We narrowed to 18,031 results for: Mut

1. pUC19-HDRT-TRAC-CD19.CAR-Cas12a.PAM.mutated

   Plasmid

   #215769

   Purpose

   encodes for HDR template for optimized AsCas12a-mediated knock-in of a CD19-specific CAR into the TRAC locus

   Depositor

   Dimitrios Wagner

   Article

   Glaser et al Genome Biol. 2023 Apr 24;24(1):89. doi:

   Inserts

   TRAC-5' homology arm (TRAC Human)
   P2A-CD19.28.zeta-bgH (CD19 Mouse, Bovine, Human)
   TRAC-3' homology arm (TRAC Human)
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Cas12a PAM mutated

   Promoter

   Available Since

   June 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. EK0304 CMV-TO-BFPmut-stop-Bdnf.t1 (FLP-IN)

   Plasmid

   #191146

   Purpose

   Expression of only the trigger sequence for Bdnf.s1 (EK0301) in mammalian cells

   Depositor

   Xiaojing Gao

   Article

   Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

   Insert

   Bdnf.t1
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   WT

   Promoter

   CMV-TO

   Available Since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pDisplay-GRAB-HaloDAmut-IRES-EGFP-CAAX

   Plasmid

   #234411

   Purpose

   Expresses the chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut and a membrane-localized EGFP in mammalian cells

   Depositor

   Yulong Li

   Article

   Zheng et al Science. 2025 Jun 5;388: 6751. doi: http

   Insert

   GPCR activation based chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available Since

   June 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. EK0208 CMV-TO-BFPmut-stop-t70587 (FLP-IN)

   Plasmid

   #191138

   Purpose

   Expression of Trigger 1 in 3' UTR of an inactive BFP in mammalian cells

   Depositor

   Xiaojing Gao

   Article

   Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

   Insert

   t70587
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   WT

   Promoter

   CMV-TO

   Available Since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. Flag- MCL1-3A (S159, S162, T163 mutated to A)

   Plasmid

   #197458

   Purpose

   MCL-1 phosphodegron mutants

   Depositor

   Omar Khan

   Article

   Keyan et al Cancers (Basel). 2023 Jan 13;15(2):505.

   Insert

   MCL1 (MCL1 Human)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   S159A, S161A, T163A

   Promoter

   CMV

   Available Since

   Aug. 1, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLenti HRE mutant-Luc pGK Hygro

   Plasmid

   #118707

   Purpose

   reporter plasmid, HIF-responsive promoter (3xHRE) mutant- fused to firefly luciferase

   Depositor

   William Kaelin

   Article

   Briggs et al Cell. 2016 Jun 30;166(1):126-39. doi: 10

   Insert

   HREmutant-Luc
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   Nov. 26, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-hSyn-FLAG-HA-T6B-MUT-YFP

   Plasmid

   #235140

   Purpose

   Expresses the mutant T6B peptide fused with YFP under the human synapsin promoter

   Depositor

   Giordano Lippi

   Article

   Zolboot et al Neuron. 2025 Apr 1:S0896-6273(25)00181-3

   Insert

   mutant T6B peptide
   

   Use

   AAV

   Tags

   FLAG/HA

   Expression

   Mutation

   5 tryptophan residues of T6B-WT mutated

   Promoter

   hSyn

   Available Since

   April 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. DENV4 Rluc Reporter GND mutant Replicon

   Plasmid

   #118586

   Purpose

   For use as a positive control for translation of the Rluc gene in the transfected cells and negative control for replication.

   Depositor

   Radhakrishnan Padmanabhan

   Article

   Alcaraz-Estrada et al J Gen Virol. 2010 Nov;91(Pt 11):2713-8.

   Insert

   DENV4 Renilla luciferase gene (Rluc) reporter replicon containing replication-defective GND mutation in the NS5 polymerase gene.
   

   Use

   Yeast-e. col shuttle vector prs424

   Tags

   Expression

   Mutation

   The conserved GDD in the NS5 polymerase gene muta…

   Promoter

   Available Since

   Aug. 2, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCS2 stabilized mutant Beta Catenin-GFP

   Plasmid

   #29684

   Depositor

   Edward De Robertis

   Article

   Taelman et al Cell. 2010 Dec 23. 143(7):1136-48.

   Insert

   beta catenin (ctnnb1.L Frog)
   

   Use

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   S33A, S37A, T41A

   Promoter

   Available Since

   Oct. 5, 2011

   Availability

   Academic Institutions and Nonprofits only

10. pSB-CMV-MCS-Puro GEM-LTB4mut

    Plasmid

    #202642

    Purpose

    Expresses the LTB4-insensitive control sensor GEM-LTB4mut in mammalian cells

    Depositor

    Balázs Enyedi

    Article

    Tamas et al Nat Commun. 2023 Aug 1;14(1):4610. doi:

    Insert

    GEM-LTB4mut
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available Since

    Aug. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. EK0211 CMV-TO-BFPmut-stop-t17d9b (FLP-IN)

    Plasmid

    #191139

    Purpose

    Expression of Trigger 2 in 3' UTR of an inactive BFP in mammalian cells. Used as second input in OR, AND gates

    Depositor

    Xiaojing Gao

    Article

    Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

    Insert

    t17d9b
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    CMV-TO

    Available Since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. pRS305-LEU2-pHIS3-SV40NLS-PfV-GS-GFPMUT3

    Plasmid

    #203657

    Purpose

    Yeast integrative vector for the expression of the GFPMUT3-tagged nuclear localizing 40nm nucGEMs under the HIS3 promoter.

    Depositor

    Liam Holt

    Article

    Shu T et et al bioRxiv 2022

    Insert

    PfV
    

    Use

    Tags

    GFPMUT3

    Expression

    Yeast

    Mutation

    Promoter

    Available Since

    July 25, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLV-CMV-EGFP-PolB-PAMmut-Hygro

    Plasmid

    #176086

    Purpose

    EGFP fused to the N-terminus of a POLB containing a mutation in the PAM site used by POLBKOg1 & a hygromycin resistance cassette

    Depositor

    Robert Sobol

    Article

    Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

    Insert

    PolB (POLB Human)
    

    Use

    Lentiviral

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Mutation in the PAM site used by PolBKOg1

    Promoter

    CMV

    Available Since

    Jan. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcDNA3.1-TAT-1-101-FLAG basic mutant

    Plasmid

    #35985

    Depositor

    Susana Valente

    Article

    Mousseau et al Cell Host Microbe. 2012 Jul 19;12(1):97-

    Insert

    transactivating protein (tat )
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    tat from HIV1, 101 aa; R to A mutations at aa 56,…

    Promoter

    Available Since

    Sept. 6, 2012

    Availability

    Academic Institutions and Nonprofits only

    

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15. pcDNA3.1-CD40L (lose of function mutant)-mgSrtA

    Plasmid

    #125796

    Purpose

    for co-expression of a loss of function mutant of CD40L and mgSrtA on cell membrane. A negative control to plasmid pcDNA3.1-CD40L-mgSrtA.

    Depositor

    P. Chen

    Article

    Ge et al J Am Chem Soc. 2019 Feb 6;141(5):1833-18

    Insert

    CD40L (lose of function mutant)-mgSrtA
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    May 24, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. LLP340 pEF1a-NLS-scFvGCN4-DNMT3a (mutant)

    Plasmid

    #100944

    Purpose

    Single chain variable fragment antibody GCN4 fused to DNMT3a catalytic mutant, binds SunTag, with 3xTy1 tag

    Depositor

    Ryan Lister

    Article

    Pflueger et al Genome Res. 2018 Jun 15. pii: gr.233049.

    Insert

    scFvGCN4, sfGFP, GB1, DNMT3a catalytic mutant (DNMT3A Synthetic, Human)
    

    Use

    Tags

    3xTy1

    Expression

    Mammalian

    Mutation

    F636A, E660A, E725A, R295A

    Promoter

    Available Since

    June 21, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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17. pcDNA3puro-mGFP-FXR1a-Ccmut (N202P-V361P)

    Plasmid

    #225457

    Purpose

    Express mEGFP-fusion protein of FXR1 isoform a (N202P V361P)

    Depositor

    Christine Mayr

    Article

    Chen et al Cell. 5 August 2024. doi: 10.1016/j.cell

    Insert

    FXR1 isoform a (FXR1 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    N202P V361P

    Promoter

    CMV

    Available Since

    Oct. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pPICZ-pOst1-pro-alphaf(MUT1)-E2-Crimson

    Plasmid

    #117662

    Purpose

    Test intracellular localisation of E2-Crimson and study the secretion efficiency

    Depositor

    Pau Ferrer, Benjamin Glick

    Article

    Barrero et al Microb Cell Fact. 2018 Oct 12;17(1):161.

    Insert

    pOst1-pro-af(MUT1)-E2-Crimson
    

    Use

    Tags

    Expression

    Yeast

    Mutation

    This plasmid encodes the fluorescent protein E2-C…

    Promoter

    pAOX1

    Available Since

    Dec. 12, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCI-MS2V5-PABPC1 MLLEmut M161A/D165K

    Plasmid

    #65810

    Purpose

    expression of PABPC1-MS2 fusion, double mutant.

    Depositor

    Niels Gehring

    Article

    Fatscher et al RNA. 2014 Oct;20(10):1579-92. doi: 10.12

    Insert

    PABPC1 (PABPC4 Human)
    

    Use

    Tags

    MS2 stem loops and V5

    Expression

    Mammalian

    Mutation

    MLLEmut M161A/D165K

    Promoter

    CMV

    Available Since

    Sept. 17, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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20. pHR-SFFV-FLAG-TurboID-mutKIR-SQSTM1

    Plasmid

    #223719

    Purpose

    Expresses FLAG-TurboID-mutKIR-SQSTM1

    Depositor

    Benjamin Wolozin

    Article

    Ortiz et al bioRxiv [Preprint]. 2024 Jun 27:2023.12.

    Insert

    SQSTM1 (SQSTM1 Human)
    

    Use

    Lentiviral

    Tags

    TurboID

    Expression

    Mammalian

    Mutation

    Mutation 347-DPSTGE-352 to 347-APSAAA-352

    Promoter

    SFFV

    Available Since

    Aug. 28, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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