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AiP12162 - pAAV-AiE0400h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2162)

Plasmid

#208151

Purpose

Direct-expressing SYFP2 in oligodendrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 23, 2023

Availability

Academic Institutions and Nonprofits only

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AiP12099 - pAAV-AiE0396m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2099)

Plasmid

#208149

Purpose

Direct-expressing SYFP2 in oligodendrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 23, 2023

Availability

Academic Institutions and Nonprofits only

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AiP12158 - pAAV-AiE0396h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2158)

Plasmid

#208148

Purpose

Direct-expressing SYFP2 in oligodendrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 20, 2023

Availability

Academic Institutions and Nonprofits only

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AiP12505 - pAAV-AiE0391h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2505)

Plasmid

#208145

Purpose

Direct-expressing SYFP2 in oligodendrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 20, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP1389 - pAAV-AiE2E160m-minBGpromoter-SYFP2-WPRE3-bGHpA

Plasmid

#208140

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1389 - pAAV-AiE2160m-minBG-SYFP2-WPRE-BGHpA

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

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AiP1457 - pAAV-AiE2E121m-minBGpromoter-SYFP2-WPRE3-bGHpA

Plasmid

#208138

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1457 - pAAV-AiE2121m-minBG-SYFP2-WPRE-BGHpA

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP1349 - pAAV-AiE2E120m-minBGpromoter-SYFP2-WPRE3-bGHpA

Plasmid

#208137

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1349 - pAAV-AiE2120m-minBG-SYFP2-WPRE-BGHpA

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP1346 - pAAV-AiE2E117m-minBGpromoter-SYFP2-WPRE3-bGHpA

Plasmid

#208135

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1346 - pAAV-AiE2117m-minBG-SYFP2-WPRE-BGHpA

Depositor

Allen Institute for Brain Science, Bosiljka Tasic

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12088 - pAAV-AiE0386m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2088)

Plasmid

#208132

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12122 - pAAV-AiE0385m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2122)

Plasmid

#208131

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

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AiP12098 - pAAV-AiE0374m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2098)

Plasmid

#208129

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12084 - pAAV-AiE0373m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2084)

Plasmid

#208128

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12495 - pAAV-AiE0385h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2495)

Plasmid

#208125

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12146 - pAAV-AiE0381h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2146)

Plasmid

#208124

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12144 - pAAV-AiE0376h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2144)

Plasmid

#208122

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12141 - pAAV-AiE0371h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2141)

Plasmid

#208121

Purpose

Direct-expressing SYFP2 in astrocytes AAV Virus

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12979 - pAAV-AiE0361h-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2979)

Plasmid

#208120

Purpose

AiE0361h is an enhancer sequence designed to drive AAV-mediated transgene expression in brain astrocytes

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AAV_pMBP-EGFP-caax (AAV8)

Viral Prep

#190155-AAV8

Purpose

Ready-to-use AAV8 particles produced from AAV_pMBP-EGFP-caax (#190155). In addition to the viral particles, you will also receive purified AAV_pMBP-EGFP-caax plasmid DNA. MBP-driven EGFP expression in oligodendrocytes. These AAV preparations are suitable purity for injection into animals.

Depositor

Brad Zuchero

Article

Lam et al Nat Commun. 2022 Sep 23;13(1):5583. doi:

Promoter

MBP

Available Since

Feb. 6, 2026

Availability

Academic Institutions and Nonprofits only
AAV_pMBP-EGFP-caax (AAV1)

Viral Prep

#190155-AAV1

Purpose

Ready-to-use AAV1 particles produced from AAV_pMBP-EGFP-caax (#190155). In addition to the viral particles, you will also receive purified AAV_pMBP-EGFP-caax plasmid DNA. MBP-driven EGFP expression in oligodendrocytes. These AAV preparations are suitable purity for injection into animals.

Depositor

Brad Zuchero

Article

Lam et al Nat Commun. 2022 Sep 23;13(1):5583. doi:

Promoter

MBP

Available Since

Jan. 15, 2026

Availability

Academic Institutions and Nonprofits only
pdCas9-DNMT3A-EGFP (ANV)

Plasmid

#71685

Purpose

Expression of mutant human codon-optimized dCas9-DNMT3A fusion (inactive catalytic domain of DNMT3A) with T2A-EGFP; cloning backbone for sgRNA

Depositor

Vlatka Zoldos

Article

Vojta et al Nucleic Acids Res. 2016 Mar 11. pii: gkw

Insert

S. pyogenes dCas9 fused with the inactivated (E756A) catalytic domain of human DNMT3A (amino acids P602-V912) and T2A-EGFP (DNMT3A Human, S. pyogenes, Synthetic)

Use

CRISPR

Tags

3xFLAG, SV40 NLS, and T2A-EGFP

Expression

Mammalian

Mutation

D10A and H840A in S.pyogenes Cas9; E756A inactiva…

Promoter

CBh

Available Since

March 7, 2016

Availability

Academic Institutions and Nonprofits only

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