We narrowed to 1,321 results for: HRAS

1. pcDNA3.1-CHRFAM7ADelta2bp

   Plasmid

   #62515

   Purpose

   mammalian expression of human duplicated Alpha7 with 2 bp deletion (CHRFAM7A-∆2bp)

   Depositor

   Sherry Leonard, Henry Lester

   Article

   Wang et al J Biol Chem. 2014 Sep 19;289(38):26451-6

   Insert

   CHRFAM7ADelta2bp (CHRFAM7A Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   partially duplication of CHRNA7 with 2-bp deletio…

   Promoter

   CMV

   Available Since

   March 20, 2015

   Availability

   Industry, Academic Institutions, and Nonprofits

2. FLAG-MED30

   Plasmid

   #15426

   Depositor

   Joan Conaway, Ronald Conaway

   Article

   Sato et al J Biol Chem. 2003 Apr 25. 278(17):15123-

   Insert

   MED30 (Med30 Mouse)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   N/A

   Promoter

   Available Since

   Aug. 15, 2007

   Availability

   Academic Institutions and Nonprofits only

3. pcDNA3.1-CHRFAM7ADelta2bp-YFP

   Plasmid

   #62637

   Purpose

   mammalian expression of human duplicated Alpha7-2 bp deletion (CHRFAM7A-∆2bp) with YFP fused into M3-M4 loop

   Depositor

   Henry Lester

   Article

   Wang et al J Biol Chem. 2014 Sep 19;289(38):26451-6

   Insert

   CHRFAM7A (CHRFAM7A Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   there is a 2-bp deletion in exon 6 of CHRFAM7A an…

   Promoter

   CMV

   Available Since

   March 10, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCH1/RAD51o

   Plasmid

   #102562

   Purpose

   Express Human RAD51 protein codon optimzed for E.coli and the E.coli GorE Operon

   Depositor

   Maria Spies

   Article

   Subramanyam et al Proc Natl Acad Sci U S A. 2016 Oct 11;11

   Inserts

   Homo sapiens RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) (RAD51), transcript variant 1 (RAD51 Synthetic, Human)
   E. coli groE operon
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Codon optimized for E.coli Expression

   Promoter

   T7

   Available Since

   Feb. 7, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pEcNucC

   Plasmid

   #214050

   Purpose

   Bacterial expression plasmid for E. coli MS 115-1 NucC, a cA3-responsive nuclease known to cause abortive infection; used as a positive control in the Haliangium ochraceum type III CRISPR-Cas system

   Depositor

   Raymond Staals

   Article

   Steens et al Science. 2024 Feb 2;383(6682):512-519. d

   Insert

   EcNucC
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   WT

   Promoter

   lacUV5 promoter

   Available Since

   June 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCAG PSAM4-5HT3 HC IRES EGFP

   Plasmid

   #119740

   Purpose

   Chemogenetic activator expression plasmid

   Depositor

   Scott Sternson

   Article

   Magnus et al Science. 2019 Mar 14. pii: science.aav52

   Insert

   PSAM4 a75HT3 HC (homo) IRES eGFP (CHRNA7, HTR3A Synthetic, Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   L131G, Q139L, Y217F, R420Q, R424D, R428A

   Promoter

   CAG

   Available Since

   March 25, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pHAGE-RAD50

   Plasmid

   #116784

   Purpose

   Lentiviral expression of RAD50

   Depositor

   Kenneth Scott, Gordon Mills

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   RAD50 (RAD50 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   WT

   Promoter

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. 5'-3xFLAG Med24-exon minimal CMV pCDNA5

   Plasmid

   #212060

   Purpose

   LR vector for integration of Med24-exon into N2a FRT rtTA3 expression cells

   Depositor

   Benjamin Blencowe

   Article

   Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

   Insert

   Med24-exon (Med24 Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Jan. 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. 5'-3xFLAG Med24+exon minimal CMV pCDNA5

   Plasmid

   #212061

   Purpose

   LR vector for integration of Med24+exon(57nt) into N2a FRT rtTA3 expression cells

   Depositor

   Benjamin Blencowe

   Article

   Roth et al Mol Cell. 2023 Dec 7;83(23):4222-4238.e1

   Insert

   Med24+exon(57nt) (Med24 Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Jan. 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pD649-HAsp-TNFSF11-COMP5AP-AviTag-9xHis

    Plasmid

    #157264

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    TNFSF11 (TNFSF11 Human)
    

    Use

    Tags

    COMP5AP-AviTag-9xHis

    Expression

    Mammalian

    Mutation

    Promoter

    CMV/SP6

    Available Since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pORANGE GFP-CACNA1E KI

    Plasmid

    #131481

    Purpose

    Endogenous tagging of CaV2.3, R: N-terminal (amino acid position: G5)

    Depositor

    Harold MacGillavry

    Article

    Willems et al PLoS Biol. 2020 Apr 10;18(4):e3000665. d

    Insert

    gRNA and GFP donor (Cacna1e, Cacna1e Mouse, Rat)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6 and Cbh

    Available Since

    Sept. 25, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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12. CL20_mEGFP_MED13L_COL23A1

    Plasmid

    #205849

    Purpose

    Express mEGFP-tagged fusion protein, MED13L_COL23A1 from patient-derived sequence

    Depositor

    Richard Kriwacki

    Article

    Tripathi et al Nat Commun. 2023 Sep 28;14(1):6008. doi:

    Insert

    MED13L_COL23A1 (MED13L, COL23A1 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Nov. 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pD649-HAsp-TNFSF11-Fc(DAPA)-AviTag-6xHis

    Plasmid

    #156700

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    TNFSF11 (TNFSF11 Human)
    

    Use

    Tags

    Fc(DAPA)-AviTag-6xHis

    Expression

    Mammalian

    Mutation

    Fc region of human IgG contains D265A and P329A m…

    Promoter

    CMV/SP6

    Available Since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pBiT3.1-N_MED16:1-860

    Plasmid

    #211215

    Purpose

    Mammalian expression of full-length human MED16 isoform 3. N-terminal HiBiT tag.

    Depositor

    Cheryl Arrowsmith

    Article

    Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

    Insert

    MED16:M1-P860 (MED16 Human)
    

    Use

    Tags

    MVSGWRLFKKISGSSGGSSG

    Expression

    Mammalian

    Mutation

    isoform 3

    Promoter

    CMV

    Available Since

    March 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pBiT3.1-C_MED16:1-860

    Plasmid

    #211289

    Purpose

    Mammalian expression of full-length human MED16 isoform 3. C-terminal HiBiT tag.

    Depositor

    Cheryl Arrowsmith

    Article

    Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

    Insert

    MED16:M1-P860 (MED16 Human)
    

    Use

    Tags

    GSSGGSSGVSGWRLFKKIS

    Expression

    Mammalian

    Mutation

    wild type

    Promoter

    CMV

    Available Since

    Feb. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pUC19_18GZG

    Plasmid

    #117228

    Purpose

    shble flanked by an endogenous GAPDH promoter and terminator system

    Depositor

    Jackie Collier

    Article

    Faktorova et al Nat Methods. 2020 May;17(5):481-494. doi

    Insert

    shble
    

    Use

    Thraustochytrid expression

    Tags

    Expression

    Mutation

    Promoter

    GAPDH

    Available Since

    Oct. 11, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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17. RAS mutant clone collection

    Plasmid Kit

    #1000000089

    Purpose

    Wild-type and mutant HRAS, NRAS, KRAS4a and KRAS4b gene plasmids as Gateway entry clones

    Depositor

    Dominic Esposito

    Available Since

    Dec. 1, 2016

    Availability

    Academic Institutions and Nonprofits only

18. Target Accelerator Pan-Cancer Mutant Collection

    Plasmid Kit

    #1000000103

    Purpose

    Panel of cancer alleles that have undergone basic, functional screening; full-length, human clones (454 mutant and 177 corresponding wild-type) in the Gateway cloning system

    Depositor

    Jesse Boehm

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

19. RAS Pathway 2.0 Clone Collection

    Plasmid Kit

    #1000000070

    Purpose

    Collection contains 180 genes in the “RAS pathway version 2.0”, a crowdsourced pathway map of the RAS signaling pathway; For use with Gateway cloning or FNLCR Combinatorial Cloning Platform

    Depositor

    Dominic Esposito

    Available Since

    March 1, 2016

    Availability

    Academic Institutions and Nonprofits only

20. Target Accelerator Genetic Pathway Reference Set

    Plasmid Kit

    #1000000105

    Purpose

    Collection of genes and mutations for reference pathway signatures and phenotypes to compare with those derived from cancer alleles; represent over 25 cellular signaling pathways and processes

    Depositor

    Jesse Boehm

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only