We narrowed to 8,785 results for: sgrna

1. LentiCRISPR-B_sgRNA_EXOSC2 (pP18(T)_C3-AVA4067)

   Plasmid

   #239301

   Purpose

   Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC2

   Depositor

   Andrei Alexandrov

   Article

   Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

   Insert

   U6-driven sgRNA targeting EXOSC2 (EXOSC2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   Aug. 4, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. LentiCRISPR-B_sgRNA_EXOSC4 (pP18(T)_C11-AVA4065)

   Plasmid

   #239302

   Purpose

   Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC4

   Depositor

   Andrei Alexandrov

   Article

   Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

   Insert

   U6-driven sgRNA targeting EXOSC4 (EXOSC4 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   Aug. 4, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. LentiCRISPR-B_sgRNA_EXOSC5 (pP18(T)_B12-AVA4068)

   Plasmid

   #239303

   Purpose

   Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC5

   Depositor

   Andrei Alexandrov

   Article

   Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

   Insert

   U6-driven sgRNA targeting EXOSC5 (EXOSC5 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   Aug. 4, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. sgPlxnb2-2 in pT4-U6-sgRNA-CMV-EGFP

   Plasmid

   #239589

   Purpose

   expresses guide#2 to boost the expression of mouse Plxnb2, via CRISPRa

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   sgRNA targeting TSS-upstream reagion of Plxnb2 (Plxnb2 Mouse)
   

   Use

   Sleeping beauty (sb) transposon

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   June 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. sgPlxnb2-3 in pT4-U6-sgRNA-CMV-EGFP

   Plasmid

   #239590

   Purpose

   expresses guide#3 to boost the expression of mouse Plxnb2, via CRISPRa

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   sgRNA targeting TSS-upstream reagion of Plxnb2 (Plxnb2 Mouse)
   

   Use

   Sleeping beauty (sb) transposon

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   June 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. sgPlxnb2-1 in pT4-U6-sgRNA-CMV-EGFP

   Plasmid

   #239588

   Purpose

   expresses guide#1 to boost the expression of mouse Plxnb2, via CRISPRa

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   sgRNA targeting TSS-upstream reagion of Plxnb2 (Plxnb2 Mouse)
   

   Use

   Sleeping beauty (sb) transposon

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   June 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. Donor-attp-u6-blank-sgrna-backbone

   Plasmid

   #234076

   Purpose

   Blank donor for Perturb Seq landing pad with Pa01 recombinase at the AAVS1 loci

   Depositor

   Gary Hon

   Article

   Sivakumar et al bioRxiv [Preprint]. 2025 Jan 23:2025.01.

   Insert

   sgRNA-Blank
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   May 20, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLV-hUbC-EGFP-sgRNA.FOXA1/A2/A3_CRISPRi

   Plasmid

   #216166

   Purpose

   Express the gRNAs for the human FOXA1/A2/A3-CRISPRi

   Depositor

   Makiko Iwafuchi

   Article

   Matsui et al Mol Cell. 2024 Jan 4:S1097-2765(23)01026

   Insert

   sgRNA-FOXA1-Rank1, sgRNA-FOXA2-Rank2, sgRNA-FOXA2-Rank1, and sgRNA-FOXA3-Rank1 (FOXA1, FOXA2, FOXA3 Human)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mutation

   Promoter

   phU6, ph7SK, phH1, pmU6

   Available Since

   Feb. 21, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pX330-MM002-ZFP143-C-terminal-sgRNA

   Plasmid

   #212706

   Purpose

   Plasmid for transient expression of pspCas9(BB)-2A-Puro nuclease and sgRNA targetting the C terminal of Zfp143 locus

   Depositor

   Elzo de Wit

   Insert

   ZFP143 C-terminal sgRNA (Zfp143 Mouse)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   Dec. 17, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pX330-U6-(sgRNA-T2)-Chimeric_BB-CBh-hSpCas9

    Plasmid

    #223323

    Purpose

    Human codon optimized Cas9 expressing plasmid that carries the sgRNA T2 from Mali et al., 2013 (10.1126/science.1232033).

    Depositor

    Jonathan Arias

    Article

    Petruskeviciute et al Stem Cell Res. 2024 Dec 12;82:103628. do

    Insert

    SpCas9 and sgRNA-T2 (cas9 )
    

    Use

    CRISPR and Synthetic Biology

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available Since

    Dec. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pC130: pAAV.CMV-CasRx-VEGFA sgRNA

    Plasmid

    #203443

    Purpose

    Plasmid expressing active RfxCas13d with VEGFA mRNA targeting gRNA

    Depositor

    Guei-Sheung Liu

    Article

    Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

    Inserts

    U6-VEGFA sgRNA
    RfxCas13d
    

    Use

    AAV

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV and U6

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pM149: pAAV.CMV-Cas13e-VEGFA sgRNA

    Plasmid

    #203447

    Purpose

    Plasmid expressing active Cas13e with VEGFA mRNA targeting gRNA

    Depositor

    Guei-Sheung Liu

    Article

    Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

    Inserts

    U6-VEGFA sgRNA
    Cas13e
    

    Use

    AAV

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV and U6

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pM155: pAAV.CMV-Cas13e (GenScript CO)-NT sgRNA

    Plasmid

    #203451

    Purpose

    Plasmid expressing active and codon optimised Cas13e with non-targeting gRNA

    Depositor

    Guei-Sheung Liu

    Article

    Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

    Inserts

    U6-non targeting (NT) sgRNA
    Cas13e
    

    Use

    AAV

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Codon optimised using GenScript tool

    Promoter

    CMV and U6

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pC368: pAAV.CMV-Cas13e-VEGFA sgRNA2

    Plasmid

    #227800

    Purpose

    Plasmid expressing active Cas13e with VEGFA mRNA targeting gRNA2

    Depositor

    Guei-Sheung Liu

    Article

    Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

    Inserts

    U6-VEGFA sgRNA 2 (Vegfa Synthetic)
    Cas13e
    

    Use

    AAV

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pC369: pAAV.CMV-Cas13e-VEGFA sgRNA3

    Plasmid

    #227801

    Purpose

    Plasmid expressing active Cas13e with VEGFA mRNA targeting gRNA3

    Depositor

    Guei-Sheung Liu

    Article

    Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

    Inserts

    U6-VEGFA sgRNA 3 (Vegfa Synthetic)
    Cas13e
    

    Use

    AAV

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pAAV-Tnnt2-Cre-U6-Lmna-sgRNA

    Plasmid

    #206178

    Purpose

    Expresses Cre recombinase specifically in cardiomyocytes and uses U6 promoter to express sgRNAs targeting murine Lmna exon 10

    Depositor

    Yuxuan Guo

    Article

    Sun et al JACC Basic Transl Sci. 2024 Aug 21;9(11)

    Insert

    Cre
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    cTnT

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. Tol2-U6.3-sgRNA-empty-GFP

    Plasmid

    #221843

    Purpose

    empty vector to clone custom sgRNA into BsaI sites to express sgRNA from chick U6.3 promoter expresses GFP reporter from GAGC promoter

    Depositor

    Stephen Terry

    Article

    O’Sullivan et al bioRxiv 2024.03.04.583298

    Insert

    EGFP
    

    Use

    CRISPR; Tol2 transposon optimised for chick expre…

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CAGC

    Available Since

    July 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Tol2-U6.3-sgRNA-DNM1L -GFP

    Plasmid

    #221845

    Purpose

    Tol2 transposon expressing sgRNA targeting chick DNM1L from chick U6.3 promoter expresses GFP reporter from GAGC promoter

    Depositor

    Stephen Terry

    Article

    O’Sullivan et al bioRxiv 2024.03.04.583298

    Inserts

    EGFP
    DNM1L sgRNA-gTGTTTTCCGACCATCCTCTG
    

    Use

    CRISPR; Tol2 transposon optimised for chick expre…

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CAGC and U6.3 chick

    Available Since

    July 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. Tol2-U6.3-sgRNA-MFN1-GFP

    Plasmid

    #221846

    Purpose

    Tol2 transposon expressing sgRNA targeting chick MFN1 from chick U6.3 promoter expresses GFP reporter from GAGC promote

    Depositor

    Stephen Terry

    Article

    O’Sullivan et al bioRxiv 2024.03.04.583298

    Inserts

    EGFP
    MFN1 sgRNA-GAGAAGAAGAGCGTCAAGGT
    

    Use

    CRISPR; Tol2 transposon optimised for chick expre…

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CAGC and U6.3 chick

    Available Since

    July 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pCAG-eSpCas9-2A-GFP-sgRNA-Lig4

    Plasmid

    #220494

    Purpose

    To generate LIG4 KO in human cells. Co-expresses eSpCas9(1.1), GFP and a guide RNA against LIG4 exon 3.

    Depositor

    Sébastien Britton

    Article

    Bossaert et al bioRxiv [Preprint]. 2024 Jan 4:2024.01.0

    Insert

    sgRNA targeting LIG4 exon 3 (LIG4 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available Since

    July 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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