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pAAV-hST3GAL6-RFP

Plasmid

#22923

Depositor

Edward Callaway

Publication

Nathanson et al Front Neural Circuits. 2009 Nov 9;3:19.

Insert

human type 2 lactosamine alpha-2,3-sialyltransferase promoter driving DsRedExpress (ST3GAL6 Human)

Use

AAV

Expression

Mammalian

Available since

May 25, 2010

Availability

Academic Institutions and Nonprofits only

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pAAV/hSyn-SCLM

Plasmid

#216760

Purpose

AAV2 transfer vector with the human synapsin I promoter for neuronal expression of SuperClomeleon

Depositor

George Augustine

Insert

SuperClomeleon

Use

AAV

Expression

Mammalian

Mutation

S30R and 11 AA deletion in the Cerulean CFP moiet…

Promoter

hSyn (human synapsin I)

Available since

April 10, 2024

Availability

Academic Institutions and Nonprofits only

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AiP13318 - pAAV-AiE0390m_3xC2-minBG-SYFP2-4x2C-WPRE3-BGHpA (Alias: CN3318)

Plasmid

#208167

Purpose

AiE0390m_3xC2 is an optimized enhancer sequence designed to drive AAV-mediated transgene expression in brain astrocytes

Depositor

Allen Institute for Brain Science, Jonathan Ting

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available since

Oct. 23, 2023

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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AAV_Syn_Xph20_eGFP_CCR5TC

Plasmid

#187444

Purpose

Encodes a specific PSD-95 binder (Xph20) fused to eGFP, CCR5 left-handed zinc finger, and KRAB(A) transcriptional repressor domain

Depositor

Matthieu Sainlos

Publication

Rimbault et al Elife. 2024 Jan 3;13:e69620. doi: 10.755

Insert

Xph20

Use

AAV

Tags

eGFP

Expression

Mammalian

Promoter

Synapsin

Available since

Aug. 23, 2022

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pAAV_GWRev_Dest

Plasmid

#86954

Purpose

Gateway destination transfer plasmid for making AAV. Contains a DIO cassette for cre-induction. With cre, insert will flip backwards, causing it to turn off (cre-off)

Depositor

Joseph Dougherty

Publication

Cammack et al Proc Natl Acad Sci U S A. 2020 May 5;117

Type

Empty backbone

Use

AAV

Expression

Mammalian

Available since

April 13, 2020

Availability

Academic Institutions and Nonprofits only

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pAAV-G12-mTGFB1

Plasmid

#219553

Purpose

mTGFB1 expression in mammlian cells. pAAV vector. Reporter plasmid.

Depositor

Vladislav Verkhusha

Publication

Baloban et al Protein Sci. 2024 May;33(5):e4993. doi:

Insert

mTGFB1 (Tgfb1 Mouse)

Use

AAV

Expression

Mammalian

Promoter

12xUAS with TATA-box minimal promoter

Available since

May 23, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-Hyg-FHIT

Plasmid

#16410

Depositor

Bert Vogelstein

Publication

Kohli et al Nucleic Acids Res. 2004 . 32(1):e3.

Insert

FHIT Hyg targeting (FHIT Human)

Use

AAV; Adeno-associated viral

Expression

Mammalian

Available since

April 24, 2008

Availability

Academic Institutions and Nonprofits only
pAAV-Neo-PTEN

Plasmid

#16411

Depositor

Bert Vogelstein

Publication

Kohli et al Nucleic Acids Res. 2004 . 32(1):e3.

Insert

PTEN Neo targeting (PTEN Human)

Use

AAV; Adeno-associated viral

Expression

Mammalian

Available since

April 7, 2008

Availability

Academic Institutions and Nonprofits only
pAAV-CAG-eGFP-T7

Plasmid

#242778

Purpose

AAV transfer plasmid expressing eGFP-T7 under a CAG promoter.

Depositor

Andrew Payne

Publication

Park et al bioRxiv 2025.09.26.678648

Insert

EGFP

Use

AAV

Tags

T7

Promoter

CAG

Available since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-short Cre-on G/W

Plasmid

#86949

Purpose

Gateway destination transfer plasmid for making AAV. Contains a DIO cassette for cre-induction. For introducing large constructs into AAV

Depositor

Joseph Dougherty, Rob Mitra

Publication

Cammack et al Proc Natl Acad Sci U S A. 2020 May 5;117

Type

Empty backbone

Use

AAV

Expression

Mammalian

Available since

April 13, 2020

Availability

Academic Institutions and Nonprofits only

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AAV_Dbh HMEJ donor

Plasmid

#97320

Purpose

HMEJ donor for fusing a p2A-mCherry-WPRE reporter to mouse Dbh. AAV backbone.

Depositor

Hui Yang

Publication

Yao et al Cell Res. 2017 May 19. doi: 10.1038/cr.2

Insert

Dbh HMEJ donor

Use

AAV and Mouse Targeting

Expression

Mammalian

Available since

July 13, 2017

Availability

Academic Institutions and Nonprofits only

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aav-SYN-FLEX-tdNfsB(F124W)-mCherry (eNTR)

Plasmid

#113763

Purpose

AAV-mediated conditional expression of bacterial tdNfsB-mCherry (eNTR) under the SYN promoter

Depositor

Luke Lavis

Publication

Gruber et al ACS Chem Biol. 2018 Aug 29. doi: 10.1021

Insert

tdNfsB(F124W)-mCherry

Use

AAV and Cre/Lox

Tags

mCherry

Expression

Mammalian

Mutation

F124W

Promoter

Synapsin

Available since

Sept. 17, 2018

Availability

Academic Institutions and Nonprofits only

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AAV-FLEX-EGFP-mir30(Scn9a-scrambled)

Plasmid

#79671

Purpose

Scrambled control for Cre-dependent knockdown of Scn9a (Nav1.7)

Depositor

Scott Sternson

Publication

Branco et al Cell. 2016 Jun 16;165(7):1749-61. doi: 1

Insert

EGFP

Use

AAV and Cre/Lox

Expression

Mammalian

Promoter

CAG

Available since

Sept. 13, 2018

Availability

Academic Institutions and Nonprofits only

Cited by

2 Articles

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AAV1 for Split-PE, SpCas9 nickase (PKC1001)

Plasmid

#190111

Purpose

AAV1 for expression of nickase SpCas9(H840A) for Split-PE use

Depositor

Keith Joung

Publication

Grunewald et al Nat Biotechnol. 2023 Mar;41(3):337-343.

Insert

nSpCas9

Use

AAV

Tags

bpNLS

Mutation

H840A

Promoter

EF1a

Available since

Sept. 26, 2022

Availability

Academic Institutions and Nonprofits only

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pAAV_EF1a_DIO_HA/FLAG_muMASS_LF

Plasmid

#213394

Purpose

Loss of function variant of uMASS_1 opioid sensor. AAV virus production for Cre dependent expression.

Depositor

Andre Berndt

Publication

Rappleye et al ACS Sens. 2023 Nov 24;8(11):4233-4244. d

Insert

uMASS_LF

Use

AAV and Cre/Lox

Expression

Mammalian

Available since

Feb. 13, 2024

Availability

Academic Institutions and Nonprofits only

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AAV.CBA.YFP.miR-E_shStk16-1

Plasmid

#180391

Purpose

Producing AAV that encodes mouse Stk16 shRNA-1 with miR-E backbone

Depositor

Huda Zoghbi

Publication

Lee et al J Clin Invest. 2022 May 2;132(9). pii: 1

Insert

shStk16-1 (Stk16 Mouse)

Use

AAV and RNAi

Promoter

CBA

Available since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only

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(pRZ294) AAV: U6-gRNA-EF1a-ZsGreen

Plasmid

#254586

Purpose

AAV backbone expressing a U6-driven sgRNA with SapI spacer and ZsGreen from the EF1a promoter

Depositor

Jesse Engreitz

Insert

sgRNA with SapI spacer

Use

AAV

Available since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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(pRZ115) AAV: U6-gRNA-EF1a-mCherry

Plasmid

#254584

Purpose

AAV backbone expressing a U6-driven sgRNA with SapI spacer and mCherry from the EF1a promoter

Depositor

Jesse Engreitz

Insert

sgRNA with SapI spacer

Use

AAV

Available since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-S5E2-FingR-PSD95-mGL

Plasmid

#217533

Purpose

Genetically encoded fluorescent probe for labelling endogenous excitatory synapses on PV interneurons in vivo

Depositor

Peter Scheiffele

Publication

Okur et al bioRxiv 2023

Insert

ZnF-FingR-PSD95-mGreenLantern (Dlg4 Mouse)

Use

AAV

Tags

mGreenLantern

Expression

Mammalian

Promoter

S5E2 enhancer

Available since

April 11, 2024

Availability

Academic Institutions and Nonprofits only

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pAT159_AAV_p3_PE7-C_hU6_epegRNA

Plasmid

#251105

Purpose

Encodes the C terminal of the PE7 prime editor in an AAV expression plasmid + pegRNA cloning casette

Depositor

Gerald Schwank

Publication

Talas et al Sci Transl Med. 2026 May 13;18(849):eaec

Insert

PE7 C-terminal

Use

AAV and CRISPR

Promoter

p3

Available since

May 14, 2026

Availability

Academic Institutions and Nonprofits only

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