We narrowed to 2,556 results for: neurod

1. hnRNPA1_allW_D262V-FLAG-IRES-eGFP

   Plasmid

   #234621

   Purpose

   Mammalian expression of full-length hnRNPA1 D262V with all aromatic amino acids in the C-terminal LCD mutated to W keeping the hexapeptide fibril core (SYNDFG) and the PY-NLS intact.

   Depositor

   Tanja Mittag

   Article

   Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2

   Insert

   hnRNPA1 allW D262V (HNRNPA1 Human)
   

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Famillial ALS mutation D262V, all aromatic amino …

   Promoter

   CMV

   Available Since

   March 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pET28.His.3C.86b.8D2Q.Tau2N4R

   Plasmid

   #226400

   Purpose

   Expresses his-tagged, 3C-cleavable, 86b (split luciferase fragment)-tagged 8D2Q mutant 2N4R tau for recombinant protein production in bacteria

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau (MAPT Human, synthetic)
   

   Tags

   His.3C.86b

   Expression

   Bacterial

   Mutation

   8D2Q.Tau2N4R

   Available Since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pET28.His.3C.86b.20D3Q.Tau2N4R

   Plasmid

   #226401

   Purpose

   Expresses his-tagged, 3C-cleavable, 86b (split luciferase fragment)-tagged 20D3Q mutant 2N4R tau for recombinant protein production in bacteria

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Tags

   His.3C.86b

   Expression

   Bacterial

   Mutation

   20D3Q, Tau2N4R

   Available Since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. TH0994-pOCC177-Fus-wt_(1-211)

   Plasmid

   #221886

   Purpose

   Shuttle vector for baculovirus production, using FlashBac bacmid

   Depositor

   Anthony Hyman

   Article

   Wang et al Cell. 2018 Jul 26;174(3):688-699.e16. do

   Insert

   FUS (FUS Human)
   

   Tags

   6xHis-MBP-PreScission and TEV-SNAP-tag

   Expression

   Insect

   Mutation

   PLD domain (aa 1-211)

   Promoter

   PH promoter

   Available Since

   July 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. TH1148-pOCC177-FUS(Nhe)-PLD_YtoF

   Plasmid

   #221887

   Purpose

   Shuttle vector for baculovirus production, using FlashBac bacmid

   Depositor

   Anthony Hyman

   Article

   Wang et al Cell. 2018 Jul 26;174(3):688-699.e16. do

   Insert

   FUS (FUS Human)
   

   Tags

   6xHis-MBP-PreScission and TEV-SNAP-tag

   Expression

   Insect

   Mutation

   In PLD all Tyr (Y) changed to Phe (F)

   Promoter

   PH promoter

   Available Since

   July 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. TH1149-pOCC177-FUS(Nhe)-RGG_RtoK

   Plasmid

   #221888

   Purpose

   Shuttle vector for baculovirus production, using FlashBac bacmid

   Depositor

   Anthony Hyman

   Article

   Wang et al Cell. 2018 Jul 26;174(3):688-699.e16. do

   Insert

   FUS (FUS Human)
   

   Tags

   6xHis-MBP-PreScission and TEV-SNAP-tag

   Expression

   Insect

   Mutation

   In RGG (aa 212-526) most of Arg (R) changed to Ly…

   Promoter

   PH promoter

   Available Since

   July 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. FUW-hSNCA(D2R)-NE

   Plasmid

   #215487

   Purpose

   Lentiviral expression of mutated alpha-synuclein (2nd amino acid aspartate mutated to arginine) in mammalian cells

   Depositor

   Ophir Shalem

   Article

   Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

   Insert

   alpha-synuclein (SNCA Human)
   

   Use

   Lentiviral

   Tags

   NE tag

   Expression

   Mammalian

   Mutation

   D (second aa) mutated to R

   Promoter

   Ubc

   Available Since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. FUW-hSNCA(D2E)-NE

   Plasmid

   #215488

   Purpose

   Lentiviral expression of mutated alpha-synuclein (2nd amino acid aspartate mutated to glutamate) in mammalian cells

   Depositor

   Ophir Shalem

   Article

   Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

   Insert

   alpha-synuclein (SNCA Human)
   

   Use

   Lentiviral

   Tags

   NE tag

   Expression

   Mammalian

   Mutation

   D (second aa) mutated to E

   Promoter

   Ubc

   Available Since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. FUW-hSNCA(D2R)-GFP

   Plasmid

   #215490

   Purpose

   Lentiviral expression and easy visualization of mutated alpha-synuclein (2nd amino acid aspartate mutated to arginine) in mammalian cells

   Depositor

   Ophir Shalem

   Article

   Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

   Insert

   alpha-synuclein (SNCA Human)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   D (second aa) mutated to R

   Promoter

   Ubc

   Available Since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. FUW-hSNCA(D2E)-GFP

    Plasmid

    #215491

    Purpose

    Lentiviral expression and easy visualization of mutated alpha-synuclein (2nd amino acid aspartate mutated to glutamate) in mammalian cells

    Depositor

    Ophir Shalem

    Article

    Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

    Insert

    alpha-synuclein (SNCA Human)
    

    Use

    Lentiviral

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    D (second aa) mutated to E

    Promoter

    Ubc

    Available Since

    April 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. Kv1.1 K+ channel scFv [K20/78]

    Plasmid

    #182065

    Purpose

    Mammalian Expression of Kv1.1 K+ channel scFv. Derived from hybridoma K20/78.

    Depositor

    James Trimmer

    Article

    Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

    Insert

    recombinant mouse scFv targeting Kv1.1 K+ channel (Rattus norvegicus) (Kcna1 Mouse)
    

    Tags

    Sortase, His

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. Anti-Kv3.3 K+ channel [N375/67R]

    Plasmid

    #182113

    Purpose

    Mammalian Expression Plasmid of anti-Kv3.3 K+ channel (Mouse). Derived from hybridoma N375/67.

    Depositor

    James Trimmer

    Article

    Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

    Insert

    anti-Kv3.3 K+ channel (Mus musculus) recombinant mouse monoclonal antibody (Kcnc3 Mouse)
    

    Expression

    Mammalian

    Promoter

    Dual CMV

    Available Since

    Feb. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. Lenti-sgRNA-Cre-GpNLuc-sgmATM

    Plasmid

    #208392

    Purpose

    Lentiviral vector expressing Cas9, GpNLuc, and sgRNA targeting murine ATM gene.

    Depositor

    Gaorav Gupta

    Article

    Cho et al Nature. 2024 Jan 10. doi: 10.1038/s41586

    Insert

    sgATM (Atm Mouse)
    

    Use

    Lentiviral and Luciferase

    Expression

    Mammalian

    Mutation

    WT

    Available Since

    Jan. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV2ss-EFS-GFP-synPolyA-U6-sgHTT1-U6-sgCas9

    Plasmid

    #190903

    Purpose

    AAV-KamiCas9 vector expressing expressing thew GFP reporter gene and sgHTT and sgCas9

    Depositor

    Nicole Déglon

    Article

    Duarte et al Mol Ther Methods Clin Dev. 2023 Mar 27;2

    Insert

    GFP, sgHTT and sgCas9 (HTT Human)
    

    Use

    AAV and CRISPR

    Promoter

    EFS and U6

    Available Since

    March 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pD649-HAsp-ERBB4-COMP5AP-AviTag-9xHis

    Plasmid

    #157495

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    ERBB4 (ERBB4 Human)
    

    Tags

    COMP5AP-AviTag-9xHis

    Expression

    Mammalian

    Promoter

    CMV/SP6

    Available Since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. Kv1.1 K+ channel scFv [K20/78]

    Plasmid

    #190486

    Purpose

    Mammalian Expression of Kv1.1 K+ channel scFV. Derived from hybridoma K20/78.

    Depositor

    James Trimmer

    Article

    Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

    Insert

    Kv1.1 K+ channel (Rattus norvegicus) recombinant scFV (Kcna1 Mouse)
    

    Tags

    HA, Sortase, 6xHis

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Nov. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. Kv3.3 K+ channel scFv [N375/67]

    Plasmid

    #190549

    Purpose

    Mammalian Expression of Kv3.3 K+ channel scFV. Derived from hybridoma N375/67.

    Depositor

    James Trimmer

    Article

    Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

    Insert

    Kv3.3 K+ channel (Mus musculus) recombinant scFV (Kcnc3 Mouse)
    

    Tags

    HA, Sortase, 6xHis

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Nov. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Anti-Kv3.3 K+ channel [N375/67R]

    Plasmid

    #177537

    Purpose

    Mammalian Expression Plasmid of anti-Kv3.3 K+ channel (Mouse). Derived from hybridoma N375/67.

    Depositor

    James Trimmer

    Article

    Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

    Insert

    anti-Kv3.3 K+ channel (Mus musculus) recombinant mouse monoclonal antibody (Kcnc3 Mouse)
    

    Expression

    Mammalian

    Promoter

    Dual CMV

    Available Since

    May 17, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. A1-LCD-30G+30S-12F+12Y

    Plasmid

    #178687

    Purpose

    Bacterial expression of N-terminally 6His tagged A1-LCD with thirty Gly residues replaced with Ser, twelve Phe residues replaced with Tyr (LCD: low-complexity domain, aa 186-320)

    Depositor

    Tanja Mittag

    Article

    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1

    Insert

    A1-LCD-30G+30S-12F+12Y (HNRNPA1 Human)
    

    Tags

    6xHis

    Expression

    Bacterial

    Mutation

    thirty Gly residues replaced with Ser, twelve Phe…

    Available Since

    March 17, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. A1-LCD-30G+30S+7F-7Y

    Plasmid

    #178686

    Purpose

    Bacterial expression of N-terminally 6His tagged A1-LCD with thirty Gly residues replaced with Ser, seven Tyr residues replaced with Phe (LCD: low-complexity domain, aa 186-320)

    Depositor

    Tanja Mittag

    Article

    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1

    Insert

    A1-LCD-30G+30S+7F-7Y (HNRNPA1 Human)
    

    Tags

    6xHis

    Expression

    Bacterial

    Mutation

    thirty Gly residues replaced with Ser, seven Tyr …

    Available Since

    March 17, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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