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INSR gRNA (BRDN0001149243)

Plasmid

#75508

Purpose

3rd generation lentiviral gRNA plasmid targeting human INSR

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

INSR (INSR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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INSRR gRNA (BRDN0001487067)

Plasmid

#78062

Purpose

3rd generation lentiviral gRNA plasmid targeting human INSRR

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

INSRR (INSRR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 5, 2016

Availability

Academic Institutions and Nonprofits only

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ABL2 gRNA (BRDN0001146627)

Plasmid

#77178

Purpose

3rd generation lentiviral gRNA plasmid targeting human ABL2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ABL2 (ABL2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ABL2 gRNA (BRDN0001146737)

Plasmid

#77179

Purpose

3rd generation lentiviral gRNA plasmid targeting human ABL2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ABL2 (ABL2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HKDC1 gRNA (BRDN0001148616)

Plasmid

#76827

Purpose

3rd generation lentiviral gRNA plasmid targeting human HKDC1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HKDC1 (HKDC1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HKDC1 gRNA (BRDN0001146218)

Plasmid

#76828

Purpose

3rd generation lentiviral gRNA plasmid targeting human HKDC1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HKDC1 (HKDC1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HKDC1 gRNA (BRDN0001145441)

Plasmid

#76829

Purpose

3rd generation lentiviral gRNA plasmid targeting human HKDC1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HKDC1 (HKDC1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
HKDC1 gRNA (BRDN0001148023)

Plasmid

#76830

Purpose

3rd generation lentiviral gRNA plasmid targeting human HKDC1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HKDC1 (HKDC1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PIK3CA gRNA (BRDN0001146906)

Plasmid

#77417

Purpose

3rd generation lentiviral gRNA plasmid targeting human PIK3CA

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PIK3CA (PIK3CA Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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GRK5 gRNA (BRDN0001148840)

Plasmid

#76274

Purpose

3rd generation lentiviral gRNA plasmid targeting human GRK5

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

GRK5 (GRK5 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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BRDT gRNA (BRDN0001146712)

Plasmid

#77875

Purpose

3rd generation lentiviral gRNA plasmid targeting human BRDT

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

BRDT (BRDT Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 11, 2016

Availability

Academic Institutions and Nonprofits only

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FASTK gRNA (BRDN0001144738)

Plasmid

#77876

Purpose

3rd generation lentiviral gRNA plasmid targeting human FASTK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FASTK (FASTK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FASTK gRNA (BRDN0001145485)

Plasmid

#77877

Purpose

3rd generation lentiviral gRNA plasmid targeting human FASTK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FASTK (FASTK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FGFR4 gRNA (BRDN0001147333)

Plasmid

#77570

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR4 (FGFR4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FGFR4 gRNA (BRDN0001146151)

Plasmid

#77571

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR4 (FGFR4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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FGFR4 gRNA (BRDN0001148634)

Plasmid

#77572

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR4 (FGFR4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HUNK gRNA (BRDN0001148239)

Plasmid

#75940

Purpose

3rd generation lentiviral gRNA plasmid targeting human HUNK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HUNK (HUNK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pcDNA3-Flag-NSF/S647A

Plasmid

#74938

Purpose

Mammalian expression of human NSF mutant S647A (mutation in the D2 domain of the protein)

Depositor

Elisa Greggio

Article

Belluzzi et al Mol Neurodegener. 2016 Jan 13;11(1):1. d

Insert

NSF (NSF Human)

Tags

FLAG

Expression

Mammalian

Mutation

S647A (mutation in the D2 domain of the protein)

Promoter

CMV

Available Since

April 20, 2016

Availability

Academic Institutions and Nonprofits only
pCAG-RFP-mouse Tet1 (pc2329)

Plasmid

#246848

Purpose

Expresses mRFP tagged mouse Tet1 in mammalian cells. N-terminal tagged to mCherry.

Depositor

Cristina Cardoso

Article

Zhang et al Nucleic Acids Res. 2017 Apr 25. doi: 10.

Insert

Tet1 (Tet1 Mouse)

Tags

RFP

Expression

Mammalian

Promoter

CAG

Available Since

April 7, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG-mch-Tet2CD (pc3338)

Plasmid

#246862

Purpose

Expresses mCherry-tagged catalytic active domain of mouse Tet2 in mammalian cells. N-terminal tagged to mCherry.

Depositor

Cristina Cardoso

Article

Zhang et al Nucleic Acids Res. 2017 Apr 25. doi: 10.

Insert

Tet2 (Tet2 Mouse)

Tags

mCherry

Expression

Mammalian

Promoter

CAG

Available Since

April 7, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge