We narrowed to 32,518 results for: Eng

1. AAV phSyn1(S)-DreO-bGHpA

   Plasmid

   #50363

   Purpose

   Can be used to generate AAV virus that will express DreO recombinase in neurons from the synapsin promoter

   Depositor

   Hongkui Zeng

   Article

   Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

   Has Service

   AAV Retrograde and AAV5

   Insert

   DreO recombinase
   

   Use

   AAV

   Tags

   none

   Mutation

   Sequence optimized for expression in mammalian ce…

   Promoter

   hSyn1

   Available Since

   Jan. 16, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-EF1a-CCreV

   Plasmid

   #140132

   Purpose

   can be used to generate AAV virus that will express fusion protein of split Cre (C-terminal) and fungal photoreceptor Vivid (VVD) monomer

   Depositor

   Hongkui Zeng

   Article

   Yao et al Nat Methods. 2020 Mar 23. pii: 10.1038/s

   Insert

   CCreV
   

   Use

   AAV

   Promoter

   EF1a

   Available Since

   April 23, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pAAV-EF1a-NCreV

   Plasmid

   #140131

   Purpose

   can be used to generate AAV virus that will express fusion protein of split Cre (N-terminal) and fungal photoreceptor Vivid (VVD) monomer

   Depositor

   Hongkui Zeng

   Article

   Yao et al Nat Methods. 2020 Mar 23. pii: 10.1038/s

   Insert

   NCreV
   

   Use

   AAV

   Promoter

   EF1a

   Available Since

   April 23, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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4. Slc17a7-IRES2-Cre targeting vector

   Plasmid

   #61574

   Purpose

   Target the Cre recombinase gene to the stop codon of the mouse Slc17a7 (VGlut1) gene

   Depositor

   Hongkui Zeng

   Article

   Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

   Insert

   Slc17a7-IRES2-Cre
   

   Use

   Cre/Lox and Mouse Targeting

   Available Since

   July 30, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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5. AAV pCAG-FLEX2-tTA2-WPRE-bGHpA

   Plasmid

   #65458

   Purpose

   Can be used to generate AAV virus that will express the tetracycline transactivator tTA2 from the CAG promoter in a Cre-dependent manner

   Depositor

   Hongkui Zeng

   Article

   Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

   Insert

   tTA2
   

   Use

   AAV

   Promoter

   CAG

   Available Since

   July 7, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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6. pDisplay-GRAB-HaloDAmut-IRES-EGFP-CAAX

   Plasmid

   #234411

   Purpose

   Expresses the chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut and a membrane-localized EGFP in mammalian cells

   Depositor

   Yulong Li

   Article

   Zheng et al Science. 2025 Jun 5;388: 6751. doi: http

   Insert

   GPCR activation based chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   June 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. AAV pCAG-FSF-FLEX-EGFP-WPRE-bGHpA

   Plasmid

   #65455

   Purpose

   Can be used to generate AAV virus that will express EGFP from the CAG promoter under intersectional control by Flp and Cre recombinases

   Depositor

   Hongkui Zeng

   Article

   Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

   Insert

   EGFP
   

   Use

   AAV

   Promoter

   CAG

   Available Since

   July 7, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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8. Pvalb-2A-Flpo Flp-in replacement vector

   Plasmid

   #61572

   Purpose

   Recombinase-mediated cassette exchange in ES cells to insert the Flpo recombinase gene at the mouse Pvalb gene stop codon

   Depositor

   Hongkui Zeng

   Article

   Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

   Insert

   Pvalb-2A-Flpo
   

   Use

   Recombinase-mediated cassette exchange using flp …

   Available Since

   Feb. 9, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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9. Snap25-LSL-2A-GFP targeting vector

   Plasmid

   #61575

   Purpose

   Target a Cre-dependent GFP expression cassette to the stop codon of the mouse Snap25 gene

   Depositor

   Hongkui Zeng

   Article

   Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

   Insert

   Snap25-LSL-2A-GFP
   

   Use

   Cre/Lox and Mouse Targeting

   Available Since

   Feb. 9, 2015

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. AAV pTRE-FSF-FLEX-EGFP-WPRE-bGHpA

    Plasmid

    #65453

    Purpose

    Can be used to generate AAV virus that will express EGFP from the tetO promoter under intersectional control by Flp and Cre recombinases

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Has Service

    AAV1

    Insert

    EGFP
    

    Use

    AAV

    Promoter

    tetO

    Available Since

    Jan. 28, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. AAV phSyn1(S)-FlpE-bGHpA

    Plasmid

    #50364

    Purpose

    Can be used to generate AAV virus that will express FlpE recombinse gene in neurons from the synapsin promoter

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    FlpE recombinase gene
    

    Use

    AAV

    Promoter

    hSyn1

    Available Since

    Jan. 16, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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12. pBoBi-hPEN2 D90A

    Plasmid

    #183641

    Purpose

    Lentiviral expression of a PEN2 mutant losing its binding affinity to metformin at the C-terminus (lysosome lumen).

    Depositor

    Sheng-cai Lin

    Article

    Ma et al Nature. 2022 Mar;603(7899):159-165. doi:

    Insert

    PEN2 (PSENEN Human)
    

    Use

    Lentiviral

    Tags

    HA

    Mutation

    residues 90 of PEN2 mutated to alanine

    Promoter

    CMV

    Available Since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. pBoBi-hPEN2 2A

    Plasmid

    #183640

    Purpose

    Lentiviral expression of a PEN2 mutant losing its binding affinity to metformin at the N-terminus (cytosolic face).

    Depositor

    Sheng-cai Lin

    Article

    Ma et al Nature. 2022 Mar;603(7899):159-165. doi:

    Insert

    PEN2 (PSENEN Human)
    

    Use

    Lentiviral

    Tags

    HA

    Mutation

    residues 35 and 40 of PEN2 mutated to alanine

    Promoter

    CMV

    Available Since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. AAV phSyn1-RSR-FLEX-ChR2(H134R)-EYFP-WPRE-bGHpA

    Plasmid

    #65429

    Purpose

    Can be used to generate AAV virus that will express the ChR2(H134R)-EYFP channelrhodopsin fusion protein in neurons under intersectional control by Dre and Cre recombinases

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    EYFP

    Mutation

    H134R variant

    Promoter

    hSyn1

    Available Since

    July 17, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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15. Ai62(TITL-tdT) Flp-in replacement vector

    Plasmid

    #61576

    Purpose

    Recombinase-mediated cassette exchange in ES cells to insert a Cre & tTA-dependent tdTomato expression cassette into a docking site within the mouse TIGRE genomic locus

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    chromatin insulator flanked TRE-LSL-tdTomato
    

    Use

    Recombinase-mediated cassette exchange using flp …

    Available Since

    March 18, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. Rasgrf2-2A-dCre targeting vector

    Plasmid

    #61573

    Purpose

    Target a DHFR-destabilized Cre recombinase gene to the stop codon of the mouse Rasgrf2 gene

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    Rasgrf2-2A-dCre (Rasgrf2 Mouse, P1 bacteriophage)
    

    Use

    Cre/Lox and Mouse Targeting

    Available Since

    March 31, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pBoBi-hGOLGA2-C-PEN2

    Plasmid

    #183649

    Purpose

    Lentiviral expression of a golgi-residential PEN2.

    Depositor

    Sheng-cai Lin

    Article

    Ma et al Nature. 2022 Mar;603(7899):159-165. doi:

    Insert

    PEN2 and GOLGA2 (PSENEN, GOLGA2 Human)
    

    Use

    Lentiviral

    Tags

    HA

    Mutation

    WT

    Promoter

    CMV

    Available Since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. AAV phSyn1(S)-FlpO-bGHpA

    Plasmid

    #51669

    Purpose

    Can be used to generate AAV virus that will express the FlpO recombinase gene in neurons from the synapsin promoter.

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Has Service

    AAV Retrograde

    Insert

    FlpO recombinase gene
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    hSyn1

    Available Since

    May 2, 2014

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. AAV phSyn1-FSF-FLEX-ChR2(H134R)-EYFP-WPRE-bGHpA

    Plasmid

    #65454

    Purpose

    Can be used to generate AAV virus that will express the ChR2(H134R)-EYFP channelrhodopsin fusion protein in neurons under intersectional control by Flp and Cre recombinases

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    EYFP

    Mutation

    H134R variant

    Promoter

    hSyn1

    Available Since

    July 7, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pBoBi-hLAMP2-C-PEN2

    Plasmid

    #183646

    Purpose

    Lentiviral expression of a lysosome-residential PEN2.

    Depositor

    Sheng-cai Lin

    Article

    Ma et al Nature. 2022 Mar;603(7899):159-165. doi:

    Insert

    PEN2 and LAMP2 (PSENEN, LAMP2 Human)
    

    Use

    Lentiviral

    Tags

    HA

    Mutation

    WT

    Promoter

    CMV

    Available Since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge