We narrowed to 11,521 results for: AGA

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pLV-puro-EF1A-Tag100-hASB8

Plasmid

#242460

Purpose

Expresses human ASB8 protein with an N-terminal Tag100 along with a puromycin selection marker.

Depositor

Dirk Daelemans

Article

Wing et al Nat Chem Biol. 2025 Dec;21(12):2002-2013

Insert

ASB8 (ASB8 Human)

Use

Lentiviral

Tags

Tag100

Expression

Mammalian

Promoter

EF1A

Available Since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pLV-puro-EF1A-3XFLAG-hASB8

Plasmid

#242464

Purpose

Expresses human ASB8 protein with an N-terminal 3xFLAG tag along with a puromycin selection marker.

Depositor

Dirk Daelemans

Article

Wing et al Nat Chem Biol. 2025 Dec;21(12):2002-2013

Insert

ASB8 (ASB8 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Promoter

EF1A

Available Since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA18-4

Plasmid

#248546

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA18-4

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Nov. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-gRNA9-1

Plasmid

#248533

Purpose

A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Depositor

Teresa Davoli

Article

Bosco et al Cell. 2023 Apr 27;186(9):1985-2001.e19.

Insert

gRNA9-1

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Nov. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hTNF_2b)-PGKpuro2ABFP-W

Plasmid

#208426

Purpose

Lentiviral gRNA plasmid targeting human TNF gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

TNF (TNF Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-HP1a-gRNA-2

Plasmid

#237635

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HP1a gRNA (CBX5 Human)

Use

CRISPR

Tags

mCherry

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_mEGFP-SS18-SSX1-KS

Plasmid

#237679

Purpose

For overexpression of mEGFP-SS18-SSX1-KS

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

SS18-SSX1-KS (SS18, SSX1 Human)

Tags

mEGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRK5_mEGFP-SS18-SSX2-KS

Plasmid

#237680

Purpose

For overexpression of mEGFP-SS18-SSX2-KS

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

SS18-SSX2-KS (SS18, SSX2 Human)

Tags

mEGFP

Expression

Mammalian

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-HP1a-gRNA-1

Plasmid

#237634

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HP1a gRNA (CBX5 Human)

Use

CRISPR

Tags

mCherry

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-TCOF1-gRNA

Plasmid

#237633

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to TCOF1 locus

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

TCOF1 gRNA (TCOF1 Human)

Use

CRISPR

Tags

mCherry

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pUC19_msfGFP-FUS-repair-tempate

Plasmid

#237684

Purpose

For knock-in msfGFP to FUS locus

Depositor

Denes Hnisz

Article

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

FUS (FUS Human)

Use

CRISPR

Tags

msfGFP

Available Since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pRP.ATM c.7865C>T

Plasmid

#226554

Purpose

Minigene encoding the ATM c.7865C>T mutation

Depositor

Dave Wee

Article

Tabaglio et al Mol Ther Nucleic Acids. 2025 Jan 7;36(1)

Insert

ATM (ATM Human)

Tags

3xFLAG

Expression

Mammalian

Mutation

c.7865C>T

Available Since

Jan. 13, 2025

Availability

Academic Institutions and Nonprofits only

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Lenti-SAM-Puro

Plasmid

#198713

Purpose

For expression of guide RNAs and the SAM transcriptional activator for CRISPRa in mammalian cells.

Depositor

Tyler Jacks

Article

Gaglia et al Cancer Cell. 2023 May 8;41(5):871-886.e1

Inserts

U6-MS2-gRNAscaffold
EF1a-MPH-Puro

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

EF1a and U6

Available Since

Jan. 7, 2025

Availability

Academic Institutions and Nonprofits only

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Lenti-SAM-Cre

Plasmid

#198714

Purpose

For expression of guide RNAs, the SAM transcriptional activator for CRISPRa and Cre in mammalian cells

Depositor

Tyler Jacks

Article

Gaglia et al Cancer Cell. 2023 May 8;41(5):871-886.e1

Inserts

U6-MS2-gRNAscaffold
Pgk-MPH-Cre

Use

Cre/Lox and Lentiviral

Expression

Mammalian

Promoter

Pgk and U6

Available Since

Jan. 7, 2025

Availability

Academic Institutions and Nonprofits only

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hTln1-R12DD-SCLS

Plasmid

#191443

Purpose

expresses a variant of human talin1 domains R12-DD, with a deletion between K2375 and A2397

Depositor

Ben Goult

Article

Elefant et al JCI Insight. 2024 Dec 20;9(24):e173664.

Insert

Human Talin1 R12DD (TLN1 Human)

Tags

His-tag, TEV cleavage site

Expression

Bacterial

Mutation

deletion between residues K2375 and A2397

Available Since

Dec. 20, 2024

Availability

Academic Institutions and Nonprofits only

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pLX304-BCL-XL-F97W

Plasmid

#203572

Purpose

Expresses V5-tagged BCL-XL with partial drug resistance to A-1331852 in mammalian cells.

Depositor

Abhishek Chakraborty

Article

Grubb et al Clin Cancer Res. 2022 Nov 1;28(21):4689-

Insert

BCL2L1 (BCL2L1 Human)

Use

Lentiviral

Tags

V5-tagged

Expression

Mammalian

Mutation

Changed Phenylalanine 97 to Tryptophan for partia…

Promoter

CMV

Available Since

Dec. 6, 2024

Availability

Academic Institutions and Nonprofits only

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pET28.His.3C.20D3Q.Tau2N4R

Plasmid

#226397

Purpose

Expresses his-tagged, 3C-cleavable 20D3Q mutant 2N4R tau for recombinant protein production in bacteria

Depositor

Bradley Hyman

Article

Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

Insert

Tau2N4R (MAPT Human, synthetic)

Tags

His.3C

Expression

Bacterial

Mutation

20D3Q, Tau2N4R

Available Since

Nov. 14, 2024

Availability

Academic Institutions and Nonprofits only

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pET28.His.3C.8D2Q.Tau2N4R

Plasmid

#226398

Purpose

Expresses his-tagged, 3C-cleavable 8D2Q mutant 2N4R tau for recombinant protein production in bacteria

Depositor

Bradley Hyman

Article

Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

Insert

Tau2N4R (MAPT Human, synthetic)

Tags

His.3C

Expression

Bacterial

Mutation

8D2Q.Tau2N4R

Available Since

Nov. 14, 2024

Availability

Academic Institutions and Nonprofits only

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SpyTag-RBD Omicron BQ.1.1

Plasmid

#214725

Purpose

Expresses SARS-CoV-2 Omicron BQ.1.1 RBD (receptor-binding domain from Spike) with N-terminal SpyTag fusion in mammalian cells

Depositor

Mark Howarth

Article

Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

Insert

Receptor-Binding Domain (S SARS-CoV-2)

Tags

SpyTag

Expression

Mammalian

Promoter

CMV

Available Since

June 17, 2024

Availability

Academic Institutions and Nonprofits only

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Quartet-SpyTag

Plasmid

#214726

Purpose

In mammalian cells expresses a Quartet of receptor-binding domains (RBDs) from the sarbecoviruses SHC014, Rs4081, RaTG13, and SARS-CoV-2 each separated by GS-linkers with a C-terminal SpyTag fusion

Depositor

Mark Howarth

Article

Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

Insert

Quartet-SpyTag (S Synthetic)

Tags

SpyTag

Expression

Mammalian

Promoter

CMV

Available Since

June 17, 2024

Availability

Academic Institutions and Nonprofits only

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