We narrowed to 198 results for: mecp2
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Plasmid#163705PurposepAAV plasmid to induce expression of universal negative control micro-RNA and EGFPDepositorInsertmirNega and EGFP
UseAAVPromoterCAGAvailable sinceMarch 17, 2021AvailabilityAcademic Institutions and Nonprofits only -
pLenti-CaMaKIIalpha-mKO2
Plasmid#86156PurposeLentiviral fluorescent reporter using the neuronal cell type-specific promoter of the CaM Kinase II alpha gene.DepositorInsertmKO2
UseLentiviralAvailable sinceMarch 15, 2017AvailabilityAcademic Institutions and Nonprofits only -
FUW-crRNA-scrambled-U6_TRE-dLbCpf1-NLS-hCTCF_WT-HA-P2A-tagBFP
Plasmid#194897PurposeDox-inducible all-in-one lentiviral construct to express dCpf1-CTCF-WT and scrambled crRNA without target in human genome.DepositorInsertsdLbCpf1-NLS-hCTCF_WT
U6-crRNA-scramble
UseLentiviralTagsHAExpressionMammalianMutationHuman codon optimized catalytically inactive LbCp…PromoterTRE and U6Available sinceJan. 25, 2023AvailabilityAcademic Institutions and Nonprofits only -
pSt1374-N-NLS-DNMT3L-L-DNMT3Amut-L-dcas9-NLS
Plasmid#112209PurposeTargeted DNA methylationDepositorHas service50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNAUseCRISPRMutationD10A,H840A,N863A,C710SAvailable sinceOct. 30, 2020AvailabilityAcademic Institutions and Nonprofits only -
pSt1374m-EF1alpha-N-NLS-DNMT3L-L-DNMT3Amut-L-dcas9-NLS
Plasmid#112215PurposeTargeted DNA methylationDepositorHas service50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNAUseCRISPRTagsmCherryMutationD10A,H840A,N863A,C710SAvailable sinceAug. 2, 2018AvailabilityAcademic Institutions and Nonprofits only -
pLV_hPGK-2xMeCP2NLS-dCas9-HA-2xSV40NLS-ZIM3-NpNLS-P2A/T2A-mTagBFP2-2xMycNLS-WPRE
Plasmid#254800PurposeConstituitve expression of dCas9-ZIM3 with optimized nuclear localization in iPSC-derived neurons via lenti deliveryDepositorInsert2xMeCP2NLS-dCas9-HA-2xSV40NLS-ZIM3-NpNLS-P2A/T2A-mTagBFP2-2xMycNLS
UseCRISPR and LentiviralExpressionMammalianMutationcatalytically dead spCas9PromoterhPGKAvailable sinceAug. 31, 2026AvailabilityAcademic Institutions and Nonprofits only -
pLV_hPGK-2xMeCP2NLS-Cas9-HA-2xSV40NLS-NpNLS-P2A/T2A-mTagBFP2-2xMycNLS-WPRE
Plasmid#254801PurposeConstituitve expression of spCas9 with optimized nuclear localization in iPSC-derived neurons via lenti deliveryDepositorInsert2xMeCP2NLS-Cas9-HA-2xSV40NLS-NpNLS-P2A/T2A-mTagBFP2-2xMycNLS
UseCRISPR and LentiviralExpressionMammalianPromoterhPGKAvailable sinceAug. 31, 2026AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-NLS-DNMT3A-L-N-spC9-N-intein-hGH
Plasmid#112212PurposeTargeted DNA methylationDepositorAvailable sinceOct. 30, 2020AvailabilityAcademic Institutions and Nonprofits only -
pLV_hPGK-2xMeCP2NLS-dCas9-HA-2xSV40NLS-KOX1-NpNLS-P2A/T2A-mTagBFP2-2xMycNLS-WPRE
Plasmid#254799PurposeConstituitve expression of dCas9-KOX1 with optimized nuclear localization in iPSC-derived neurons via lenti deliveryDepositorInsert2xMeCP2NLS-dCas9-HA-2xSV40NLS-KOX1-NpNLS-P2A/T2A-mTagBFP2-2xMycNLS
UseCRISPR and LentiviralExpressionMammalianMutationcatalytically dead spCas9PromoterhPGKAvailable sinceAug. 31, 2026AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-C-intein-C-spC9-H840A-N863A-2xNLS-hGH
Plasmid#112211PurposeTargeted DNA methylationDepositorInsertC-terminus of dCas9
UseAAVMutationD10AAvailable sinceOct. 30, 2020AvailabilityAcademic Institutions and Nonprofits only -
human SLC12A5-V5-HA-2A-Luciferase repair template
Plasmid#158576PurposeFor targeted insertion of V5-HA-2A-Luciferase reporter before the stop codon of the human SLC12A5 gene that encodes neuronal chloride transporter KCC2 protein.DepositorHas service50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNAInserthuman SLC12A5 5' homology arm-V5-HA-2A-Luciferase-3' homology arm (SLC12A5 Human)
TagsV5 and HA on the endogenous KCC2 protein productExpressionMammalianAvailable sinceSept. 29, 2020AvailabilityAcademic Institutions and Nonprofits only -
pAAV-5U6-sgRNAs-hsyn-EGFP
Plasmid#112213PurposeTargeted DNA methylationDepositorInsertsgRNAs
UseAAVAvailable sinceOct. 30, 2020AvailabilityAcademic Institutions and Nonprofits only -
sgRNA targeting human SLC12A5 gene stop codon
Plasmid#158577PurposeFor generate double-strand DNA break near the stop codon of the human SLC12A5 gene that encodes neuronal chloride transporter KCC2 protein.DepositorInsertsgRNA targeting human SLC12A5 gene stop codon
UseCRISPRTagsCas9 and GFPExpressionMammalianAvailable sinceSept. 29, 2020AvailabilityAcademic Institutions and Nonprofits only -
pXPR_051_dCas9-KRAB-HA
Plasmid#228936PurposeAll-in-one dCas9-KRAB-MeCP2 plasmid for cloning of custom sgRNADepositorTypeEmpty backboneUseCRISPR and LentiviralExpressionMammalianAvailable sinceApril 9, 2025AvailabilityAcademic Institutions and Nonprofits only -
pXPR_BRD051d_sgCiPELO #2
Plasmid#229018PurposeExpression of CRISPRi PELO sgRNA #2DepositorAvailable sinceMarch 20, 2025AvailabilityAcademic Institutions and Nonprofits only -
pBK2043-AAV-2xSp1-2xNFkB-EFSNC-dSaCas9
Plasmid#223163Purpose2nd gen. AAV backbone for dSaCas9 (endonuclease dead Cas9 from Staphylococcus aureus) and Sa-gRNA ScaffoldDepositorTypeEmpty backboneUseAAV and CRISPRTags3xFLAGExpressionMammalianMutationEncodes aa 204-310 (MECP2)Available sinceAug. 22, 2024AvailabilityAcademic Institutions and Nonprofits only -
pTYB1-MBD2-MBDTRD pc4791
Plasmid#229754PurposeBacterial expression vector of MBD2-MBDTRD domains (aa 153-235) C-terminal tagged to the intein.DepositorInsertMBD2 (Mbd2 Mouse)
TagsInteinExpressionBacterialMutationMBD2-MBDTRD domains (aa 153-235)PromoterT7Available sinceOct. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
dCas9-RPT6-FLAG
Plasmid#205416PurposeExpresses dCas9-RPT6 with FLAG labelDepositorAvailable sinceDec. 1, 2023AvailabilityAcademic Institutions and Nonprofits only