We narrowed to 418 results for: px458

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pX458_miR-290-295KO-gRNA2

Plasmid

#172710

Purpose

Cas9 with 3' gRNA for paired CRISPR KO of miR-290-295 cluster

Depositor

Constance Ciaudo

Publication

Schaefer et al EMBO Rep. 2022 Jul 28:e54762. doi: 10.15

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

miR-290-295

Use

CRISPR

Available since

Aug. 15, 2022

Availability

Academic Institutions and Nonprofits only

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pX458- PSMF1 guide 1

Plasmid

#251203

Purpose

Transient transfection-compatible vector driving expression of spCas9 and production of sgRNA targeting exon2 of PSMF1

Depositor

Wade Harper

Publication

Adolf et al bioRxiv 2026.05.28.728263

Insert

PSMF1 guide 1

Use

CRISPR

Expression

Mammalian

Available since

June 2, 2026

Availability

Academic Institutions and Nonprofits only

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pX458- PSMF1 guide 2

Plasmid

#251204

Purpose

Transient transfection-compatible vector driving expression of spCas9 and production of sgRNA targeting exon2 of PSMF1

Depositor

Wade Harper

Publication

Adolf et al bioRxiv 2026.05.28.728263

Insert

PSMF1 guide 2

Use

CRISPR

Expression

Mammalian

Available since

June 2, 2026

Availability

Academic Institutions and Nonprofits only

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PX458 BLTP3A knockout

Plasmid

#241256

Purpose

Knock-out plasmid targeting the second exon of human BLTP3A (UHRF1BP1)

Depositor

Pietro De Camilli

Publication

Hanna et al EMBO J (2025) 44: 6168 - 6195

Insert

BLTP3A (UHRF1BP1) KO gRNA (BLTP3A Human)

Expression

Mammalian

Available since

Nov. 11, 2025

Availability

Academic Institutions and Nonprofits only

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pX458-ARHGEF7/B-Pix

Plasmid

#241368

Purpose

Mammalian expression of SpCas9 and gRNA targeting ARHGEF7 (β-Pix)

Depositor

Gaudenz Danuser

Publication

Weiss et al Sci Signal. 2025 May 20;18(887):eadk0922

Insert

ARHGEF7 gRNA (ARHGEF7 Human)

Expression

Mammalian

Promoter

U6

Available since

Aug. 27, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-HP1a-gRNA-2

Plasmid

#237635

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

Depositor

Denes Hnisz

Publication

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HP1a gRNA (CBX5 Human)

Use

CRISPR

Tags

mCherry

Available since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-HP1a-gRNA-1

Plasmid

#237634

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

Depositor

Denes Hnisz

Publication

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

HP1a gRNA (CBX5 Human)

Use

CRISPR

Tags

mCherry

Available since

May 6, 2025

Availability

Academic Institutions and Nonprofits only

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PX458-eBFP2-sgRNA_CTCF_ZF1

Plasmid

#233090

Purpose

Expression vector for a sgRNA against the mouse CTCF ZF1 region and SpCas9-T2A-eBFP2.

Depositor

Danny Reinberg

Publication

Lucero et al bioRxiv, March 19, 2025

Insert

spCas9-T2A-eBFP2 (Ctcf )

Expression

Mammalian

Available since

March 26, 2025

Availability

Academic Institutions and Nonprofits only

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PX458-3xHA-dFnCas9

Plasmid

#201954

Purpose

Mammalian expression plasmid of dead FnCas9 with T2A-EGFP and cloning backbone for sgRNA

Depositor

Debojyoti Chakraborty

Publication

Acharya et al Nat Commun. 2024 Jun 28;15(1):5471. doi:

Insert

3xHA-NLS-dFnCas9-T2A-EGFP

Use

CRISPR

Tags

3xHA, NLS, and T2A-EGFP

Expression

Mammalian

Mutation

D11A and H969A on FnCas9

Promoter

Cbh

Available since

May 7, 2024

Availability

Academic Institutions and Nonprofits only

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PX458-3xHA-FnCas9ABEmax8.17d

Plasmid

#201955

Purpose

Mammalian expression plasmid of FnCas9ABEmax8.17d base editor with T2A-EGFP and cloning backbone for sgRNA

Depositor

Debojyoti Chakraborty

Publication

Acharya et al Nat Commun. 2024 Jun 28;15(1):5471. doi:

Insert

bpNLS-FnCas9ABEmax8.17d-bpNLS-3xHA-T2A-EGFP

Use

CRISPR

Tags

3xHA, NLS, and T2A-EGFP

Expression

Mammalian

Mutation

D11A on FnCas9, V82S, V106W, Q154R on mutant TadA

Promoter

Cbh

Available since

May 7, 2024

Availability

Academic Institutions and Nonprofits only

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pX458-tRNA-SpCas9

Plasmid

#195183

Purpose

Vector for transient Cas9 and EGFP expression. Small tRNA promoter for sgRNA cloning by GoldenGate.

Depositor

Stephanie Roessler

Insert

Cas9

Use

CRISPR

Promoter

tRNA-Gln

Available since

Feb. 21, 2024

Availability

Academic Institutions and Nonprofits only

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hLig4 guide2 in pX458

Plasmid

#211536

Purpose

sgRNA-2 against Lig4

Depositor

Agnel Sfeir

Publication

Brambati et al Science. 2023 Aug 11;381(6658):653-660.

Insert

sgRNA hLig4 (LIG4 Synthetic)

Use

CRISPR

Expression

Mammalian

Promoter

u6

Available since

Jan. 22, 2024

Availability

Academic Institutions and Nonprofits only

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hLig4 guide1 in pX458

Plasmid

#211535

Purpose

sgRNA-1 against Lig4

Depositor

Agnel Sfeir

Publication

Brambati et al Science. 2023 Aug 11;381(6658):653-660.

Insert

sgRNA hLig4 (LIG4 Synthetic)

Use

CRISPR

Expression

Mammalian

Promoter

u6

Available since

Jan. 22, 2024

Availability

Academic Institutions and Nonprofits only

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Px458-Cas9n-Trp73-Exon4-3sgRNA

Plasmid

#88850

Purpose

CRISPR KO of Trp73

Depositor

Joan Massague

Publication

Wang et al Cell Stem Cell. 2017 Jan 5;20(1):70-86.

Insert

Trp73 (Trp73 Mouse)

Use

CRISPR

Expression

Mammalian

Available since

July 11, 2017

Availability

Academic Institutions and Nonprofits only
Px458-Cas9n-Trp73-Exon4-4sgRNA

Plasmid

#88851

Purpose

CRISPR KO of Trp73

Depositor

Joan Massague

Publication

Wang et al Cell Stem Cell. 2017 Jan 5;20(1):70-86.

Insert

Trp73 (Trp73 Mouse)

Use

CRISPR

Expression

Mammalian

Available since

July 11, 2017

Availability

Academic Institutions and Nonprofits only
Helios-CRISPR #1 (PX458-EF1a-pSpCas9(BB)-2A-GFP)

Plasmid

#75244

Purpose

CRISPR/Cas9 plasmid against human Helios

Depositor

Ria Baumgrass

Publication

Gabriel et al J Biol Chem. 2016 Sep 16. pii: jbc.M116.

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

sgRNA against human Helios (IKZF2 Human)

Use

CRISPR

Available since

June 9, 2016

Availability

Academic Institutions and Nonprofits only

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pX458_mCherry-NPM1-gRNA for HCT116

Plasmid

#238249

Purpose

Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to NPM1 locus

Depositor

Denes Hnisz

Publication

Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

Insert

NPM1

Use

CRISPR

Available since

June 3, 2025

Availability

Academic Institutions and Nonprofits only

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pX458_miR-290-295KO-gRNA3

Plasmid

#172711

Purpose

Cas9 with 5' gRNA for paired CRISPR KO of miR-290-295 cluster

Depositor

Constance Ciaudo

Publication

Schaefer et al EMBO Rep. 2022 Jul 28:e54762. doi: 10.15

Insert

miR-290-295

Use

CRISPR

Available since

Aug. 15, 2022

Availability

Academic Institutions and Nonprofits only

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pX458-MMETn-del-gRNA2

Plasmid

#185007

Purpose

expression of gRNA and Cas9 from S. pyogenes with 2A-EGFP

Depositor

Denes Hnisz

Publication

Asimi et al Nat Genet. 2022 Aug;54(8):1238-1247. doi

Insert

MMETn-del-gRNA2

Use

CRISPR

Available since

June 17, 2022

Availability

Academic Institutions and Nonprofits only

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pX458-IAP-del-gRNA1

Plasmid

#185002

Purpose

expression of gRNA and Cas9 from S. pyogenes with 2A-EGFP

Depositor

Denes Hnisz

Publication

Asimi et al Nat Genet. 2022 Aug;54(8):1238-1247. doi

Insert

IAP-del-gRNA1 (Akp3 Mouse)

Use

CRISPR

Available since

June 17, 2022

Availability

Academic Institutions and Nonprofits only

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