We narrowed to 378 results for: 52961

1. lentiCRISPR v2

   Plasmid

   #52961

   Purpose

   Replaces original lentiCRISPRv1 (Addgene Plasmid 49535) and produces ~10-fold higher titer virus. 3rd generation lentiviral backbone.

   Depositor

   Feng Zhang

   Publication

   Sanjana et al Nat Methods. 2014 Aug;11(8):783-4. doi:

   Inserts

   Cas9
   Puromycin resistance
   

   Use

   CRISPR and Lentiviral

   Tags

   FLAG

   Expression

   Mammalian

   Promoter

   EFS-NS

   Available since

   Availability

   Academic Institutions and Nonprofits only

   Cited by

   3707 Articles

   

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These results may also be relevant.

1. pLentiCRISPRv2-sgFXN-2

   Plasmid

   #246018

   Purpose

   All-in-one CRISPRko plasmid containing Cas9 and guide RNA targeting FXN

   Depositor

   Vamsi Mootha

   Publication

   Ast et al Cell. 2019 May 30;177(6):1507-1521.e16.

   Insert

   Frataxin (FXN Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available since

   Oct. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. LENTICRISPR-HK2_sgRNA1

   Plasmid

   #201596

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Publication

   Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

   Insert

   HK2 (HK2 Human)
   

   Use

   CRISPR and Lentiviral

   Available since

   July 26, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. LENTICRISPR-PGAM1_sgRNA2

   Plasmid

   #201615

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Publication

   Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

   Insert

   PGAM1 (PGAM1 Human)
   

   Use

   CRISPR and Lentiviral

   Available since

   June 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. LENTICRISPR-TYMS_sgRNA1

   Plasmid

   #201628

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Publication

   Skinner et al Nat Metab. 2023 May;5(5):765-776. doi: 1

   Insert

   TYMS (TYMS Human)
   

   Use

   CRISPR and Lentiviral

   Available since

   June 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. LCV2_AAVS1_sgRNA_3

   Plasmid

   #155089

   Purpose

   lentiviral plasmid expressing Cas9 and gRNA targeting AAVS1 safe harbor locus

   Depositor

   Jason Moffat

   Publication

   Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

   Insert

   AAVS1_sgRNA_3
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6 promoter

   Available since

   Aug. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLentiCriprV2-sgRNA-PER1-#1

   Plasmid

   #189987

   Purpose

   Lentiviral Cas9/sgRNA vector targeting C-terminus of hPER1, works with Addgene 189979-189982

   Depositor

   Achim Kramer

   Publication

   Gabriel et al Proc Natl Acad Sci U S A. 2024 Aug 20;12

   Insert

   Period1 (PER1 Human)
   

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. LENTICRISPR-TKT_sgRNA2

   Plasmid

   #201625

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Publication

   Skinner et al Nat Metab. 2023 May;5(5):765-776. doi: 1

   Insert

   TKT (TKT Human)
   

   Use

   CRISPR and Lentiviral

   Available since

   July 26, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. LENTICRISPR-TKT_sgRNA1

   Plasmid

   #201624

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Publication

   Skinner et al Nat Metab. 2023 May;5(5):765-776. doi: 1

   Insert

   TKT (TKT Human)
   

   Use

   CRISPR and Lentiviral

   Available since

   July 26, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. LENTICRISPR-TPI1_sgRNA1

   Plasmid

   #201626

   Purpose

   CRISPR/Cas9-mediated gene knock-out

   Depositor

   Alexis Jourdain, Vamsi Mootha

   Publication

   Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

   Insert

   TPI1 (TPI1 Human)
   

   Use

   CRISPR and Lentiviral

   Available since

   June 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. LENTICRISPR-TPI1_sgRNA2

    Plasmid

    #201627

    Purpose

    CRISPR/Cas9-mediated gene knock-out

    Depositor

    Alexis Jourdain, Vamsi Mootha

    Publication

    Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

    Insert

    TPI1 (TPI1 Human)
    

    Use

    CRISPR and Lentiviral

    Available since

    June 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. LENTICRISPR-ALDOA_sgRNA2

    Plasmid

    #201591

    Purpose

    CRISPR/Cas9-mediated gene knock-out

    Depositor

    Alexis Jourdain, Vamsi Mootha

    Publication

    Skinner et al Nat Metab. 2023 May;5(5):765-776. doi: 1

    Insert

    ALDOA (ALDOA Human)
    

    Use

    CRISPR and Lentiviral

    Available since

    June 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. LENTICRISPR-HNRNPD_sgRNA1

    Plasmid

    #201598

    Purpose

    CRISPR/Cas9-mediated gene knock-out

    Depositor

    Alexis Jourdain, Vamsi Mootha

    Publication

    Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

    Insert

    HNRNPD (HNRNPD Human)
    

    Use

    CRISPR and Lentiviral

    Available since

    June 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. LENTICRISPR-PABPC1_sgRNA1

    Plasmid

    #201608

    Purpose

    CRISPR/Cas9-mediated gene knock-out

    Depositor

    Alexis Jourdain, Vamsi Mootha

    Publication

    Jourdain et al Mol Cell. 2021 May 6;81(9):1905-1919.e12

    Insert

    PABPC1 (PABPC1 Human)
    

    Use

    CRISPR and Lentiviral

    Available since

    June 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. LentiCRISPRv2hyg-Ptgs1

    Plasmid

    #170299

    Purpose

    A knock-out vector for the mouse Ptgs1

    Depositor

    Michiyuki Matsuda

    Publication

    Konishi et al Cancer Res. 2021 May 25. pii: 0008-5472.

    Insert

    A gRNA targeting the mouse Ptgs1 gene.
    

    Use

    CRISPR and Lentiviral

    Available since

    July 8, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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15. LCV2_PSMB2_sgRNA_1

    Plasmid

    #155092

    Purpose

    lentiviral plasmid expressing Cas9 and gRNA targeting PSMB2 (core essential gene)

    Depositor

    Jason Moffat

    Publication

    Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

    Insert

    PSMB2_sgRNA_1 (PSMB2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6 promoter

    Available since

    Aug. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLENTICRISPR V2 sgCGAS_1

    Plasmid

    #241454

    Purpose

    Delete CGAS

    Depositor

    Richard Possemato

    Insert

    sgCGAS_1 (CGAS Synthetic)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available since

    Nov. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pLentiCRISPR V2 SLC31A1_sg2

    Plasmid

    #244870

    Purpose

    Knockout of human SLC31A1

    Depositor

    Alexis Jourdain

    Publication

    Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

    Insert

    SLC31A1 sgRNA (SLC31A1 Human)
    

    Use

    CRISPR and Lentiviral

    Promoter

    U6

    Available since

    Oct. 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLentiCRISPR V2 SLC31A1_sg1

    Plasmid

    #244869

    Purpose

    Knockout of human SLC31A1

    Depositor

    Alexis Jourdain

    Publication

    Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

    Insert

    SLC31A1 sgRNA (SLC31A1 Human)
    

    Use

    CRISPR and Lentiviral

    Promoter

    U6

    Available since

    Oct. 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. LENTICRISPR-GPI_sgRNA1

    Plasmid

    #201594

    Purpose

    CRISPR/Cas9-mediated gene knock-out

    Depositor

    Alexis Jourdain, Vamsi Mootha

    Publication

    Skinner et al Nat Metab. 2023 May;5(5):765-776. doi: 1

    Insert

    GPI (GPI Human)
    

    Use

    CRISPR and Lentiviral

    Available since

    June 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. MS2-adRNA (5'UAG)

    Plasmid

    #170126

    Purpose

    Lentiviral vector carrying 2 copies of the MS2 adRNA targeting a UAG at the 5' end of the ADAR2 deaminase domain in plasmids #170124 and 170125

    Depositor

    Prashant Mali

    Publication

    Katrekar et al Elife. 2022 Jan 19;11. pii: 75555. doi:

    Insert

    MS2-ADAR2(5'UAG)-MS2
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    Human U6 and mouse U6

    Available since

    Jan. 4, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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