We narrowed to 1,274 results for: AP2

1. TFORF2116

   Plasmid

   #144385

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   NCOA6 (NCOA6 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   Aug. 14, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. pSLIK_hygro_BirA_CDKN1A

   Plasmid

   #136538

   Purpose

   Lentiviral expression vector for an inducible BirA-CDKN1A

   Depositor

   Kevin Janes

   Article

   Pereira et al Sci Signal. 2020 Apr 14;13(627). pii: 13

   Insert

   BirA-CDKN1A (CDKN1A )
   

   Use

   Lentiviral; Destinatioin vector for gateway cloni…

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. MBP-MEK1 S222TAG

   Plasmid

   #68302

   Purpose

   N-terminal MBP tagged human MEK1 gene S222TAG for bacterial expression

   Depositor

   Jesse Rinehart

   Article

   Pirman et al Nat Commun. 2015 Sep 9;6:8130. doi: 10.1

   Insert

   MBP-MEK1 S222TAG (MAP2K1 Synthetic, Human)
   

   Use

   Tags

   His and MBP

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   Sept. 10, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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4. MBP-MEK1 S218TAG

   Plasmid

   #68301

   Purpose

   N-terminal MBP tagged human MEK1 gene S218TAG for bacterial expression

   Depositor

   Jesse Rinehart

   Article

   Pirman et al Nat Commun. 2015 Sep 9;6:8130. doi: 10.1

   Insert

   MBP-MEK1 S218TAG (MAP2K1 Synthetic, Human)
   

   Use

   Tags

   His and MBP

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   Sept. 10, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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5. pEBG-MKK4-S255D/T259E (GST)

   Plasmid

   #21566

   Depositor

   Leonard Zon

   Article

   Sanchez et al Nature. . 372(6508):794-8.

   Insert

   mitogen-activated protein kinase kinase 4 (Map2k4 Mouse)
   

   Use

   Tags

   GST

   Expression

   Mammalian

   Mutation

   Serine 255 to Aspartic Acid, Threonine 259 to Gl…

   Promoter

   Available since

   July 17, 2009

   Availability

   Academic Institutions and Nonprofits only

6. FLAG-KLF12/pcDNA3.1-Neo

   Plasmid

   #81069

   Purpose

   Expression of epitope-tagged human KLF12 in mammalian cells.

   Depositor

   Julian Downward

   Article

   Godin-Heymann et al Oncogene. 2016 Jun 23;35(25):3324-34. do

   Insert

   FLAG-KLF12 (KLF12 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Sept. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. pEBG-MKK4-S255E/T259D (GST)

   Plasmid

   #21565

   Depositor

   Leonard Zon

   Article

   Sanchez et al Nature. . 372(6508):794-8.

   Insert

   mitogen-activated protein kinase kinase 4 (Map2k4 Mouse)
   

   Use

   Tags

   GST

   Expression

   Mammalian

   Mutation

   Serine 255 to Glutamic Acid, Threonine 259 to As…

   Promoter

   Available since

   July 22, 2009

   Availability

   Academic Institutions and Nonprofits only

8. TFORF2115

   Plasmid

   #144384

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   NCOA6 (NCOA6 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   Jan. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. MTOR gRNA (BRDN0001147813)

   Plasmid

   #76783

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MTOR

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MTOR (MTOR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. MTOR gRNA (BRDN0001145082)

    Plasmid

    #76782

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MTOR

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MTOR (MTOR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pGL-p21UTRm1&2

    Plasmid

    #20880

    Depositor

    Robert Blelloch

    Article

    Wang et al Nat Genet. 2008 Dec . 40(12):1478-83.

    Insert

    p21 3'UTR site 1 and 2 mutation (Cdkn1a Mouse)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    Predicted miRNA binding site 1 (Position ~420) GC…

    Promoter

    Available since

    Aug. 5, 2009

    Availability

    Academic Institutions and Nonprofits only

12. pLKO-Tet-On shYAP1-3

    Plasmid

    #193666

    Purpose

    Tet inducible knockdown of YAP1

    Depositor

    William Hahn

    Article

    Kim et al Dev Cell. 2022 Jan 24;57(2):212-227.e8.

    Insert

    YAP1 (YAP1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Dec. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. MTOR gRNA (BRDN0001145868)

    Plasmid

    #76784

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MTOR

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MTOR (MTOR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pcDNA3-HA p21 K161R, K163R

    Plasmid

    #78789

    Purpose

    To overexpress p21 K161R, K163R in Mammalian Cells

    Depositor

    Jaewhan Song

    Article

    Lee et al Cell Death Differ. 2013 Apr;20(4):620-9.

    Insert

    p21 (CDKN1A Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    K161R, K163R_muation

    Promoter

    CMV

    Available since

    June 8, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pCS3-MT-BX-6MYC p21

    Plasmid

    #78780

    Purpose

    To overexpress p21 in Mammalian Cells

    Depositor

    Jaewhan Song

    Article

    Lee et al Cell Death Differ. 2013 Apr;20(4):620-9.

    Insert

    p21 (CDKN1A Human)
    

    Use

    Tags

    6xMYC

    Expression

    Mammalian

    Mutation

    Promoter

    CMV IE94

    Available since

    June 8, 2016

    Availability

    Academic Institutions and Nonprofits only

16. pcDNA3-HA p21 K161Q, K163Q

    Plasmid

    #78790

    Purpose

    To overexpress p21 K161Q, K163Q in Mammalian Cells

    Depositor

    Jaewhan Song

    Article

    Lee et al Cell Death Differ. 2013 Apr;20(4):620-9.

    Insert

    p21 (CDKN1A Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    K161Q, K163Q_muation

    Promoter

    CMV

    Available since

    June 8, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. His 3C Kinase dead MKK6 1-334

    Plasmid

    #87882

    Purpose

    E. coli expression of MKK6 kinase dead

    Depositor

    Peter Mace

    Article

    Weijman et al Proc Natl Acad Sci U S A. 2017 Mar 14;11

    Insert

    MKK6 (MAP2K6 Human)
    

    Use

    Tags

    3C protease site and 6xHis

    Expression

    Bacterial

    Mutation

    K82A, kinase dead mutant

    Promoter

    T7

    Available since

    March 29, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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18. pHH0103_GRB2-2/2

    Plasmid

    #91410

    Purpose

    Protein expression and purification of human SH3 domain construct GRB2-2/2

    Depositor

    Sachdev Sidhu

    Article

    Teyra et al Structure. 2017 Oct 3;25(10):1598-1610.e

    Insert

    GRB2-2/2 (GRB2 Human)
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    March 19, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pEN_TTmiRc2_BirA_CDKN1A

    Plasmid

    #136523

    Purpose

    Used as a donor vector to clone into pSLIK

    Depositor

    Kevin Janes

    Article

    Pereira et al Sci Signal. 2020 Apr 14;13(627). pii: 13

    Insert

    CDKN1A (CDKN1A Human)
    

    Use

    Entry vector for gateway cloning

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 28, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pGEX Grb2-SH2 RK

    Plasmid

    #46441

    Depositor

    Bruce Mayer

    Article

    Machida et al Mol Cell. 2007 Jun 22;26(6):899-915.

    Insert

    Grb2 RK (GRB2 Human)
    

    Use

    Tags

    GST and PreScission

    Expression

    Bacterial

    Mutation

    contains amino acids 58-159

    Promoter

    Tac

    Available since

    July 10, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge