We narrowed to 2,578 results for: EXO

1. pLenti-nSpCas9-BEACON2

   Plasmid

   #209041

   Purpose

   Lentiviral vector expressing doxycycline-inducible human codon-optimized cytosine base editor where BEACON2 is fused to the N-terminus of SpCas9(D10A)-sDNA Rad51-2xUGI-6xNLS

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Insert

   BEACON2-nSpCas9
   

   Use

   CRISPR and Lentiviral

   Tags

   FLAG-HA

   Expression

   Mammalian

   Mutation

   D10A

   Promoter

   Tight TRE promoter

   Available since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. RG6-BAP1_E7-D192D

   Plasmid

   #154024

   Purpose

   Bichromatic Fluorescent Splicing Reporter Minigene for Mutant BAP1 Exon 7 c.576C>T, p.D192D (Synonymous Mutation)

   Depositor

   Samuel Peña-Llopis

   Article

   Niersch et al iScience. 2021 Feb 12;24(3):102173. doi:

   Insert

   BAP1 Exon 7 Fused to DsRed1 and eGFP (BAP1 Human)
   

   Use

   Splicing reporter

   Tags

   DsRed1, FLAG, SV40 NLS, and eGFP

   Expression

   Mammalian

   Mutation

   BAP1 c.576C>T, p.D192D

   Promoter

   Available since

   Feb. 12, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. RG6-BAP1_E11-G312G

   Plasmid

   #154026

   Purpose

   Bichromatic Fluorescent Splicing Reporter Minigene for Mutant BAP1 Exon 11 c.936T>G, p.G312G (Synonymous Mutation)

   Depositor

   Samuel Peña-Llopis

   Article

   Niersch et al iScience. 2021 Feb 12;24(3):102173. doi:

   Insert

   BAP1 Exon 11 Fused to DsRed1 and eGFP (BAP1 Human)
   

   Use

   Splicing reporter

   Tags

   DsRed1, FLAG, SV40 NLS, and eGFP

   Expression

   Mammalian

   Mutation

   BAP1 c.936T>G, p.G312G

   Promoter

   Available since

   Feb. 12, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. pEH_AAV_TERT_prom_-124C>T_C7C_1.8kb

   Plasmid

   #183080

   Purpose

   rAAV transfer plasmid with ITRs flanking: (1) TERT -124C>T promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms, and (2) PGK-Puro.

   Depositor

   Aviv Regev

   Article

   Hodis et al Science. 2022 Apr 29;376(6592):eabi8175.

   Insert

   TERT -124C>T promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms (TERT Human)
   

   Use

   AAV; Homologous recombination donor template

   Tags

   Expression

   Mutation

   -124C>T promoter, Exon 1 C7C (C21>T21) sile…

   Promoter

   None for primary insert (Though partial TERT prom…

   Available since

   June 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pEH_AAV_TERT_prom_-146C>T_C7C_1.8kb

   Plasmid

   #183081

   Purpose

   rAAV transfer plasmid with ITRs flanking: (1) TERT -146C>T promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms, and (2) PGK-Puro.

   Depositor

   Aviv Regev

   Article

   Hodis et al Science. 2022 Apr 29;376(6592):eabi8175.

   Insert

   TERT -146C>T promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms (TERT Human)
   

   Use

   AAV; Homologous recombination donor template

   Tags

   Expression

   Mutation

   -146C>T promoter, Exon 1 C7C (C21>T21) sile…

   Promoter

   None for primary insert (Though partial TERT prom…

   Available since

   June 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pEH_AAV_TERT_prom_C7C_1.8kb

   Plasmid

   #183079

   Purpose

   rAAV transfer plasmid with ITRs flanking: (1) TERT wildtype promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms, and (2) PGK-Puro.

   Depositor

   Aviv Regev

   Article

   Hodis et al Science. 2022 Apr 29;376(6592):eabi8175.

   Insert

   TERT wildtype promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms (TERT Human)
   

   Use

   AAV; Homologous recombination donor template

   Tags

   Expression

   Mutation

   Wildtype promoter, Exon 1 C7C (C21>T21) silent…

   Promoter

   None for primary insert (Though partial TERT prom…

   Available since

   June 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. pMA2775

   Plasmid

   #46884

   Purpose

   Lentiviral vector encoding Tet-inducible mitochondrially targeted myc-tagged E.coli exonuclease III

   Depositor

   Mikhail Alexeyev

   Article

   Shokolenko et al DNA Repair (Amst). 2013 Jul;12(7):488-99

   Insert

   exonucleaseIII E. coli
   

   Use

   Lentiviral

   Tags

   Myc

   Expression

   Mammalian

   Mutation

   Promoter

   TRE-Tight

   Available since

   Aug. 14, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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8. FmnI GST369/pGEX6p1

   Plasmid

   #19322

   Depositor

   Philip Leder

   Article

   Zhou et al Exp Cell Res. 2006 Apr 15. 312(7):1119-2

   Insert

   ForminI Exon 9 (Fmn1 Mouse)
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   Sept. 15, 2008

   Availability

   Academic Institutions and Nonprofits only

9. VAMP2-pHmScarlet

   Plasmid

   #166890

   Purpose

   For vesicle exocytosis visualization using pHmScarlet

   Depositor

   Pingyong Xu

   Article

   Liu et al Nat Commun. 2021 Mar 3;12(1):1413. doi:

   Insert

   VAMP2 (Vamp2 Mouse)
   

   Use

   Tags

   pHmScarlet

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   April 8, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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10. VAMP2-pHmScarlet0

    Plasmid

    #166891

    Purpose

    For vesicle exocytosis visualization using pHmScarlet0

    Depositor

    Pingyong Xu

    Article

    Liu et al Nat Commun. 2021 Mar 3;12(1):1413. doi:

    Insert

    VAMP2 (Vamp2 Mouse)
    

    Use

    Tags

    pHmScarlet0

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    April 8, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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