We narrowed to 6,134 results for: nls

1. TOPO-CHR12:132.68MB LG4

   Plasmid

   #226454

   Purpose

   Encodes an LG4 enhancer for subcloning or for assays using M13 phage

   Depositor

   Glen Borchert

   Article

   DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

   Insert

   CHR12:132.68MB LG4
   

   Use

   Cloning vector

   Tags

   Expression

   Mutation

   No

   Promoter

   Available since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. TOPO-LG4_chr5:550kb antisense

   Plasmid

   #205468

   Purpose

   Enhancer containing plasmid used for assessing enhancer::promoter interactions

   Depositor

   Glen Borchert

   Article

   DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

   Insert

   chr5:550kb LG4
   

   Use

   Synthetic Biology; Subcloning of taq-amplified pc…

   Tags

   Expression

   Mutation

   Promoter

   Available since

   July 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. FUS LC 4QQ->AA

   Plasmid

   #226600

   Purpose

   4 glutamine pairs to alanine pairs at positions 27, 28, 92, 93, 132, 133, 157, 158

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC 4QQ->AA (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   4 QQ pairs replaced with AA pairs at positions 27…

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. FUS LC 4QQ->GG

   Plasmid

   #226601

   Purpose

   4 glutamine pairs to glycine pairs at positions 27, 28, 92, 93, 132, 133, 157, 158

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC 4QQ->GG (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   4 QQ pairs replaced with GG pairs at positions 27…

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. FUS LC 4QQ->NN

   Plasmid

   #226602

   Purpose

   4 glutamine pairs to asparagine pairs at positions 27, 28, 92, 93, 132, 133, 157, 158

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC 4QQ->NN (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   4 glutamine pairs to asparagine pairs at position…

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. TDP-43 _CTD_5A→M_IDR + 5M→A_CR

   Plasmid

   #194268

   Purpose

   Expresses 6xHis-tagged C-terminal domain of TDP-43 with TDP-43 _CTD_5A→M_IDR + 5M→A_CR

   Depositor

   Nicolas Fawzi

   Article

   Mohanty et al Proc Natl Acad Sci U S A. 2023 Aug 22;12

   Insert

   TDP-43 (TARDBP Human, Synthetic)
   

   Use

   Tags

   6XHistag

   Expression

   Bacterial

   Mutation

   A297M, A367M, A381M, A388M, A391M M322A, M323A, M…

   Promoter

   T7

   Available since

   Oct. 26, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pGMC00003

   Plasmid

   #166720

   Purpose

   sgRNA against mouse Kitl

   Depositor

   Raj Chari

   Article

   Rice et al Nat Commun. 2018 Nov 30;9(1):5099. doi:

   Insert

   Kitl (Kitl Mouse)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 9, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pGMC00004

   Plasmid

   #166721

   Purpose

   sgRNA against mouse Kitl

   Depositor

   Raj Chari

   Article

   Rice et al Nat Commun. 2018 Nov 30;9(1):5099. doi:

   Insert

   Kitl (Kitl Mouse)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 9, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pLV-PGK-dt/CBA-EGFP-R106bT

   Plasmid

   #163921

   Purpose

   Serves as control to pLV-PGK-dt/CBA-EGFP-106bT.

   Depositor

   John Engelhardt

   Article

   Choi et al Genes (Basel). 2020 Oct 6;11(10). pii: g

   Insert

   dtomato and EGFP
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Added 4-tandem reverse orientation-mir-106b-targe…

   Promoter

   Available since

   Feb. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. MBP-hnRNPA2_LC_R191K_R201K_R216K_R254K

    Plasmid

    #104467

    Purpose

    express MBP hnRNPA2 LC with 4 R to K mutations

    Depositor

    Nicolas Fawzi

    Article

    Ryan et al Mol Cell. 2018 Jan 17. pii: S1097-2765(1

    Insert

    hnRNPA2 (HNRNPA2B1 Human)
    

    Use

    Tags

    His-MBP

    Expression

    Bacterial

    Mutation

    R191K R201K R216K R254K

    Promoter

    Available since

    Jan. 18, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. SGEP-sh-Hs-PHGDH-1956

    Plasmid

    #188670

    Purpose

    shRNA

    Depositor

    Lewis Cantley

    Insert

    shPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. SGEP-sh-Hs-PHGDH-1883

    Plasmid

    #188669

    Purpose

    shRNA

    Depositor

    Lewis Cantley

    Insert

    shPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. TC9pAB

    Plasmid

    #71310

    Purpose

    used as a template for in vitro transcription of Cas9 mRNA after linearizing with BbsI

    Depositor

    Karl Degenhardt

    Insert

    Cas9
    

    Use

    In vitro transcription

    Tags

    NLS

    Expression

    Mutation

    Promoter

    T7

    Available since

    Dec. 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. PX385 Streptococcus pasteurianus Cas9

    Plasmid

    #68322

    Purpose

    Streptococcus pasteurianus Cas9

    Depositor

    Feng Zhang

    Insert

    SpaCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 25, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. PX381 Filifactor alocis Cas9

    Plasmid

    #68318

    Purpose

    Filifactor alocis Cas9

    Depositor

    Feng Zhang

    Insert

    FaCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 25, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. PX396 Parvibaculum lavamentivorans Cas9

    Plasmid

    #68333

    Purpose

    Parvibaculum lavamentivorans Cas9

    Depositor

    Feng Zhang

    Insert

    PlCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 24, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. PX377 Corynebacter diphtheriae Cas9

    Plasmid

    #68314

    Purpose

    Corynebacter diphtheriae Cas9

    Depositor

    Feng Zhang

    Insert

    CdCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Sept. 28, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. PX405 Neisseria meningitidis Cas9

    Plasmid

    #68702

    Purpose

    Neisseria meningitidis Cas9

    Depositor

    Feng Zhang

    Insert

    NmCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 25, 2015

    Availability

    Academic Institutions and Nonprofits only

19. PX394 Neisseria cinerea Cas9

    Plasmid

    #68331

    Purpose

    Neisseria cinerea Cas9

    Depositor

    Feng Zhang

    Insert

    NcCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 20, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. ipUSEPR-sg-Hs-PHGDH-1

    Plasmid

    #188675

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. PX406 Pasteurella multocida Cas9

    Plasmid

    #68703

    Purpose

    Pasteurella multocida Cas9

    Depositor

    Feng Zhang

    Insert

    PmCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 25, 2015

    Availability

    Academic Institutions and Nonprofits only

22. PX390 Flavobacterium columnare Cas9

    Plasmid

    #68327

    Purpose

    Flavobacterium columnare Cas9

    Depositor

    Feng Zhang

    Insert

    FcCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 24, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. PX383 Lactobacillus johnsonii Cas9

    Plasmid

    #68320

    Purpose

    Lactobacillus johnsonii Cas9

    Depositor

    Feng Zhang

    Insert

    LjCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Sept. 28, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. PX382 Staphylococcus pseudintermedius Cas9

    Plasmid

    #68319

    Purpose

    Staphylococcus pseudintermedius Cas9

    Depositor

    Feng Zhang

    Insert

    SpsCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 25, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. PX386 Lactobacillus farciminis Cas9

    Plasmid

    #68323

    Purpose

    Lactobacillus farciminis Cas9

    Depositor

    Feng Zhang

    Insert

    LfCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 26, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. PX395 Roseburia intestinalis Cas9

    Plasmid

    #68332

    Purpose

    Roseburia intestinalis Cas9

    Depositor

    Feng Zhang

    Insert

    RiCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 24, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. PX393 Gluconacetobacter diazotrophicus Cas9

    Plasmid

    #68330

    Purpose

    Gluconacetobacter diazotrophicus Cas9

    Depositor

    Feng Zhang

    Insert

    GdCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 20, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. AmCyan-P2A-Xerry

    Plasmid

    #48686

    Purpose

    Expresses AmCyan while the mCherry gene has been mutated

    Depositor

    Ilpo Huhtaniemi

    Insert

    AmCyan
    

    Use

    Tags

    mutant mCherry (truncated)

    Expression

    Mammalian

    Mutation

    SV40 NLS

    Promoter

    CMV

    Available since

    Nov. 6, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. PX389 Fluviicola taffensis Cas9

    Plasmid

    #68326

    Purpose

    Fluviicola taffensis Cas9

    Depositor

    Feng Zhang

    Insert

    FtCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Sept. 30, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. PX388 Bacteroides coprophilus Cas9

    Plasmid

    #68325

    Purpose

    Bacteroides coprophilus Cas9

    Depositor

    Feng Zhang

    Insert

    BcCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Sept. 30, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. PX378 Sutterella wadsworthensis Cas9

    Plasmid

    #68315

    Purpose

    Sutterella wadsworthensis Cas9

    Depositor

    Feng Zhang

    Insert

    SwCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 25, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. PX387 Mycoplasma mobile Cas9

    Plasmid

    #68324

    Purpose

    Mycoplasma mobile Cas9

    Depositor

    Feng Zhang

    Insert

    MmCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 25, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. PX392 Azospirillum B510 Cas9

    Plasmid

    #68329

    Purpose

    Azospirillum B510 Cas9

    Depositor

    Feng Zhang

    Insert

    AzoCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 24, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. SGEP-sh-Hs-PHGDH-67

    Plasmid

    #188671

    Purpose

    shRNA

    Depositor

    Lewis Cantley

    Insert

    shPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. SGEP-sh-Hs-PHGDH-1968

    Plasmid

    #188673

    Purpose

    shRNA

    Depositor

    Lewis Cantley

    Insert

    shPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. SGEP-sh-Hs-PHGDH-1957

    Plasmid

    #188674

    Purpose

    shRNA

    Depositor

    Lewis Cantley

    Insert

    shPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. ipUSEPR-sg-Hs-PHGDH-2

    Plasmid

    #188676

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. SGEP-sh-Hs-PHGDH-1967

    Plasmid

    #188672

    Purpose

    shRNA

    Depositor

    Lewis Cantley

    Insert

    shPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. ipUSEPR-sg-Hs-PHGDH-5

    Plasmid

    #188679

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. ipUSEPR-sg-Hs-PHGDH-6

    Plasmid

    #188680

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

41. ipUSEPR-sg-Hs-PHGDH-4

    Plasmid

    #188678

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

42. ipUSEPR-sg-Hs-PHGDH-3

    Plasmid

    #188677

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgPHGDH (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

43. GeneWeld Vectors for Targeted Integration Using CRISPR/Cas9

    Plasmid Kit

    #1000000154

    Purpose

    Vectors for integration using short homology and CRISPR/Cas9 to produce knockout alleles with and without a fluorescent reporter, fusion proteins with endogenous genes, and Cre drivers.

    Depositor

    Jeffrey Essner

    Available since

    Aug. 6, 2019

    Availability

    Academic Institutions and Nonprofits only

44. pCMV-ABE8eWQ

    Plasmid

    #161815

    Purpose

    Expresses ABE8eWQ in mammalian cells

    Depositor

    Sangsu Bae

    Insert

    bpNLS-TadA8e(V106W/D108Q)-32AA linker-hSpCas9(D10A)-bpNLS-P2A-EGFP-NLS
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    D10A in S. pyogenes Cas9, TadA mutations describe…

    Promoter

    Available since

    Jan. 4, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

45. pSL1180-HR-PUbECFP

    Plasmid

    #47917

    Purpose

    Donor plasmid for homologous recombination that expresses ECFP consitutively using the Aedes aegypti polyubiquitin (PUb) promoter.

    Depositor

    Leslie Vosshall

    Insert

    ECFP
    

    Use

    Tags

    NLS

    Expression

    Insect

    Mutation

    Promoter

    Aedes aegypti polyubiquitin (PUb)

    Available since

    Sept. 26, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

46. mTagRFP-T2-PCNA-19

    Plasmid

    #58043

    Purpose

    Localization: Nucleus, Excitation: 555, Emission: 584

    Depositor

    Michael Davidson

    Insert

    PCNA (PCNA Human)
    

    Use

    Tags

    mTagRFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Nov. 4, 2014

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

47. PX380 Treponema denticola Cas9

    Plasmid

    #68317

    Purpose

    Treponema denticola Cas9

    Depositor

    Feng Zhang

    Insert

    TdCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 26, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

48. TC9nickpAB

    Plasmid

    #71311

    Purpose

    used as a template for in vitro transcription of Cas9 nickase mRNA after linearizing with BbsI

    Depositor

    Karl Degenhardt

    Insert

    Cas9 nickase
    

    Use

    In vitro transcription

    Tags

    NLS

    Expression

    Mutation

    D10A nickase

    Promoter

    T7

    Available since

    Dec. 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

49. pSBtet-RB-PE2

    Plasmid

    #173903

    Purpose

    SB-transposon with inducible expression of SpCas9 PE2

    Depositor

    Ronald Cohn

    Insert

    PE2
    

    Use

    CRISPR

    Tags

    SV40 NLS

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

50. ipUSEPR-sg-Hs-PHGDH-int2

    Plasmid

    #188682

    Purpose

    control sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgPHGDH intron control (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge