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Pooled Library#51043PurposeSub-pool of Sabatini/Lander sgRNA library enriched for gene targets of unknown function.DepositorExpressionMammalianSpeciesHomo sapiensUseCRISPR and LentiviralAvailable sinceFeb. 7, 2014AvailabilityAcademic Institutions and Nonprofits only
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HUNK_pCSdest
Plasmid#53809DepositorInsertHUNK (HUNK Human)
UseTagsExpressionMammalianMutationPromoterSP6 and CMVAvailable sinceMarch 27, 2018AvailabilityIndustry, Academic Institutions, and Nonprofits -
CL20_mEGFP_UNK_B4GALNT2
Plasmid#205951PurposeExpress mEGFP-tagged fusion protein, UNK_B4GALNT2 from patient-derived sequenceDepositorUseTagsmEGFPExpressionMammalianMutationPromoterAvailable sinceNov. 9, 2023AvailabilityAcademic Institutions and Nonprofits only -
UNK_6xZNF_pGEX
Plasmid#215703PurposeRecombinant expression of UNK with dual-affinity tagDepositorInsertUNK (UNK Human)
UseTagsGST and SBPExpressionBacterialMutationPromoterAvailable sinceApril 12, 2024AvailabilityAcademic Institutions and Nonprofits only -
px458_2A_GFP_sgRNA_UNK_G1
Plasmid#127118DepositorInsertgRNA UNK (UNK Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceJuly 25, 2019AvailabilityAcademic Institutions and Nonprofits only -
pSkunk3-BLA
Plasmid#61531PurposePhagemid expressing streptomycin/spectinomycin resistance geneDepositorInsertaadA
UseTagsExpressionBacterialMutationPromoterlacIAvailable sinceDec. 12, 2014AvailabilityAcademic Institutions and Nonprofits only -
UNK_ZnF1-3_pGEX
Plasmid#219664PurposeRecombinant expression of UNK ZnF1-3 with dual-affinity tagDepositorInsertUnkempt Zinc Fingers 1-3
UseTagsGST and SBPExpressionBacterialMutationPromoterAvailable sinceJan. 10, 2025AvailabilityAcademic Institutions and Nonprofits only -
UNK_ZnF4-6_pGEX
Plasmid#219665PurposeRecombinant expression of UNK ZnF4-6 with dual-affinity tagDepositorInsertUnkempt Zinc Fingers 4-6
UseTagsGST and SBPExpressionBacterialMutationPromoterAvailable sinceJan. 10, 2025AvailabilityAcademic Institutions and Nonprofits only -
HUNK gRNA (BRDN0001148239)
Plasmid#75940Purpose3rd generation lentiviral gRNA plasmid targeting human HUNKDepositorInsertHUNK (HUNK Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
HUNK gRNA (BRDN0001146355)
Plasmid#75939Purpose3rd generation lentiviral gRNA plasmid targeting human HUNKDepositorInsertHUNK (HUNK Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
HUNK gRNA (BRDN0001145500)
Plasmid#75941Purpose3rd generation lentiviral gRNA plasmid targeting human HUNKDepositorInsertHUNK (HUNK Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
AAV pmSyn1-EBFP-Cre (AAV5)
Viral Prep#51507-AAV5PurposeReady-to-use AAV5 particles produced from AAV pmSyn1-EBFP-Cre (#51507). In addition to the viral particles, you will also receive purified AAV pmSyn1-EBFP-Cre plasmid DNA. EBFP-Cre expression under a human synapsin1 promoter. These AAV preparations are suitable purity for injection into animals.DepositorPromoterpmSyn1TagsEBFPAvailable sinceOct. 30, 2017AvailabilityAcademic Institutions and Nonprofits only -
AAV phSyn1(S)-DreO-bGHpA (AAV Retrograde)
Viral Prep#50363-AAVrgPurposeReady-to-use AAV Retrograde particles produced from AAV phSyn1(S)-DreO-bGHpA (#50363). In addition to the viral particles, you will also receive purified AAV phSyn1(S)-DreO-bGHpA plasmid DNA. hSyn-driven Dre recombinase expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.DepositorPromoterSynTagsNoneAvailable sinceAug. 18, 2020AvailabilityAcademic Institutions and Nonprofits only -
AAV phSyn1(S)-DreO-bGHpA (AAV5)
Viral Prep#50363-AAV5PurposeReady-to-use AAV5 particles produced from AAV phSyn1(S)-DreO-bGHpA (#50363). In addition to the viral particles, you will also receive purified AAV phSyn1(S)-DreO-bGHpA plasmid DNA. hSyn-driven Dre recombinase expression. These AAV preparations are suitable purity for injection into animals.DepositorPromoterSynTagsNoneAvailable sinceMay 29, 2019AvailabilityAcademic Institutions and Nonprofits only -
AAV pTRE-FSF-FLEX-EGFP-WPRE-bGHpA (AAV1)
Viral Prep#65453-AAV1PurposeReady-to-use AAV1 particles produced from AAV pTRE-FSF-FLEX-EGFP-WPRE-bGHpA (#65453). In addition to the viral particles, you will also receive purified AAV pTRE-FSF-FLEX-EGFP-WPRE-bGHpA plasmid DNA. TRE-driven, Cre and Flp-dependent expression of EGFP. These AAV preparations are suitable purity for injection into animals.DepositorPromotertetOTagsEGFP (Cre and Flp-dependent)Available sinceFeb. 14, 2022AvailabilityAcademic Institutions and Nonprofits only -
AAV phSyn1(S)-FlpO-bGHpA (AAV Retrograde)
Viral Prep#51669-AAVrgPurposeReady-to-use AAV Retrograde particles produced from AAV phSyn1(S)-FlpO-bGHpA (#51669). In addition to the viral particles, you will also receive purified AAV phSyn1(S)-FlpO-bGHpA plasmid DNA. hSyn-driven FlpO expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.DepositorPromoterSynTagsNoneAvailable sinceOct. 28, 2021AvailabilityAcademic Institutions and Nonprofits only -
Syn61
Bacterial Strain#174513PurposeRecoded E. coli strain without TCG, TCA, or TAG codons in all open reading frames. Full sequence - GenBank: CP040347.1DepositorBacterial ResistanceStreptomycinAvailable sinceNov. 18, 2021AvailabilityAcademic Institutions and Nonprofits only -
HR700_TP53Exon5mut
Pooled Library#229137PurposeDonor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.DepositorExpressionMammalianSpeciesHomo sapiensUseCRISPR and Cre/LoxAvailable sinceFeb. 24, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits -
HR700_TP53Exon6mut
Pooled Library#229138PurposeDonor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.DepositorExpressionMammalianSpeciesHomo sapiensUseCRISPR and Cre/LoxAvailable sinceFeb. 24, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits -
HR700_TP53Exon7mut
Pooled Library#229139PurposeDonor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.DepositorExpressionMammalianSpeciesHomo sapiensUseCRISPR and Cre/LoxAvailable sinceFeb. 24, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits