We narrowed to 18,398 results for: Mut

1. pUC19::ZmUBI-RWT4Ca_K217R/K327R

   Plasmid

   #237511

   Purpose

   Protoplast expression

   Depositor

   Gitta Coaker

   Article

   Sung et al Nat Genet. 2025 Apr 14. doi: 10.1038/s41

   Insert

   Rwt4Ca_K217R/K327R
   

   Use

   Tags

   Expression

   Plant

   Mutation

   Mutations at kinase active sites (K217R, K327R)

   Promoter

   Available Since

   July 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pIDTsmart-RC2-KO-delVP1-VP1-588TAG

   Plasmid

   #240123

   Purpose

   Express AAV2-KO (R585A,R588A) capsid with ncAA mutant at site 588 of VP1

   Depositor

   Abhishek Chatterjee

   Article

   Pham et al bioRxiv 2024.07.20.604406

   Inserts

   RC2-DelVP1-R585,588A
   VP1-588-TAG
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pTE5425

   Plasmid

   #229032

   Purpose

   Expression vector for 10xHis-phi29 DNA polymerase (catalytically inactive mutant D249E): PT7-lacO-g10leader-p2 dead-T7 terminator, CamR

   Depositor

   Tobias Erb

   Article

   Barthel et al bioRxiv 2025.07.08.663768; doi: 10.1101/

   Insert

   PT7-lacO-g10lead-10xHisTag-phi29 DNAP (D249E, catalytically inactive)
   

   Use

   Tags

   10x His-tag + Factor Xa recognition site

   Expression

   Bacterial

   Mutation

   Promoter

   PT7-lacO and T7 promoter

   Available Since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. fabp10a:DD-CreER; cryaa:mCerulean

   Plasmid

   #230076

   Purpose

   Expression of destabilized CreER in zebrafish hepatocytes.

   Depositor

   Sumeet Pal Singh

   Article

   Hovhannisyan et al bioRxiv 2025.05.23.655316

   Insert

   ltDHFR(DD)
   

   Use

   Zebrafish expression

   Tags

   CreER and HA

   Expression

   Mutation

   amino acids mutations: R12H, N23S, G67S, V78A, E1…

   Promoter

   fabp10a

   Available Since

   May 30, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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5. pYO290

   Plasmid

   #235731

   Purpose

   Protein expression in FL yeast VPS34 D731N mutant in yeast

   Depositor

   Roger Williams

   Article

   Rostislavleva et al Science. 2015 Oct 9;350(6257):aac7365. d

   Insert

   VPS34
   

   Use

   Tags

   Expression

   Yeast

   Mutation

   S2A, D731N

   Promoter

   Available Since

   May 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pB-T-PAF-Clu DD1 + TL1

   Plasmid

   #232019

   Purpose

   High expression of the Clusterin(A108E,L109S,E112K,P115Q,K304A,E307H, p.Arg214_Leu238del) mutant for purification.

   Depositor

   Franz-Ulrich Hartl

   Insert

   CLU (CLU Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   p.Ala108Glu, p.Leu109Ser, p.Glu112Lys, p.Pro115Gl…

   Promoter

   tetO

   Available Since

   May 13, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pB-T-PAF-Clu DD3

   Plasmid

   #215392

   Purpose

   High expression of the Clusterin(K123Q,R127Q,R130Q,R138Q,R282Q,R286Q,R289Q) mutant for purification.

   Depositor

   Franz-Ulrich Hartl

   Insert

   CLU (CLU Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   p.Lys123Gln, p. Arg127Gln, p.Arg130Gln, p.Arg138G…

   Promoter

   tetO

   Available Since

   May 13, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pB-T-PAF-Clu TL2

   Plasmid

   #215382

   Purpose

   High expression of the Clusterin(Y204S,Y206S,L207S,F209S,L211S,F218S,F219S,F220S) mutant for purification.

   Depositor

   Franz-Ulrich Hartl

   Insert

   CLU (CLU Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   p.Tyr204Ser, p.Tyr206Ser, p.Leu207Ser, p.Phe209Se…

   Promoter

   tetO

   Available Since

   May 13, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. 8522-E10

   Plasmid

   #234295

   Purpose

   Gateway ORF Entry clone of human SMAD2 with stop codon (for native or N-terminal fusions); S464A/S465A/S467A mutations (C-terminal phosphorylation sites dead)

   Depositor

   Dominic Esposito

   Insert

   SMAD2 S464A/S465A/S467A (SMAD2 Human)
   

   Use

   Gateway entry clone

   Tags

   Expression

   Mutation

   S464A/S465A/S467A; C-terminal phosphorylation sit…

   Promoter

   Available Since

   May 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pHRSV_CHARMS-V43D/E52K/R62E

    Plasmid

    #233940

    Purpose

    Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS three mutations in the death domain that disrupt oligomer formation

    Depositor

    Marcus Taylor

    Article

    Lichtenstein et al bioRxiv 2024.05.08.593169

    Insert

    CHARMS-V43D/E52K/R62E
    

    Use

    Lentiviral

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    SV40

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pHRSV_CHARMS-1xA

    Plasmid

    #233924

    Purpose

    Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-1xA which contains 1 TRAF6 binding motif with a alanine mutation

    Depositor

    Marcus Taylor

    Article

    Lichtenstein et al bioRxiv 2024.05.08.593169

    Insert

    CHARMS-1xA
    

    Use

    Lentiviral

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    SV40

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pHRSV_CHARMS-3xA

    Plasmid

    #233926

    Purpose

    Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-3xA which contains 3 TRAF6 binding motif with a alanine mutation

    Depositor

    Marcus Taylor

    Article

    Lichtenstein et al bioRxiv 2024.05.08.593169

    Insert

    CHARMS-3xA
    

    Use

    Lentiviral

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    SV40

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pHRSV_CHARMS-5xA

    Plasmid

    #233928

    Purpose

    Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-5xA which contains only 5 TRAF6 binding motifs with a alanine mutation

    Depositor

    Marcus Taylor

    Article

    Lichtenstein et al bioRxiv 2024.05.08.593169

    Insert

    CHARMS-5xA
    

    Use

    Lentiviral

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    SV40

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pHRSV_CHARMS-S34Y

    Plasmid

    #233929

    Purpose

    Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-S34Y which contains a mutation in the death domain that disrupt oligomer formation

    Depositor

    Marcus Taylor

    Article

    Lichtenstein et al bioRxiv 2024.05.08.593169

    Insert

    CHARMS-S34Y
    

    Use

    Lentiviral

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    SV40

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pHRSV_CHARMS-17xTA-3xAla

    Plasmid

    #233936

    Purpose

    Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-17xTA with alanine mutation in the TRAF6 binding motif

    Depositor

    Marcus Taylor

    Article

    Lichtenstein et al bioRxiv 2024.05.08.593169

    Insert

    CHARMS-17xTA-3xA
    

    Use

    Lentiviral

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    SV40

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pHRSV_CHARMS-20xTA-3xAla

    Plasmid

    #233937

    Purpose

    Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-20xTA with alanine mutation in the TRAF6 binding motif

    Depositor

    Marcus Taylor

    Article

    Lichtenstein et al bioRxiv 2024.05.08.593169

    Insert

    CHARMS-20xTA-20xA
    

    Use

    Lentiviral

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    SV40

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pYPQAT02

    Plasmid

    #223374

    Purpose

    T-DNA vector for SpCas9 mediated mutagenesis for plants; NGG PAM; Cas9 was driven by ZmUbi1 and the sgRNA was driven by AtU3 promoter; BASTA for plants selection.

    Depositor

    Yiping Qi

    Article

    Cheng et al Plant Cell. 2025 Apr 9:koaf081. doi: 10.

    Insert

    ZmUbi-SpCas9-AtU3-gRNA scaffold
    

    Use

    CRISPR

    Tags

    3x FLAG and NLS

    Expression

    Plant

    Mutation

    Promoter

    Available Since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pYPQAT04

    Plasmid

    #223376

    Purpose

    T-DNA vector for SpCas9 mediated mutagenesis for monocot plants; NGG PAM; Cas9 was driven by ZmUbi1 and the sgRNA was driven by OsU3 promoter; Hygromycin for plants selection.

    Depositor

    Yiping Qi

    Article

    Cheng et al Plant Cell. 2025 Apr 9:koaf081. doi: 10.

    Insert

    ZmUbi-SpCas9-OsU3-gRNA scaffold
    

    Use

    CRISPR

    Tags

    3x FLAG and NLS

    Expression

    Plant

    Mutation

    Promoter

    Available Since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pHR_CMV_MeltCasp1-37-GFP

    Plasmid

    #234069

    Purpose

    Encodes the caspase1 without CARD domain (with R391K mutation) controlled by a Melt variant with a switching temperature of 37°C

    Depositor

    Lukasz Bugaj

    Article

    Benman et al Nat Methods. 2025 Jan 23. doi: 10.1038/s

    Insert

    MeltCasp1-37-GFP
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Melt(C292A,Q355N); hcaspase1(R391K)

    Promoter

    CMV

    Available Since

    April 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. XZ135 CMV-TO-FKBP-ADARdd(QA) (FLP-IN)

    Plasmid

    #233376

    Purpose

    FKBP fused with ADAR2dd, with E488Q and T501A double mutation

    Depositor

    Xiaojing Gao

    Article

    Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

    Insert

    FKBP-ADAR2dd
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    E488Q, T501A on ADAR2dd

    Promoter

    CMV

    Available Since

    April 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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