We narrowed to 24,922 results for: Spr

1. pLKO_HA.VSVg.C_NGFR

   Plasmid

   #158263

   Purpose

   Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

   Depositor

   Brian Brown

   Article

   Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

   Insert

   Pro-Code Tagged human dNGFR (NGFR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   HA.VSVg.C

   Mutation

   Truncation of the signaling domain

   Promoter

   EF1a

   Available Since

   Sept. 3, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pLKO_FLAG.VSVg.C_NGFR

   Plasmid

   #158260

   Purpose

   Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

   Depositor

   Brian Brown

   Article

   Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

   Insert

   Pro-Code Tagged human dNGFR (NGFR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   FLAG.VSVg.C

   Mutation

   Truncation of the signaling domain

   Promoter

   EF1a

   Available Since

   Sept. 3, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. DAPK1 gRNA (BRDN0001146680)

   Plasmid

   #76518

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human DAPK1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   DAPK1 (DAPK1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. GNE gRNA (BRDN0001149237)

   Plasmid

   #77833

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human GNE

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   GNE (GNE Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. BTK gRNA (BRDN0001146090)

   Plasmid

   #77073

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human BTK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   BTK (BTK Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. IKBKE gRNA (BRDN0001147958)

   Plasmid

   #77770

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human IKBKE

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   IKBKE (IKBKE Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. IKBKE gRNA (BRDN0001144791)

   Plasmid

   #77772

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human IKBKE

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   IKBKE (IKBKE Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. LYN gRNA (BRDN0001148376)

   Plasmid

   #77026

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human LYN

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   LYN (LYN Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. MAPK9 gRNA (BRDN0001147698)

   Plasmid

   #76718

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MAPK9

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MAPK9 (MAPK9 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. EXOSC10 gRNA (BRDN0001487044)

    Plasmid

    #77988

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human EXOSC10

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    EXOSC10 (EXOSC10 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. CHEK1 gRNA (BRDN0001145520)

    Plasmid

    #76643

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CHEK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CHEK1 (CHEK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. IRAK4 gRNA (BRDN0001146161)

    Plasmid

    #75664

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human IRAK4

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    IRAK4 (IRAK4 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. FGGY gRNA (BRDN0001145631)

    Plasmid

    #77109

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FGGY

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FGGY (FGGY Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. RPS6KB2 gRNA (BRDN0001146372)

    Plasmid

    #76057

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human RPS6KB2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    RPS6KB2 (RPS6KB2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. RPS6KB2 gRNA (BRDN0001146023)

    Plasmid

    #76058

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human RPS6KB2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    RPS6KB2 (RPS6KB2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. MLM3636-Prnp-CDS-Pos

    Plasmid

    #61857

    Purpose

    Expresses a gRNA plasmid targeting the prion gene's exon 3, positive strand

    Depositor

    Gerold Schmitt-Ulms

    Article

    Mehrabian et al PLoS One. 2014 Dec 9;9(12):e114594. doi:

    Insert

    PrP guiding sequence (Prnp Mouse)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    hU6 promoter

    Available Since

    Feb. 3, 2015

    Availability

    Academic Institutions and Nonprofits only

17. PEAK1 gRNA (BRDN0001147244)

    Plasmid

    #75854

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PEAK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PEAK1 (PEAK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. PEAK1 gRNA (BRDN0001147666)

    Plasmid

    #75855

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PEAK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PEAK1 (PEAK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. CHEK2 gRNA (BRDN0001146385)

    Plasmid

    #76488

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CHEK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CHEK2 (CHEK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. CHEK2 gRNA (BRDN0001145828)

    Plasmid

    #76489

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CHEK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CHEK2 (CHEK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge