We narrowed to 33,617 results for: IND

1. pRSET OCaMP

   Plasmid

   #224932

   Purpose

   Expresses OCaMP, an orange calcium indicator, in bacteria. Contains T7 promoter and RSET leader sequence peptide (His tag, T7 leader, Xpress epitope)

   Depositor

   Alexander Lohman

   Article

   Aggarwal et al bioRxiv 2025.07.28.667269; doi: https://

   Insert

   OCaMP
   

   Use

   Tags

   6xHis, RSET peptide, and Xpress tag

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available Since

   July 28, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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2. pLX304 ERG R367K

   Plasmid

   #118626

   Purpose

   Overexpresses ERG R367K (DNA binding mutant) protein

   Depositor

   William Hahn

   Article

   Sandoval et al Mol Cell. 2018 Aug 16;71(4):554-566.e7.

   Insert

   ERG ( R367K DNA Binding mutant) (ERG Human)
   

   Use

   Lentiviral

   Tags

   None

   Expression

   Mammalian

   Mutation

   R367K

   Promoter

   CMV

   Available Since

   Nov. 26, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLenti-Tet-MKK6(DD)-Puro

   Plasmid

   #86094

   Purpose

   Tet/Dox inducible (TetR) constitutively active mutant MKK6/MAP2K6 in lentiviral vector

   Depositor

   Cindy Miranti

   Article

   Frank et al J Cell Sci. 2017 Apr 26. pii: jcs.197152

   Insert

   MKK6 (MAP2K6 Human)
   

   Use

   Lentiviral

   Tags

   Myc tag

   Expression

   Mammalian

   Mutation

   Serine 207 and Threonine 211 both changed to Aspa…

   Promoter

   CMV/TetO

   Available Since

   Nov. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. CDKN1A sgRNA

   Plasmid

   #138189

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDKN1A

   Depositor

   Wen Xue

   Article

   Kwan et al Hepatology. 2019 Jun 12. doi: 10.1002/he

   Insert

   CDKN1A (CDKN1A Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   March 18, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. Epac-S-H30

   Plasmid

   #170337

   Purpose

   CFP(UST)_EPACdDEPCD_Y(UST) biosensor to measure realtime changes in FRET reflecting fluctuations in cAMP levels in living cells.

   Depositor

   Kees Jalink

   Article

   Ponsioen et al EMBO Rep. 2004 Dec . 5(12):1176-80.

   Insert

   CFP(UST)_EPACdDEPCD_Y(UST) (RAPGEF3 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Deletion of DEP domain, Catalytically dead T781A …

   Promoter

   CMV

   Available Since

   Oct. 5, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. pICE-HA-Ku70-siR-Mut6E

   Plasmid

   #82330

   Purpose

   Plasmid for constitutive or doxy-inducible expression of mutant human Ku70 unable to bind DNA and resistant to siRNA. Confers resistance to puro. Use T-REx cells for doxycycline-inducible expression.

   Depositor

   Patrick Calsou, Sébastien Britton

   Article

   Lamaa et al EMBO Rep. 2016 Apr;17(4):508-18. doi: 10

   Insert

   Ku70 (XRCC6 Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   Mut6E corresponding to K282E K287E T300E K331E K3…

   Promoter

   CMV-tet

   Available Since

   Sept. 13, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. p(HA)HIF1alpha(401delta603)R27G

   Plasmid

   #52215

   Purpose

   mammalian expression of HA tagged HIF1alpha with a deletion of the N-terminal activation domain and R27G mutation

   Depositor

   Eric Huang

   Article

   Koshiji et al EMBO J. 2004 May 5;23(9):1949-56. Epub 2

   Insert

   HIF1alpha (401delta603) R27G (HIF1A Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   aa 401-603 deleted, removes the oxygen-dependent …

   Promoter

   CMV

   Available Since

   April 7, 2014

   Availability

   Academic Institutions and Nonprofits only

8. CMV-ShadowY-CBD(H83L/H86L)-P2A-Clover(T153M/F223R)-Cdc42

   Plasmid

   #165436

   Purpose

   Expresses ShadowY-CBD(H83L/H86L) and Clover(T153M/F223R)-Cdc42 in mammalian cells as a negative control for FLIM imaging.

   Depositor

   Hideji Murakoshi

   Article

   Shibata et al Nat Commun. 2021 Feb 2;12(1):751. doi: 1

   Insert

   ShadowY-CBD(H83L/H86L)-P2A-Clover(T153M/F223R)-Cdc42
   

   Use

   Tags

   ShadowY, Clover(T153M/F223R)

   Expression

   Mammalian

   Mutation

   H83L/H86L: CDB(Cdc42 Binding Domain, Pak3, residu…

   Promoter

   CMV

   Available Since

   March 8, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. pGL3-pSMANTIS_1kb_KLF2mut 449,548,732,899,884 (All)

   Plasmid

   #194190

   Purpose

   Includes the promoter (1kb) of SMTS with 5 mutated KLF binding sites (positions 449,548,732,899,884)

   Depositor

   Matthias Leisegang, Ralf Brandes

   Article

   Leisegang et al Eur Heart J. 2019 Aug 7;40(30):2523-2533

   Insert

   SMANTIS promoter (1kb) (SMANTIS Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mutation

   5 mutated KLF binding sites (positions 449,548,73…

   Promoter

   SMANTIS promoter (1kb), mutated

   Available Since

   Jan. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pGL3-pSMANTIS_1kb_KLF2mut 899

    Plasmid

    #194193

    Purpose

    Includes the promoter (1kb) of SMTS with mutated KLF binding sites (position 899)

    Depositor

    Matthias Leisegang, Ralf Brandes

    Article

    Leisegang et al Eur Heart J. 2019 Aug 7;40(30):2523-2533

    Insert

    SMANTIS promoter (1kb) (SMANTIS Human)
    

    Use

    Luciferase

    Tags

    Expression

    Mutation

    mutated KLF binding sites (position 899)

    Promoter

    SMANTIS promoter (1kb), mutated

    Available Since

    Jan. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pCEP4-myc-S (B.1.351 lineage / South African variant)

    Plasmid

    #169849

    Purpose

    Mammalian expression plasmid for S of SARS-CoV-2 (B.1.351 lineage / South African variant) with N-terminal c-myc tag

    Depositor

    Erik Procko

    Article

    Zhang et al Nat Chem Biol. 2022 Mar;18(3):342-351. d

    Insert

    Protein S
    

    Use

    Tags

    HA leader and c-myc tag

    Expression

    Mammalian

    Mutation

    Codon-optimized for human cell expression.

    Promoter

    CMV

    Available Since

    Jan. 31, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. pTRE-SOX17-P2A-Venus-rpEF1a-Zeo

    Plasmid

    #169174

    Purpose

    piggyBac transposon to generate a Tet inducible SOX17 expressing cell line. Tet-On inducible when paired with #169175

    Depositor

    Igor Slukvin

    Article

    Jung et al Cell Rep. 2021 Feb 16;34(7):108758. doi:

    Insert

    SOX17-P2A-Venus (SOX17 Human, Synthetic)
    

    Use

    Piggybac transposon

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    pTREtight (tet-inducible promoter)

    Available Since

    Jan. 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. JA412

    Plasmid

    #49935

    Purpose

    Expresses a TALE-TET1CD (catalytic domain of TET1) fusion protein engineered to bind a site in the human KLF4 gene and demethylate CpGs adjacent to the binding site

    Depositor

    Keith Joung

    Article

    Maeder et al Nat Biotechnol. 2013 Oct 9. doi: 10.1038

    Insert

    Tet1CD KL-1 (KLF4 Human)
    

    Use

    TALEN

    Tags

    Expression

    Mutation

    Promoter

    EF1a

    Available Since

    Dec. 20, 2013

    Availability

    Academic Institutions and Nonprofits only

14. SL357

    Plasmid

    #49936

    Purpose

    Expresses a TALE-TET1FL (full length TET1) fusion protein engineered to bind a site in the human KLF4 gene and demethylate CpGs adjacent to the binding site

    Depositor

    Keith Joung

    Article

    Maeder et al Nat Biotechnol. 2013 Oct 9. doi: 10.1038

    Insert

    Tet1FL KL-1 (KLF4 Human)
    

    Use

    TALEN

    Tags

    Expression

    Mutation

    Promoter

    EF1a

    Available Since

    Dec. 20, 2013

    Availability

    Academic Institutions and Nonprofits only

15. pGL3-Enhancer-ZC3H12D_PromoterMUT

    Plasmid

    #153068

    Purpose

    ZC3H12D promoter region carrying mutations in BHLHE40 binding sites, cloned upstream of luciferase reporter

    Depositor

    Silvia Monticelli

    Article

    Emming et al Nat Immunol. 2020 Apr;21(4):388-399. doi

    Insert

    ZC3H12D promoter region mutated in BHLHE40 binding sites (ZC3H12D Human)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    Mutagenesis to disrupt 3 BHLHE40 binding sites. N…

    Promoter

    None

    Available Since

    Sept. 15, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. pBrain-GFP-TACC3KDP∆682-688-shTACC3

    Plasmid

    #69116

    Purpose

    Dual-promoter plasmid to express knockdown-proof human TACC3 (682-688aa ch-TOG binding site deleted) tagged with EGFP along with shRNA to knock down endogenous TACC3 in mammalian cells.

    Depositor

    Stephen Royle

    Article

    Gutierrez-Caballero et al Biol Open. 2015 Jan 16;4(2):170-9. doi:

    Inserts

    Transforming Acidic Coiled Coil protein 3 (TACC3 Human)
    shTACC3
    

    Use

    RNAi

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Deletion of amino acids 682-688 (region containin…

    Promoter

    CMV

    Available Since

    Oct. 6, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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17. JA431

    Plasmid

    #49937

    Purpose

    Expresses a TALE-TET1CD (catalytic domain of TET1) fusion protein engineered to bind a site in the human KLF4 gene and demethylate CpGs adjacent to the binding site

    Depositor

    Keith Joung

    Article

    Maeder et al Nat Biotechnol. 2013 Oct 9. doi: 10.1038

    Insert

    Tet1CD KL-2 (KLF4 Human)
    

    Use

    TALEN

    Tags

    Expression

    Mutation

    Promoter

    EF1a

    Available Since

    Dec. 10, 2013

    Availability

    Academic Institutions and Nonprofits only

18. pRetro-CAG-DsRedExpress-TVA

    Plasmid

    #235699

    Purpose

    Control plasmid expressing TVA and DsRed without G protein

    Depositor

    Guo-li Ming, Hongjun Song

    Article

    Sun et al Nature. 2025 Jan 16. doi: 10.1038/s41586

    Insert

    DsRedExpress, TVA800
    

    Use

    Retroviral

    Tags

    Expression

    Mutation

    Promoter

    CAG

    Available Since

    April 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. rag2:LRRC10_CE_pISceI

    Plasmid

    #223042

    Purpose

    Express LRRC10 gene in mesenchymal lineage of Zebrafish.

    Depositor

    Alejandro Gutierrez

    Article

    Ali et al Mol Cell. 2025 Mar 6;85(5):948-961.e11.

    Insert

    LRRC10 (LRRC10 Human)
    

    Use

    Express the insert(gene) in mesenchymal lineage o…

    Tags

    Expression

    Mutation

    Promoter

    Rag2

    Available Since

    Feb. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. rag2:BEST3_CE_pISceI

    Plasmid

    #223043

    Purpose

    Express BEST3 gene in mesenchymal lineage of Zebrafish.

    Depositor

    Alejandro Gutierrez

    Article

    Ali et al Mol Cell. 2025 Mar 6;85(5):948-961.e11.

    Insert

    BEST3 (BEST3 Human)
    

    Use

    Express the insert(gene) in mesenchymal lineage o…

    Tags

    Expression

    Mutation

    Promoter

    Rag2

    Available Since

    Feb. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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