We narrowed to 13 results for: 52961

1. Mouse SLC KO Library

   Pooled Library

   #141436

   Purpose

   Expresses gRNAs for knockout of the mouse Solute Carrier family

   Depositor

   Giulio Superti-Furga

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   May 18, 2020

   Availability

   Academic Institutions and Nonprofits only

2. Human ubiquitination-related proteins CRISPR KO library

   Pooled Library

   #174592

   Purpose

   CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

   Depositor

   Juan Bonifacino

   Article

   Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 30, 2021

   Availability

   Academic Institutions and Nonprofits only

3. The Human Druggable CRISPR library

   Pooled Library

   #200013

   Purpose

   The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

   Depositor

   Lianxin Liu

   Article

   Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 9, 2023

   Availability

   Academic Institutions and Nonprofits only

4. RNA-binding protein pooled CRISPR knockout library

   Pooled Library

   #141438

   Purpose

   CRISPR knockout library targets RBPs with 10 sgRNAs/gene

   Depositor

   Eugene Yeo

   Article

   Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 28, 2020

   Availability

   Academic Institutions and Nonprofits only

5. Human sgRNA library Brunello in lentiCRISPRv2

   Pooled Library

   #73179

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

6. Mouse metabolism knockout library

   Pooled Library

   #160129

   Purpose

   CRISPR library targets mouse metabolic genes

   Depositor

   Kivanc Birsoy

   Article

   Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 10, 2020

   Availability

   Academic Institutions and Nonprofits only

7. MYC-CRISPR

   Pooled Library

   #173195

   Purpose

   This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

   Depositor

   Agnieszka Dzikiewicz-Krawczyk

   Article

   Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

8. Human Epigenetic Knockout Library

   Pooled Library

   #162256

   Purpose

   Lentiviral CRISPR library targets human epigenetic genes

   Depositor

   Kivanc Birsoy

   Article

   Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

9. Human SLC KO Library

   Pooled Library

   #132552

   Purpose

   Expresses gRNAs for knockout of the human Solute Carrier family

   Depositor

   Giulio Superti-Furga

   Article

   Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 7, 2020

   Availability

   Academic Institutions and Nonprofits only

10. Liu Lab MusCK Library A

    Pooled Library

    #174196

    Purpose

    MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

    Depositor

    Xiaole Shirley Liu

    Article

    Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Liu Lab MusCK Library B

    Pooled Library

    #174197

    Purpose

    MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

    Depositor

    Xiaole Shirley Liu

    Article

    Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

12. Toronto KnockOut version 3 library (TKOv3)

    Pooled Library

    #90294

    Purpose

    Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

    Depositor

    Jason Moffat

    Article

    Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

    Available since

    May 5, 2017

    Availability

    Academic Institutions and Nonprofits only

13. Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

    Pooled Library

    #159392

    Purpose

    Mouse lentiviral genome-wide CRISPR library

    Depositor

    Jason Moffat

    Article

    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Nov. 9, 2020

    Availability

    Academic Institutions and Nonprofits only