We narrowed to 22,533 results for: Sis;

1. Tol2-LyzC-Rac-CA(guide resistant)-2a-mcherry-U6ac-Rac guides

   Plasmid

   #168244

   Purpose

   "Rescue Rac-CA expression in neutrophil specific knockout"

   Depositor

   Qing Deng

   Article

   Wang et al J Cell Sci. 2021 Apr 15;134(8). pii: 237

   Insert

   Rac(guide resistant)-CA
   

   Use

   Zebrafish expression

   Tags

   mcherry

   Expression

   Mutation

   Promoter

   LyzC

   Available since

   March 16, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLenti-Ef1a-mClover-W377A/W428A YTHDC1-T2A-BSD-siRNA-Resistant

   Plasmid

   #177130

   Purpose

   Generate lentivirus to introduce mClover tagged m6A binding null mutant W377A/W428A YTHDC1

   Depositor

   Wenbo Li

   Article

   Lee et al Mol Cell. 2021 Aug 19;81(16):3368-3385.e

   Insert

   YTHDC1 (YTHDC1 Human)
   

   Use

   Lentiviral

   Tags

   mClover3

   Expression

   Mutation

   W428A/W377A (m6A binding defects), and siRNA resi…

   Promoter

   Ef1a

   Available since

   July 7, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. WNV strain-NY99 NS2B-NS3 protease fusion with non cleavable linker with mutation K to A to reduce autoproteolysis

   Plasmid

   #228660

   Purpose

   Bacterial expression of the fusion of the NS2B-NS3 protease from West Nile virus with an H163A - catalytically inactive mutation for xxxxx

   Depositor

   ASAP Discovery, Frank von Delft

   Insert

   West Nile portion of NS2B protease fused to NS3
   

   Use

   Tags

   His-Twin Strep-Tev

   Expression

   Bacterial

   Mutation

   H163A - catalytically inactive/West Nile Virus NS…

   Promoter

   Available since

   Feb. 18, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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4. siRNA-resistant SigmaR1-mNeonGreen a5mut (F196A L199A F200A L203A Y206A L210A L214A Y217A)

   Plasmid

   #226578

   Purpose

   Encodes mutant siRNA resistant SigmaR1 protein (substitutions) labeled with mNeonGreen

   Depositor

   Gia Voeltz

   Article

   Sawyer et al Dev Cell. 2024 Jul 2:S1534-5807(24)00382

   Insert

   SigmaR1 (Sigma-1 Receptor) (SIGMAR1 Human)
   

   Use

   Tags

   mNeonGreen

   Expression

   Mammalian

   Mutation

   F196A, L199A, F200A, L203A, Y206A, L210A, L214A, …

   Promoter

   Available since

   Nov. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pcDNA3-Flag-Tpr-Si

   Plasmid

   #60918

   Purpose

   Expresses Flag tagged nucleoporin Tpr resistant to siRNA GCACAACAGGATAAGGTTA

   Depositor

   Vinay Nandicoori

   Article

   Rajanala et al PLoS One. 2012;7(1):e29921. doi: 10.1371

   Insert

   TPR (TPR Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Silent point mutations in siRNA target region; E1…

   Promoter

   CMV

   Available since

   Jan. 5, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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6. PCR4-Hsp68::mCherry-SI-Hsp68::eGFP-H11

   Plasmid

   #211942

   Purpose

   dual-enSERT-2.2 vector for site-specific integration of.a two-color enhancer-reporter construct into the H11 locus (separated by a synthetic insulator)

   Depositor

   Evgeny Kvon

   Article

   Hollingsworth et al Nat Commun. 2025 Jan 6;16(1):409. doi: 1

   Type

   Empty backbone

   Use

   CRISPR and Mouse Targeting

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   HSP68

   Available since

   March 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. PCR4-HBGP::mCherry-SI-HBGP::eGFP-H11

   Plasmid

   #216394

   Purpose

   dual-enSERT-2.2 vector for site-specific integration of.a two-color enhancer-reporter construct (human beta-globin promoter) into the H11 locus (separated by a synthetic insulator)

   Depositor

   Evgeny Kvon

   Article

   Hollingsworth et al Nat Commun. 2025 Jan 6;16(1):409. doi: 1

   Type

   Empty backbone

   Use

   CRISPR and Mouse Targeting

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Human beta-globin

   Available since

   March 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. lentiCas9-Blast (Lentiviral Prep)

   Viral Prep

   #52962-LV

   Purpose

   Ready-to-use Lentiviral Prep particles produced from lentiCas9-Blast (#52962). In addition to the viral particles, you will also receive purified lentiCas9-Blast plasmid DNA. Lentiviral particles carrying Cas9 and blasticidin resistance. This virus is used to make stable cell lines expressing Cas9.

   Depositor

   Feng Zhang

   Article

   Sanjana et al Nat Methods. 2014 Aug;11(8):783-4. doi:

   Promoter

   EFS-NS

   Tags

   None

   Available since

   July 14, 2016

   Availability

   Academic Institutions and Nonprofits only

9. pAAV.GFA104.PI.eGFP.WPRE.bGH (AAV5)

   Viral Prep

   #100896-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV.GFA104.PI.eGFP.WPRE.bGH (#100896). In addition to the viral particles, you will also receive purified pAAV.GFA104.PI.eGFP.WPRE.bGH plasmid DNA. GFA104-driven eGFP expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Philip Haydon

   Article

   Ortinski et al Nat Neurosci. 2010 May;13(5):584-91. doi

   Promoter

   GFA104 (GFAP promoter)

   Tags

   EGFP

   Available since

   April 6, 2018

   Availability

   Academic Institutions and Nonprofits only

10. pAAV/D377Y-mPCSK9 (AAV8)

    Viral Prep

    #58376-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV/D377Y-mPCSK9 (#58376). In addition to the viral particles, you will also receive purified pAAV/D377Y-mPCSK9 plasmid DNA. hAAT-driven expression of mutant (D377Y) murine PCSK9. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jacob Bentzon

    Article

    Bjorklund et al Circ Res. 2014 May 23;114(11):1684-9. do

    Promoter

    HCRApoE/hAAT

    Tags

    None

    Available since

    July 30, 2025

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-CaMKIIa-hChR2(E123A)-EYFP (AAV9)

    Viral Prep

    #35505-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(E123A)-EYFP (#35505). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(E123A)-EYFP plasmid DNA. CaMKIIa-driven hChR2(E123A)-EYFP expression for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

    Promoter

    CaMKII

    Tags

    EYFP

    Available since

    May 24, 2018

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-DIO-EF1α-mKate2-PDE4D3-Cat (AAV1)

    Viral Prep

    #169128-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-DIO-EF1α-mKate2-PDE4D3-Cat (#169128). In addition to the viral particles, you will also receive purified pAAV-DIO-EF1α-mKate2-PDE4D3-Cat plasmid DNA. EF1a-driven, Cre-dependent expression of truncated PDE4D3 and mKate2. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Georg Nagel

    Article

    Zhang et al Nature. 2021 Sep;597(7875):245-249. doi:

    Promoter

    EF1a

    Tags

    None

    Available since

    Aug. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-CaMKIIa-hChR2(E123A)-mCherry (AAV9)

    Viral Prep

    #35506-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(E123A)-mCherry (#35506). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(E123A)-mCherry plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin E123A mutant fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

    Promoter

    CaMKII

    Tags

    mCherry

    Available since

    March 30, 2018

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-Ef1a-DIO hChR2(E123T/T159C)-EYFP (AAV5)

    Viral Prep

    #35509-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-Ef1a-DIO hChR2(E123T/T159C)-EYFP (#35509). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO hChR2(E123T/T159C)-EYFP plasmid DNA. EF1a-driven, Cre-dependent, humanized channelrhodopsin E123T/T159C mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

    Promoter

    EF1a

    Tags

    EYFP (Cre-dependent)

    Available since

    Feb. 21, 2018

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-Ef1a-DIO hChR2(E123T/T159C)-EYFP (AAV9)

    Viral Prep

    #35509-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-Ef1a-DIO hChR2(E123T/T159C)-EYFP (#35509). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO hChR2(E123T/T159C)-EYFP plasmid DNA. EF1a-driven, Cre-dependent, humanized channelrhodopsin E123T/T159C mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

    Promoter

    EF1a

    Tags

    EYFP (Cre-dependent)

    Available since

    Feb. 21, 2018

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-CaMKIIa-ChRmine-oScarlet-KV 2.1-WPRE (AAV8)

    Viral Prep

    #183519-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-CaMKIIa-ChRmine-oScarlet-KV 2.1-WPRE (#183519). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-ChRmine-oScarlet-KV 2.1-WPRE plasmid DNA. CaMKIIa-driven expression of ChRmine-oScarlet-KV 2.1. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Kishi et al Cell. 2022 Feb 17;185(4):672-689.e23. do

    Promoter

    CaMKII

    Tags

    None

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

17. KHBD00018

    Plasmid

    #34180

    Depositor

    Bart Deplancke

    Article

    Korneel et al Nat Methods. 2011 Oct 30;8(12):1065-70.

    Insert

    CG1641 (sisA Fly)
    

    Use

    Gateway donor vector

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 23, 2012

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-CBh-mKate2-IRES-MCS (WT-WT) (AAV2)

    Viral Prep

    #105921-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-CBh-mKate2-IRES-MCS (WT-WT) (#105921). In addition to the viral particles, you will also receive purified pAAV-CBh-mKate2-IRES-MCS (WT-WT) plasmid DNA. Control mKate2 expression AAV with two wild-type ITR sequences. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Marcella Patrick

    Promoter

    CBh and same CBh promoter as mKate2

    Tags

    mKate2

    Available since

    Nov. 13, 2018

    Availability

    Academic Institutions and Nonprofits only

19. mChF-Cav1s

    Plasmid

    #171464

    Purpose

    Expresses mChF-Cav1s, a FiCE of iCMM, in mammalian cells

    Depositor

    Takafumi Miyamoto

    Article

    Miyamoto et al Cell Rep Methods. 2021 Jul 22;1(4):10005

    Insert

    mCherry-FKBP12-Caveolin1(61-178 aa)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    July 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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20. YF-Cav1s

    Plasmid

    #171462

    Purpose

    Expresses YF-Cav1s, a FiCE of iCMM, in mammalian cells

    Depositor

    Takafumi Miyamoto

    Article

    Miyamoto et al Cell Rep Methods. 2021 Jul 22;1(4):10005

    Insert

    EYFP-FKBP12-Caveolin1(61-178 aa)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    July 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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