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enz.043-SETD7-Y305F

Plasmid

#154045

Purpose

Expresses SETD7 (Y305F) in E. coli

Depositor

Christopher Voigt

Article

Wallace et al Advanced Functional Materials 2020

Insert

Histone-lysine N-methyltransferase SETD7 (SETD7 Human)

Tags

His, MBP

Expression

Bacterial

Mutation

changed tyrosine 305 to phenylalanine

Promoter

T7

Availability

Academic Institutions and Nonprofits only

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Pet28a His6-HSPB7 (zebrafish) C117S

Plasmid

#110072

Purpose

Express C117S mutant of Zebrafish His6-HSPB7 in bacteria

Depositor

Yimon Aye

Article

Surya et al ACS Chem Biol. 2018 Feb 8. doi: 10.1021/

Insert

His6-HSPB7 (hspb7 Zebrafish)

Tags

His6

Expression

Bacterial

Mutation

Cysteine 117 to Serine

Promoter

T7

Availability

Academic Institutions and Nonprofits only

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T7-5'UTR-PE7-3'UTR-polyA (CJT612)

Plasmid

#248222

Purpose

PE7 IVT vector for mRNA production

Depositor

Benjamin Kleinstiver

Article

Tou et al Nature. 2026 Mar 11. doi: 10.1038/s41586

Insert

5'UTR-PE7-3'UTR-polyA

Use

CRISPR; In vitro transcription

Tags

BPNLS

Expression

Mammalian

Mutation

nSpCas9(H840A); PE2 M-MLV(D200N/L603W/T330P/T306K…

Promoter

T7

Available Since

May 12, 2026

Availability

Academic Institutions and Nonprofits only

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pGenLenti murine CD300LF

Plasmid

#235668

Purpose

3rd Generation lentiviral vector for expression of murine CD300LF. Murine CD300LF is the receptor for murine norovirus, and expression confers susceptibility to this virus. Puromycin resistance.

Depositor

Edward Emmott

Article

Frazer J.T. et al bioRxiv 2026.03.19.712921; doi: 10.64898

Insert

Murine CD300LF (Cd300lf Mouse)

Use

Lentiviral

Promoter

CMV

Available Since

March 24, 2026

Availability

Industry, Academic Institutions, and Nonprofits

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pLVX-Flag-Polb(TM)-C-Hygro

Plasmid

#216778

Purpose

Flag-Polb(TM), C-terminal domain (AA 91-335) & a hygromycin resistance cassette; TM = L301R/V303R/V306R

Depositor

Robert Sobol

Article

Ibrahim et al NAR Cancer. 2025 Dec 31;7(4):zcaf057. do

Insert

Flag-Polb (POLB Human)

Use

Lentiviral

Tags

Flag

Expression

Mammalian

Mutation

C-terminal domain (amino acids 91-335); TM = L301…

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pENTR-Myc-TRIP12 SB

Plasmid

#216766

Purpose

Myc-TRIP12-SB; the substrate binding (SB) domain (AA 1-1650) of TRIP12 with an N-terminal Myc-tag

Depositor

Robert Sobol

Article

Ibrahim et al NAR Cancer. 2025 Dec 31;7(4):zcaf057. do

Insert

Myc-TRIP12-SB (TRIP12 Human)

Use

Cloning vector

Tags

Myc

Expression

Mammalian

Mutation

Substrate binding domain of TRIP12 (amino acids 1…

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLV-Puro-EF1A-XRCC1-Myc-3GS-TurboN

Plasmid

#248160

Purpose

XRCC1 with split TurboID: N

Depositor

Robert Sobol

Article

Ibrahim et al NAR Cancer. 2025 Dec 31;7(4):zcaf057. do

Insert

XRCC1 (XRCC1 Human)

Use

Lentiviral

Tags

Myc and Split TurboID: N

Expression

Mammalian

Available Since

Jan. 20, 2026

Availability

Academic Institutions and Nonprofits only

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huCof K95Q-mRFP

Plasmid

#245974

Purpose

Expression of cofilin with mutation in one actin binding domain

Depositor

James Bamburg

Article

Bernstein et al J Neurosci. 2012 May 9;32(19):6670-81. d

Insert

cofilin 1 (cfl1) (CFL1 Human)

Tags

mRFP

Expression

Mammalian

Mutation

K95Q

Promoter

CMV

Available Since

Oct. 21, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pX330_H3.2

Plasmid

#244239

Purpose

Expresses SpCas9 and a sgRNA targeting the human histone H3.2 loci for knock-in.

Depositor

Kazuhiro Maeshima

Article

Minami et al Sci Adv. 2025 Mar 28;11(13):eadu8400. do

Insert

sgRNA targeting human histone H3.2 (H3C14, H3C15 Human)

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Oct. 7, 2025

Availability

Academic Institutions and Nonprofits only

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EGFP_delta_EHMT1

Plasmid

#228816

Purpose

Expression of human EHMT1 with deletion of region between N-terminal 300 aa and C-terminal Ank+SET

Depositor

Shravanti Rampalli

Article

Biligiri et al PLoS Biol. 2024 Nov 7;22(11):e3002871. d

Insert

EHMT1 (EHMT1 Human)

Tags

EGFP

Expression

Mammalian

Mutation

deletion of region between N-terminal 300 aa and …

Available Since

Aug. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(+)_Nav1.6(WT, Y371C)-P2A-eGFP

Plasmid

#239768

Purpose

Expresses independantly TTX-resistant (Y371C) variant of mouse Nav1.6WT and eGFP in mammalian cells.

Depositor

Ivana Nikić-Spiegel

Article

Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060

Insert

Scn8a (Scn8a Mouse)

Expression

Mammalian

Mutation

Y371C

Promoter

CMV

Available Since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hCASP8_1k)-PGKpuro2ABFP-W

Plasmid

#208422

Purpose

Lentiviral gRNA plasmid targeting human CASP8 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

CASP8 (CASP8 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hCASP8_2b)-PGKpuro2ABFP-W

Plasmid

#208423

Purpose

Lentiviral gRNA plasmid targeting human CASP8 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

CASP8 (CASP8 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pGFP-mTet1-delCys pc3903

Plasmid

#201701

Purpose

Expresses of GFP-tagged mTet1-delCys in mammalian cells

Depositor

Cristina Cardoso

Article

Arroyo et al Nat Commun. 2022 Sep 2;13(1):5173. doi:

Insert

Tet1 (Tet1 Mouse)

Tags

GFP

Expression

Mammalian

Mutation

Deletion of the Cysteine rich domain of Tet1

Promoter

CAG

Available Since

June 25, 2025

Availability

Academic Institutions and Nonprofits only

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pGFP-mTet1s-delCys pc3904

Plasmid

#201702

Purpose

Expresses of GFP-tagged mTet1s-delCys in mammalian cells

Depositor

Cristina Cardoso

Article

Arroyo et al Nat Commun. 2022 Sep 2;13(1):5173. doi:

Insert

Tet1s (Tet1 Mouse)

Tags

GFP

Expression

Mammalian

Mutation

Deletion of the Cysteine rich domain of Tet1s

Promoter

CAG

Available Since

June 25, 2025

Availability

Academic Institutions and Nonprofits only

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IL2-AHDC2-Cherry in pmCherryN1

Plasmid

#187291

Purpose

Express pmCherry-IL2-AH-deltaC2

Depositor

Alpha Yap

Article

Budnar et al Dev Cell. 2019 Jun 17;49(6):894-906.e12.

Insert

Scraps interleukin-2 receptor alpha-subunit, anillin (IL2, ANLN Human)

Tags

mCherry

Expression

Mammalian

Mutation

AH-deltaC2

Promoter

CMV

Available Since

Feb. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.3_3xFLAG_SUMO_Eu1_HsAGO2(H56A, R68A, R97A, K98A)

Plasmid

#231379

Purpose

Express mutant human AGO2 with N-terminal 3xFLAG-SUMO_Eu1 tag in mammalian cells

Depositor

David Bartel

Article

Mohamed et al Cell Rep. 2025 Jan 28;44(1):115166. doi:

Insert

Human Argonaute2 (AGO2 Synthetic, Human)

Tags

3xFLAG-SUMO_Eu1

Expression

Mammalian

Mutation

H56A, R68A, R97A, K98A

Promoter

CMV

Available Since

Jan. 14, 2025

Availability

Academic Institutions and Nonprofits only

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pRRL-mouse STING #1-gRNA-Cas9-Puro

Plasmid

#186892

Purpose

gRNA targeting mouse STING (with Cas9 insert)

Depositor

Jonathan Kagan

Article

Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

Insert

Cas9 (Sting1 Mouse)

Use

Lentiviral

Available Since

Oct. 23, 2024

Availability

Academic Institutions and Nonprofits only

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pRRL-mouse STING #2-gRNA-Cas9-Puro

Plasmid

#186893

Purpose

gRNA targeting mouse STING (with Cas9 insert)

Depositor

Jonathan Kagan

Article

Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

Insert

Cas9 (Sting1 Mouse)

Use

Lentiviral

Available Since

Oct. 23, 2024

Availability

Academic Institutions and Nonprofits only

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pTRE3G-marmoset cGASdeltaN-HA

Plasmid

#186863

Purpose

Doxycycline-dependent expression of marmoset cGAS gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

Insert

Marmoset cGAS truncation mutant (160-547 a.a.) with C-terminal HA tag

Use

Retroviral

Tags

HA

Mutation

N-terminal truncation

Promoter

TRE3G

Available Since

Oct. 23, 2024

Availability

Academic Institutions and Nonprofits only

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