We narrowed to 369 results for: SYN1

1. pAAV2-hSyn1-NES-ChemoG-CaM

   Plasmid

   #193817

   Purpose

   Expression of ChemoG-CaM in primary neurons

   Depositor

   Julien Hiblot

   Article

   Hellweg et al Nat Chem Biol. 2023 Jun 8. doi: 10.1038/

   Insert

   ChemoG-CaM
   

   Use

   AAV

   Tags

   Expression

   Mutation

   EGFP:A206K; HT7: L271E

   Promoter

   hSyn1

   Available Since

   June 9, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. pOTTC533 - pAAV SYN1 eGFP-2A-mKv1.2

   Plasmid

   #75295

   Purpose

   An AAV packaging vector that expresses eGFP and Kv1.2 under the control of a neuronal promoter.

   Depositor

   Brandon Harvey

   Insert

   eGFP-2A-mKv1.2 (Kcna2 Synthetic, Mouse)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   human SYN1

   Available Since

   Jan. 22, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV hSyn1 CaRhAC T2A tDimer

   Plasmid

   #101722

   Purpose

   - humanized - variant of pAAV hSyn YFP-CaRhAC Addgene # 101721– less reliable in hippocampal neurons

   Depositor

   Thomas Oertner

   Article

   Scheib et al Nat Commun. 2018 May 24;9(1):2046. doi:

   Inserts

   CatRhAC
   red fluorescent protein
   

   Use

   AAV

   Tags

   Expression

   Mutation

   E497K,C569D

   Promoter

   human Synapsin1 promotor and ribosomal skip seque…

   Available Since

   Jan. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pOTTC1617 pAAV SYN1 Nuc-EYFP

   Plasmid

   #135567

   Purpose

   An AAV vector expressing a neuronally expressed nuclear EYFP reporter

   Depositor

   Christopher Richie

   Article

   Venniro et al Proc Natl Acad Sci U S A. 2020 Apr 7;117

   Inserts

   empty
   Nuc-EYFP
   

   Use

   AAV

   Tags

   3xNLS

   Expression

   Mammalian

   Mutation

   Promoter

   hSYN1

   Available Since

   Sept. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV-hSyn1-DIO-ExRai-AKAR2-T/A

   Plasmid

   #171847

   Purpose

   Cre-dependent, synapsin promoter-driven expression of the negative control phosphomutant ExRai-AKAR2 T/A PKA biosensor in neurons.

   Depositor

   Richard Huganir

   Article

   Zhang et al Nat Chem Biol. 2020 Sep 28. pii: 10.1038

   Insert

   ExRai-AKAR2 T/A
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   T6A phospho-deficient mutation

   Promoter

   hSyn1

   Available Since

   July 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. AAV-U6-sgLacZ-U6-sgGFP-hSyn1-mCherry

   Plasmid

   #208834

   Purpose

   Control plasmid expresses mCherry under the hSyn1 promoter with sgRNAs against LacZ and GFP

   Depositor

   Ben Emery

   Article

   Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

   Insert

   mCherry
   

   Use

   AAV and CRISPR

   Tags

   Expression

   Bacterial and Mammalian

   Mutation

   Promoter

   hSyn1

   Available Since

   Oct. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. AAV-U6-sgMap3K12(1)-U6-sgMap3K12(2)-hSyn1-mCherry

   Plasmid

   #208835

   Purpose

   Knockout of Map3K12 (DLK) using tandem sgRNAs, expresses mCherry under the hSyn1 promoter

   Depositor

   Ben Emery

   Article

   Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

   Insert

   mCherry
   

   Use

   AAV and CRISPR

   Tags

   Expression

   Bacterial and Mammalian

   Mutation

   Promoter

   hSyn1

   Available Since

   Oct. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. AAV-U6-sgMap3K13(1)-U6-sgMap3K13(2)-hSyn1-mCherry

   Plasmid

   #208836

   Purpose

   Knockout of Map3K13 (LZK) using tandem sgRNAs, expresses mCherry under the hSyn1 promoter

   Depositor

   Ben Emery

   Article

   Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

   Insert

   mCherry
   

   Use

   AAV and CRISPR

   Tags

   Expression

   Bacterial and Mammalian

   Mutation

   Promoter

   hSyn1

   Available Since

   Oct. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. AAV-U6-sgMap3K13(1)-U6-sgMap3K12(1)-hSyn1-mCherry

   Plasmid

   #208837

   Purpose

   Knockout of Map3K12 (DLK) and Map3K13 (LZK) using tandem sgRNAs, expresses mCherry under the hSyn1 promoter

   Depositor

   Ben Emery

   Article

   Duncan et al Nat Commun. 2024 Oct 23;15(1):9148. doi:

   Insert

   mCherry
   

   Use

   AAV and CRISPR

   Tags

   Expression

   Bacterial and Mammalian

   Mutation

   Promoter

   hSyn1

   Available Since

   Oct. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLenti-hSyn1-ChR2(H134R)-EYFP

    Plasmid

    #197593

    Purpose

    Lentiviral transfer vector for the neuronal expression of ChR2(H134R)-EYFP (Channelrhodopsin for the inducing neuronal activity)

    Depositor

    Patrik Verstreken

    Insert

    ChR2(H134R)-EYFP
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    hSynI

    Available Since

    April 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pOTTC814 - pAAV-SYN1-CRTsigpep-GCaMP3 (D324G+D360G+397G+D435G 10.19)-KDEL

    Plasmid

    #63887

    Purpose

    An AAV packaging vector that expresses ER-retained low-affinity GCaMP3 variant under control of the SYN1 promoter.

    Depositor

    Brandon Harvey

    Article

    Henderson et al PLoS One. 2015 Oct 9;10(10):e0139273. do

    Insert

    ER-localized low-affinity GCaMP3(10.19)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    human SYN1

    Available Since

    Dec. 1, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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12. AAV-hSyn1-GCaMP6f-P2A-nls-dTomato

    Plasmid

    #51085

    Purpose

    Neuronal expression of GCaMP6f Ca sensor and physically separate nuclear localized dTomato fluorophore

    Depositor

    Jonathan Ting

    Has Service

    AAV Retrograde and AAV1

    Insert

    GCaMP6f
    

    Use

    AAV

    Tags

    P2A-nls-dTomato

    Expression

    Mammalian

    Mutation

    Promoter

    human Synapsin1

    Available Since

    Feb. 27, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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13. AAV-hSyn1-GCaMP6s-P2A-nls-dTomato

    Plasmid

    #51084

    Purpose

    Neuronal expression of GCaMP6s Ca sensor and physically separate nuclear localized dTomato fluorophore

    Depositor

    Jonathan Ting

    Has Service

    AAV Retrograde and AAV1

    Insert

    GCaMP6s
    

    Use

    AAV

    Tags

    P2A-nls-dTomato

    Expression

    Mammalian

    Mutation

    Promoter

    human Synapsin1

    Available Since

    Feb. 27, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-Syn1-fDIO-mScarlet-KASH-2a-Cre

    Plasmid

    #203838

    Purpose

    Flp-dependent Cre and mScarlet-KASH expression

    Depositor

    Ivo Spiegel

    Article

    Roethler et al Neuron. 2023 Jun 20:S0896-6273(23)00399-

    Insert

    Cre
    

    Use

    AAV

    Tags

    mScarlet-KASH-2A

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-hSyn1-SIO-eOPN3-mScarlet-WPRE

    Plasmid

    #125713

    Purpose

    Cre-dependent vector expressing an optimized mosquito OPN3 rhodopsin in-frame with mScarlet

    Depositor

    Ofer Yizhar

    Article

    Mahn et al Neuron. 2021 May 10. pii: S0896-6273(21)

    Has Service

    AAV1 and AAV5

    Insert

    eOPN3
    

    Use

    AAV and Cre/Lox

    Tags

    Rho1D4 and mScarlet

    Expression

    Mammalian

    Mutation

    deleted amino acids 331-429

    Promoter

    hSyn1

    Available Since

    Sept. 20, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. PZac2.1 hSyn1-Lck-13xLinker-BioID2-BioID2-HA

    Plasmid

    #176854

    Purpose

    Expresses membrane bound biotin ligase, BioID2, in neurons

    Depositor

    Baljit Khakh

    Article

    Soto et al Nature. 2023 Apr;616(7958):764-773. doi:

    Insert

    Lck-13xLinker-BioID2-BioID2-HA
    

    Use

    AAV

    Tags

    HA

    Expression

    Bacterial

    Mutation

    Promoter

    hSyn1

    Available Since

    April 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-Syn1-fDIO-mScarlet-KASH-2a-dCre

    Plasmid

    #203839

    Purpose

    Flp-dependent enzymatically inactive Cre and mScarlet-KASH expression

    Depositor

    Ivo Spiegel

    Article

    Roethler et al Neuron. 2023 Jun 20:S0896-6273(23)00399-

    Insert

    dCre
    

    Use

    AAV

    Tags

    mScarlet-KASH-2A

    Expression

    Mutation

    Enzymatically inactive Cre

    Promoter

    Available Since

    Aug. 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAAV-hSyn1-DIO-Opto-cytTrkB(E281A)-HA

    Plasmid

    #180590

    Purpose

    Opto-cytTrkB

    Depositor

    Won Do Heo

    Article

    Hong J et al J Mol Biol. 2020 Feb 14;432(4):815-827.

    Insert

    TrkB
    

    Use

    AAV

    Tags

    Expression

    Mutation

    PHR(E281A)

    Promoter

    Available Since

    Feb. 28, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV hSyn1 bPAC cMyc S27A 2A tDimer

    Plasmid

    #85398

    Purpose

    humanized photoactivated adenylyl cyclase lower dark activity, spectrum shifted 15 nm longer wavelenght with neuron-specific promoter, plus red fluorescent protein

    Depositor

    Thomas Oertner

    Inserts

    humanized photoactivated adenylyl cyclase
    red fluorescent protein
    

    Use

    AAV

    Tags

    cMyc Tag

    Expression

    Mammalian

    Mutation

    S27A

    Promoter

    human Synapsin1 promotor and ribosomal skip seque…

    Available Since

    Jan. 2, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV hSyn1 bPAC cMyc T2A tDimer

    Plasmid

    #85397

    Purpose

    humanized photoactivated adenylyl cyclase with cMyc Tag driven by neuron-specific promoter, plus red fluorescent protein

    Depositor

    Thomas Oertner

    Inserts

    humanized photoactivated adenylyl cyclase
    red fluorescent protein
    

    Use

    AAV

    Tags

    cMyc Tag

    Expression

    Mammalian

    Mutation

    Promoter

    human synapsin-1 and ribosomal skip sequence T2A

    Available Since

    Jan. 2, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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