insert

    ednrbE1
    

    Use

    Enhancer reporter construct

    Available Since

    Jan. 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. lentiGuide-Puro

    Plasmid

    #52963

    Purpose

    Expresses S. pyogenes CRISPR chimeric RNA element with customizable sgRNA from U6 promoter and puromycin resistance from EF-1a promoter. 3rd generation lentiviral backbone.

    Depositor

    Feng Zhang

    Article

    Sanjana et al Nat Methods. 2014 Aug;11(8):783-4. doi:

    Has Service

    Cloning Grade DNA

    Inserts

    S. pyogenes sgRNA cassette
    Puromycin resistance
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    Ef1-a and hU6

    Available Since

    May 8, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV-hSyn-EGFP (AAV9)

    Viral Prep

    #50465-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSyn-EGFP (#50465). In addition to the viral particles, you will also receive purified pAAV-hSyn-EGFP plasmid DNA. hSyn-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    EGFP

    Available Since

    May 28, 2019

    Availability

    Academic Institutions and Nonprofits only

20. pAAV.CAG.Flex.GCaMP6s.WPRE.SV40 (AAV9)

    Viral Prep

    #100842-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.CAG.Flex.GCaMP6s.WPRE.SV40 (#100842). In addition to the viral particles, you will also receive purified pAAV.CAG.Flex.GCaMP6s.WPRE.SV40 plasmid DNA. CAG-driven, Cre-dependent GCaMP6s calcium sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Chen et al Nature. 2013 Jul 18;499(7458):295-300. d

    Promoter

    CAG

    Available Since

    May 14, 2018

    Availability

    Academic Institutions and Nonprofits only