We narrowed to 18,339 results for: Mut

1. Tau BA 12->7 P301S

   Plasmid

   #203372

   Purpose

   For transfection and in vitro assay

   Depositor

   Stefan Stamm

   Article

   Margvelani et al Biochim Biophys Acta Mol Basis Dis. 2024

   Insert

   MAPT (MAPT Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   P301S

   Promoter

   CMVf

   Available Since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. Tau BA 12->7 G303V

   Plasmid

   #203373

   Purpose

   For transfection and in vitro assay

   Depositor

   Stefan Stamm

   Article

   Margvelani et al Biochim Biophys Acta Mol Basis Dis. 2024

   Insert

   MAPT (MAPT Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   G303V

   Promoter

   CMVf

   Available Since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pRRL-SFFV_V5-CHIC2-C6S_Tomato

   Plasmid

   #238128

   Purpose

   Expresses V5-tagged CHIC2 (with C6S mutation) with Tomato selectable marker.

   Depositor

   Arlene Sharpe

   Article

   LaFleur et al Nat Immunol. 2025 Sep;26(9):1476-1487. d

   Insert

   V5-tagged CHIC2 with C6S mutation
   

   Use

   Tags

   V5

   Expression

   Mammalian

   Mutation

   Changed cysteines from amino acids 102-109 to ser…

   Promoter

   SFFV

   Available Since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pSMPPv2-Tau-RING (M72E/I18R)

   Plasmid

   #233690

   Purpose

   Expression of Tau-RING I18R-M72E mutant in mammalian cells

   Depositor

   Leo James

   Article

   Miller et al Cell. 2024 Oct 17;187(21):5967-5980.e17.

   Insert

   Tau protein fused to TRIM21 RING domain carrying M72E/I18R mutations
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   April 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pHAGE2-TetO-Chim-Pchi-Q61A

   Plasmid

   #231520

   Purpose

   Expresses Pigoraptor chileana chimeric Sox mutant in mammalian cells, for lentivirus generation

   Depositor

   Ralf Jauch

   Article

   Gao et al Nat Commun. 2024 Nov 14;15(1):9868. doi:

   Insert

   Pchi HMG Q61A flanked with N- and C-termini of mSox2
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Point mutation at position 61 Q to A of the HMG d…

   Promoter

   Available Since

   March 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pHAGE2-TetO-Chim-Pchi-Q61A/E64M

   Plasmid

   #231521

   Purpose

   Expresses Pigoraptor chileana chimeric Sox mutant in mammalian cells, for lentivirus generation

   Depositor

   Ralf Jauch

   Article

   Gao et al Nat Commun. 2024 Nov 14;15(1):9868. doi:

   Insert

   Pchi HMG Q61A/E64M flanked with N- and C-termini of mSox2
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Point mutations at position 61 Q to A and 64 E to…

   Promoter

   Available Since

   March 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAG391

   Plasmid

   #226732

   Purpose

   Expresses a reporter for an alpha-helical OMM protein

   Depositor

   Jonathan Weissman

   Article

   Guna et al Science. 2022 Oct 21;378(6617):317-322.

   Insert

   MAVS (MAVS Human)
   

   Use

   Lentiviral

   Tags

   GFP11

   Expression

   Mutation

   Promoter

   Available Since

   Feb. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pPB9v2

   Plasmid

   #210029

   Purpose

   Contains cloning site for molecularly-tagged Cas9 gRNA constructs, inducible Cas9, rtTA-T2A-puro

   Depositor

   Michael Talkowski

   Article

   Nuttle et al Cell Rep Methods. 2023 Dec 5:100672. doi

   Inserts

   Cas9
   rtta-T2A-puro
   

   Use

   CRISPR

   Tags

   SV40 NLS and nucleoplasmin NLS

   Expression

   Mammalian

   Mutation

   Promoter

   EF-1α and TRE3G

   Available Since

   Feb. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pPB9P2

   Plasmid

   #210030

   Purpose

   Contains PE2 prime editing gRNA cloning site, inducible prime editor 2, rtTA-T2A-puro

   Depositor

   Michael Talkowski

   Article

   Nuttle et al Cell Rep Methods. 2023 Dec 5:100672. doi

   Inserts

   prime editor 2
   rtta-T2A-puro
   

   Use

   CRISPR

   Tags

   SV40 NLS

   Expression

   Mammalian

   Mutation

   Promoter

   EF-1α and TRE3G

   Available Since

   Feb. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pPB758

    Plasmid

    #210033

    Purpose

    Contains inducible Cas7-P2A-Cas5-T2A-Cas8, rtTA-T2A-puro

    Depositor

    Michael Talkowski

    Article

    Nuttle et al Cell Rep Methods. 2023 Dec 5:100672. doi

    Inserts

    Cas7-P2A-Cas5-T2A-Cas8
    rtta-T2A-puro
    

    Use

    CRISPR

    Tags

    SV40 NLS

    Expression

    Mammalian

    Mutation

    Promoter

    EF-1α and TRE3G

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pCS2+ 3xFLAG-FEM1B C186S

    Plasmid

    #230995

    Purpose

    Transient overexpression of mouse FEM1B in mammalian cells. Mutation abolishes substrate binding.

    Depositor

    Michael Rape

    Article

    Manford et al Cell. 2020 Oct 1;183(1):46-61.e21. doi:

    Insert

    FEM1B (Fem1b Mouse)
    

    Use

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    mutated Cys186 to Ser

    Promoter

    Available Since

    Jan. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCS2+ 3xFLAG-FEM1B L597A

    Plasmid

    #230994

    Purpose

    Transient overexpression of catalytic null mouse FEM1B in mammalian cells. Mutation abolishes interaction with CUL2.

    Depositor

    Michael Rape

    Article

    Manford et al Cell. 2020 Oct 1;183(1):46-61.e21. doi:

    Insert

    FEM1B (Fem1b Mouse)
    

    Use

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    mutated Leu597 to Ala

    Promoter

    Available Since

    Jan. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCas3-APOBEC1

    Plasmid

    #229536

    Purpose

    pMV_hyg encoding Cas3(wt)-rAPOBEC1 fusion construct and crRNA expression cassette. Respective crRNA spacer can be introduced via BsmBI restriction cloning

    Depositor

    Kevin Verstrepen

    Article

    Zimmermann et al Nat Commun. 2023 Jun 9;14(1):3389. doi:

    Inserts

    rAPOBEC1
    Cas3
    Uracil glycosylase inhibitor
    

    Use

    Tags

    XTEN

    Expression

    Bacterial and Yeast

    Mutation

    codon optimized for S.cerevisiae and codon optimi…

    Promoter

    Available Since

    Jan. 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pCas3-CDA1

    Plasmid

    #229534

    Purpose

    pMV_hyg encoding Cas3(wt)-CDA1 fusion construct and crRNA expression cassette. Respective crRNA spacer can be introduced via BsmBI restriction cloning

    Depositor

    Kevin Verstrepen

    Article

    Zimmermann et al Nat Commun. 2023 Jun 9;14(1):3389. doi:

    Inserts

    Cas3
    Cytidine deaminase
    Uracil glycosylase inhibitor
    

    Use

    Tags

    XTEN

    Expression

    Bacterial and Yeast

    Mutation

    codon optimized for S.cerevisiae and codon optimi…

    Promoter

    Available Since

    Jan. 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAG392

    Plasmid

    #226749

    Purpose

    CRISPRi guide RNA against ATP13A1

    Depositor

    Jonathan Weissman

    Article

    Guna et al Science. 2022 Oct 21;378(6617):317-322.

    Insert

    ATP13A1 (ATP13A1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Oct. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAG369

    Plasmid

    #226748

    Purpose

    CRISPRi guide RNA against EMC2

    Depositor

    Jonathan Weissman

    Article

    Guna et al Science. 2022 Oct 21;378(6617):317-322.

    Insert

    EMC2 (EMC2 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Oct. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pAG517

    Plasmid

    #226735

    Purpose

    Expresses a reporter for an alpha-helical OMM protein

    Depositor

    Jonathan Weissman

    Article

    Guna et al Science. 2022 Oct 21;378(6617):317-322.

    Insert

    BCL2L1 (BCL2L1 Human)
    

    Use

    Lentiviral

    Tags

    GFP11

    Expression

    Mutation

    Promoter

    Available Since

    Oct. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pICOZ-MAG-H181A

    Plasmid

    #218300

    Purpose

    Mammalian expression vector for expression of MAG transposase mutant

    Depositor

    Haoyi Wang

    Article

    Zhang et al Cell. 2024 Jul 11;187(14):3741-3760.e30.

    Insert

    H181A mutant of MAG transposase
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pICOZ-MAG-H181V

    Plasmid

    #218301

    Purpose

    Mammalian expression vector for expression of MAG transposase mutant

    Depositor

    Haoyi Wang

    Article

    Zhang et al Cell. 2024 Jul 11;187(14):3741-3760.e30.

    Insert

    H181V mutant of MAG transposase
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pICOZ-MAG-K241R

    Plasmid

    #218302

    Purpose

    Mammalian expression vector for expression of MAG transposase mutant

    Depositor

    Haoyi Wang

    Article

    Zhang et al Cell. 2024 Jul 11;187(14):3741-3760.e30.

    Insert

    K241R mutant of MAG transposase
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge