We narrowed to 17,849 results for: Mut
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Plasmid#203372PurposeFor transfection and in vitro assayDepositorAvailable SinceJuly 1, 2025AvailabilityAcademic Institutions and Nonprofits only
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Tau BA 12->7 G303V
Plasmid#203373PurposeFor transfection and in vitro assayDepositorAvailable SinceJuly 1, 2025AvailabilityAcademic Institutions and Nonprofits only -
pRRL-SFFV_V5-CHIC2-C6S_Tomato
Plasmid#238128PurposeExpresses V5-tagged CHIC2 (with C6S mutation) with Tomato selectable marker.DepositorInsertV5-tagged CHIC2 with C6S mutation
UseTagsV5ExpressionMammalianMutationChanged cysteines from amino acids 102-109 to ser…PromoterSFFVAvailable SinceJuly 1, 2025AvailabilityAcademic Institutions and Nonprofits only -
pSMPPv2-Tau-RING (M72E/I18R)
Plasmid#233690PurposeExpression of Tau-RING I18R-M72E mutant in mammalian cellsDepositorInsertTau protein fused to TRIM21 RING domain carrying M72E/I18R mutations
UseLentiviralTagsExpressionMammalianMutationPromoterAvailable SinceApril 18, 2025AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetO-Chim-Pchi-Q61A
Plasmid#231520PurposeExpresses Pigoraptor chileana chimeric Sox mutant in mammalian cells, for lentivirus generationDepositorInsertPchi HMG Q61A flanked with N- and C-termini of mSox2
UseLentiviralTagsExpressionMutationPoint mutation at position 61 Q to A of the HMG d…PromoterAvailable SinceMarch 18, 2025AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-TetO-Chim-Pchi-Q61A/E64M
Plasmid#231521PurposeExpresses Pigoraptor chileana chimeric Sox mutant in mammalian cells, for lentivirus generationDepositorInsertPchi HMG Q61A/E64M flanked with N- and C-termini of mSox2
UseLentiviralTagsExpressionMutationPoint mutations at position 61 Q to A and 64 E to…PromoterAvailable SinceMarch 14, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAG391
Plasmid#226732PurposeExpresses a reporter for an alpha-helical OMM proteinDepositorAvailable SinceFeb. 10, 2025AvailabilityAcademic Institutions and Nonprofits only -
pPB9v2
Plasmid#210029PurposeContains cloning site for molecularly-tagged Cas9 gRNA constructs, inducible Cas9, rtTA-T2A-puroDepositorInsertsCas9
rtta-T2A-puro
UseCRISPRTagsSV40 NLS and nucleoplasmin NLSExpressionMammalianMutationPromoterEF-1α and TRE3GAvailable SinceFeb. 6, 2025AvailabilityAcademic Institutions and Nonprofits only -
pPB9P2
Plasmid#210030PurposeContains PE2 prime editing gRNA cloning site, inducible prime editor 2, rtTA-T2A-puroDepositorInsertsprime editor 2
rtta-T2A-puro
UseCRISPRTagsSV40 NLSExpressionMammalianMutationPromoterEF-1α and TRE3GAvailable SinceFeb. 6, 2025AvailabilityAcademic Institutions and Nonprofits only -
pPB758
Plasmid#210033PurposeContains inducible Cas7-P2A-Cas5-T2A-Cas8, rtTA-T2A-puroDepositorInsertsCas7-P2A-Cas5-T2A-Cas8
rtta-T2A-puro
UseCRISPRTagsSV40 NLSExpressionMammalianMutationPromoterEF-1α and TRE3GAvailable SinceFeb. 6, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCS2+ 3xFLAG-FEM1B C186S
Plasmid#230995PurposeTransient overexpression of mouse FEM1B in mammalian cells. Mutation abolishes substrate binding.DepositorInsertFEM1B (Fem1b Mouse)
UseTags3xFLAGExpressionMammalianMutationmutated Cys186 to SerPromoterAvailable SinceJan. 23, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCS2+ 3xFLAG-FEM1B L597A
Plasmid#230994PurposeTransient overexpression of catalytic null mouse FEM1B in mammalian cells. Mutation abolishes interaction with CUL2.DepositorInsertFEM1B (Fem1b Mouse)
UseTags3xFLAGExpressionMammalianMutationmutated Leu597 to AlaPromoterAvailable SinceJan. 23, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCas3-APOBEC1
Plasmid#229536PurposepMV_hyg encoding Cas3(wt)-rAPOBEC1 fusion construct and crRNA expression cassette. Respective crRNA spacer can be introduced via BsmBI restriction cloningDepositorInsertsrAPOBEC1
Cas3
Uracil glycosylase inhibitor
UseTagsXTENExpressionBacterial and YeastMutationcodon optimized for S.cerevisiae and codon optimi…PromoterAvailable SinceJan. 22, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCas3-CDA1
Plasmid#229534PurposepMV_hyg encoding Cas3(wt)-CDA1 fusion construct and crRNA expression cassette. Respective crRNA spacer can be introduced via BsmBI restriction cloningDepositorInsertsCas3
Cytidine deaminase
Uracil glycosylase inhibitor
UseTagsXTENExpressionBacterial and YeastMutationcodon optimized for S.cerevisiae and codon optimi…PromoterAvailable SinceJan. 22, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAG392
Plasmid#226749PurposeCRISPRi guide RNA against ATP13A1DepositorAvailable SinceOct. 24, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAG369
Plasmid#226748PurposeCRISPRi guide RNA against EMC2DepositorAvailable SinceOct. 24, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAG517
Plasmid#226735PurposeExpresses a reporter for an alpha-helical OMM proteinDepositorAvailable SinceOct. 24, 2024AvailabilityAcademic Institutions and Nonprofits only -
pICOZ-MAG-H181A
Plasmid#218300PurposeMammalian expression vector for expression of MAG transposase mutantDepositorInsertH181A mutant of MAG transposase
UseTagsExpressionMammalianMutationPromoterAvailable SinceOct. 23, 2024AvailabilityAcademic Institutions and Nonprofits only -
pICOZ-MAG-H181V
Plasmid#218301PurposeMammalian expression vector for expression of MAG transposase mutantDepositorInsertH181V mutant of MAG transposase
UseTagsExpressionMammalianMutationPromoterAvailable SinceOct. 23, 2024AvailabilityAcademic Institutions and Nonprofits only -
pICOZ-MAG-K241R
Plasmid#218302PurposeMammalian expression vector for expression of MAG transposase mutantDepositorInsertK241R mutant of MAG transposase
UseTagsExpressionMammalianMutationPromoterAvailable SinceOct. 23, 2024AvailabilityAcademic Institutions and Nonprofits only -
pET3a.H2B-K120C
Plasmid#224706PurposeExpresses Human H2B K120C mutant in bacterial cells for fluorescent labelling of histone octamersDepositorAvailable SinceOct. 18, 2024AvailabilityAcademic Institutions and Nonprofits only -
TLNRD1(4H)-2T_pET47b
Plasmid#224069PurposeBacterial expression of the 4-helix bundle of TLNRD1 (residues 143-273) containing the mutations L191T/A225T, fused to an N-terminal hexa-histidine tag. HRV-3C cleavage siteDepositorInserttlnrd1 (TLNRD1 Human)
UseTags6xHISExpressionBacterialMutationL191T/A225T double mutant; reduces affinity of TL…PromoterT7Available SinceAug. 26, 2024AvailabilityIndustry, Academic Institutions, and Nonprofits -
TLNRD1(4H)-2E_pET151
Plasmid#224068PurposeBacterial expression of the 4-helix bundle of TLNRD1 (residues 143-273) containing the mutations K192E/R233E, fused to an N-terminal hexa-histidine tag. TEV cleavage siteDepositorInserttlnrd1 (TLNRD1 Human)
UseTags6xHIS; V5ExpressionBacterialMutationK192E/R233E double mutant; prevents actin binding…PromoterT7Available SinceAug. 26, 2024AvailabilityIndustry, Academic Institutions, and Nonprofits -
pGGI_Myr-YFP-MiniTurboID
Plasmid#222432PurposePotential plasma membrane control.DepositorInsertMiniTurboID (BirA mutant)
UseGolden gate / green gate compatible cloning vectorTagsLinker, Myr, and YFPExpressionMutationaa1-63 deleted; Q65P, I87V, R118S, E140K, Q141R, …PromoterAvailable SinceJuly 29, 2024AvailabilityAcademic Institutions and Nonprofits only -
pRAR107
Plasmid#185037Purpose400 nt l31 promoter region, l31 5'UTR AGA74-76GAG mutation, 90 nt of l31 coding region, glycine linker, sfGFP, trrnBDepositorInsertL31-sfGFP
UseTagsExpressionBacterialMutationAGA74-76GAG mutation of rpmE 5'UTR, Only fir…PromoterAvailable SinceJuly 15, 2024AvailabilityAcademic Institutions and Nonprofits only -
pCPH2A.X_K5Q-GS3
Plasmid#204746PurposeExpression of Cas9 and human H2AX with the K5Q mutationDepositorInsertH2AX K5Q (H2AX Human)
UseTagsExpressionMammalianMutationH2AX with the K5Q mutationPromoterAvailable SinceJune 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
pCPH2A.X_K5R-GS3
Plasmid#204747PurposeExpression of Cas9 and human H2AX with the K5R mutationDepositorInsertH2AX K5R (H2AX Human)
UseTagsExpressionMammalianMutationH2AX with the K5R mutationPromoterAvailable SinceJune 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
pCPH2A.X_K134L-GS3
Plasmid#204750PurposeExpression of Cas9 and human H2AX with the K134L mutationDepositorInsertH2AX K134L (H2AX Human)
UseTagsExpressionMammalianMutationH2AX with the K134L mutationPromoterAvailable SinceJune 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
pCPH2A.X_K134M-GS3
Plasmid#204751PurposeExpression of Cas9 and human H2AX with the K134M mutationDepositorInsertH2AX K134M (H2AX Human)
UseTagsExpressionMammalianMutationH2AX with the K134M mutationPromoterAvailable SinceJune 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
pCPH2A.X_K134A-GS3
Plasmid#204752PurposeExpression of Cas9 and human H2AX with the K134A mutationDepositorInsertH2AX K134A (H2AX Human)
UseTagsExpressionMammalianMutationH2AX with the K134A mutationPromoterAvailable SinceJune 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
pEGFP-C1-SHTN1LRRR>GGG
Plasmid#209562PurposeMammalian expression of Shtn1 long isoform with RG mutationDepositorInsertShtn1 long isoform with RG mutation (4930506M07Rik Mouse)
UseTagsExpressionMammalianMutationRRR to GGGPromoterAvailable SinceMarch 7, 2024AvailabilityAcademic Institutions and Nonprofits only -
pPAP_scFv_V50A
Plasmid#183734PurposeExpresses anti-lysozyme scFv antibody with V50A mutation on MFalpha signalDepositorInsertAnti-lysozyme scFv
UseTagsHis6-tagExpressionYeastMutationV50A mutation in MFalpha signalPromoterAOX1 promoterAvailable SinceFeb. 29, 2024AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-VcnTS-E1015A-E1021A
Plasmid#213417PurposeVinculin tension sensor (VcnTS) with both directionally asymmetric, force strengthening (DAFS) variant point mutations (E1015A and E1021A).DepositorInsertVcnTS-E1015A-E1021A (VCL Synthetic, Chicken)
UseTagsExpressionMammalianMutationMutated vinculin glutamic acid 1015 and 1021 to a…PromoterCMVAvailable SinceFeb. 15, 2024AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-VcnCS-E1015A-E1021A
Plasmid#213414PurposeVinculin conformation sensor (VcnCS) with both directionally asymmetric, force strengthening (DAFS) variant point mutations (E1015A and E1021A).DepositorInsertVcnCS-E1015A-E1021A (VCL Synthetic, Chicken)
UseTagsExpressionMammalianMutationMutated vinculin glutamic acid 1015 and 1021 to a…PromoterCMVAvailable SinceFeb. 15, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-syn-FLEX-tTA
Plasmid#178516PurposeAAV vector for Cre recombinase dependent tetracycline-controlled transactivator (tTA) expressionDepositorInserttTA
UseAAVTagsExpressionMammalianMutationPromoterAvailable SinceJan. 24, 2024AvailabilityAcademic Institutions and Nonprofits only -
CCM2_I432D_eGFP
Plasmid#208879PurposeExpress eGFP-CCM2 with the I432D mutation in mammalian cells.DepositorAvailable SinceDec. 22, 2023AvailabilityAcademic Institutions and Nonprofits only -
CCM2_W421AD422A_eGFP
Plasmid#208880PurposeExpress eGFP-CCM2 with the W421A and D422A mutations in mammalian cells.DepositorInsertCCM2 (CCM2 Human)
UseTagseGFPExpressionMammalianMutationmutations W421A and D422APromoterAvailable SinceDec. 22, 2023AvailabilityAcademic Institutions and Nonprofits only -
CCM2_I428S_eGFP
Plasmid#208878PurposeExpress eGFP-CCM2 with the I428S mutation in mammalian cells.DepositorAvailable SinceDec. 22, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-syn-mCre
Plasmid#178515PurposeAAV vector for mCre recombinaseDepositorInsertmCre
UseAAV and Cre/LoxTagsExpressionMammalianMutationPromoterAvailable SinceDec. 20, 2023AvailabilityAcademic Institutions and Nonprofits only -
pFSynW SYT9 D197, 199N IRES GFP
Plasmid#195701PurposeLentiviral plasmid encoding SYT9 with D197, 199N mutations followed by an internal ribosomal entry site followed by EGFP under the human synapsin promoterDepositorInsertSyt9 (Syt5 Mouse)
UseLentiviralTagsExpressionMutationfull-length mouse SYT9 with D197, 199N mutationsPromoterAvailable SinceOct. 16, 2023AvailabilityAcademic Institutions and Nonprofits only