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Plasmid#37198DepositorInsertFokI (fused to Rosa L6 ZFN)
UseZfn expressionTagsHA, ROSA26 eZFNs L6, and SV40 NLSExpressionMammalianMutationQ486E, I499L and N496DPromoterCMVAvailable sinceJuly 19, 2012AvailabilityAcademic Institutions and Nonprofits only -
pGE144 (MutaEco; aTC-induced)
Plasmid#189824PurposeExpresses MutaEco for generating mutations in the E. coli genome (aTC-induced)DepositorInsertEcoRNAPα-PmCDA1
UseTagsExpressionBacterialMutationPromotertetR/tetA promoterAvailable sinceSept. 16, 2022AvailabilityAcademic Institutions and Nonprofits only -
pMX-HA-UbvG08_MUT-IRES-GFP
Plasmid#75031PurposeRetroviral vector with ubiquitin variant with reverted mutations L69P and V70L (i53-DM mutant)DepositorInsertUbiquitin
UseRetroviralTagsHA and IRES-eGFPExpressionMutationUbvG08 with I44A, P69L, and L70V mutations and no…PromoterAvailable sinceJune 30, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
hRIP3 GFP RHIM mut
Plasmid#41385DepositorInsertRIP3 (RIPK3 Human)
UseTagsGFPExpressionMammalianMutationRHIM mutant (AAAA-459-462)PromoterCMVAvailable sinceDec. 4, 2012AvailabilityAcademic Institutions and Nonprofits only -
pGL3-OF (mutant TCF-4 sites)
Plasmid#16559DepositorInsertTCF-4 binding sites (TCF4 Human)
UseLuciferaseTagsLuciferaseExpressionMammalianMutation3 copies of mutant Tcf-4 binding sitesPromoterAvailable sinceMarch 28, 2008AvailabilityAcademic Institutions and Nonprofits only -
pRK5-mEGFP-FOXC1-MUT
Plasmid#194567PurposeMammalian Expression of mEGFP-FOXC1 Mutant (Q200Rfs*109) Fusion ProteinDepositorInsertFOXC1 (FOXC1 Human)
UseTagsmEGFPExpressionMammalianMutationQ200Rfs*109PromoterAvailable sinceFeb. 22, 2023AvailabilityAcademic Institutions and Nonprofits only -
p CIneo-RL-Let7-3xBulgeB-mut
Plasmid#115369PurposeExpression vector to produce humanized Renilla luciferase with three mutated (seed-sequence mutations) partially complementary binding sites for human let-7 miRNA in the 3'UTRDepositorInsertRenilla Luciferase
UseLuciferaseTagsExpressionMammalianMutationPromoterCMVAvailable sinceDec. 3, 2018AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-Flag-Tet3 CD Mut
Plasmid#72222PurposeExpress flag-tagged mouse Tet3 catalytic domain - catalytic dead mutant.DepositorInsertTen-Eleven Translocation 3
UseTagsflagExpressionMammalianMutationThe plasmid expresses TET3 catalytic domain (cata…PromoterCMVAvailable sinceMay 1, 2018AvailabilityAcademic Institutions and Nonprofits only -
pCMV-erHRP(N175S mutant)
Plasmid#79909PurposeerHRP(N175S mutant) pCMV backboneDepositorInserterHRP(N175S mutant)
UseTagsHA tagExpressionMammalianMutationN175S mutationPromoterCMVAvailable sinceJuly 22, 2016AvailabilityAcademic Institutions and Nonprofits only -
pDEST_FLAG-HUWE1_UBA/UIM-mut
Plasmid#187152Purposemammalian cell expression of FLAG-HUWE1 M1328A/F1330A/A1376G/S1382ADepositorInsertHUWE1 (HUWE1 Human)
UseTags1xFLAGExpressionMammalianMutationM1328A/F1330A/A1376G/S1382APromoterAvailable sinceAug. 22, 2022AvailabilityAcademic Institutions and Nonprofits only -
Marathon-RT tetramutant for Split-PE (pEH101)
Plasmid#190109PurposeExpresses Marathon-RT tetramutant (D14R-D74R-N116K-N197R)DepositorInsertMarathon-RT
UseTagsbpNLSExpressionMammalianMutationD14R, D74R, N116K, N197RPromoterCMVAvailable sinceSept. 26, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-EFS-DIO-GRAB_CRFmut
Plasmid#208663PurposeExpresses the genetically-encoded fluorescent corticotropin-releasing factor (CRF) control sensor GRAB_CRFmut in a cre-dependent mannerDepositorInsertGPCR activation based corticotropin-releasing factor (CRF) contorl sensor GRAB_CRFmut
UseAAVTagsExpressionMutationPromoterEFSAvailable sinceOct. 30, 2023AvailabilityAcademic Institutions and Nonprofits only -
dCas9-CRY2Clust-FUSN-mut
Plasmid#200970Purposeinduction of phase-separated condensate mediated by FUSN-IDR mutantDepositorInsertFUSNmut
UseLentiviralTagsExpressionBacterial and MammalianMutation15 Tyr-to-Ser substitutionsPromoterAvailable sinceMay 22, 2023AvailabilityAcademic Institutions and Nonprofits only -
mRIP3 GFP RHIM mut
Plasmid#41384DepositorInsertRIP3 (Ripk3 Mouse)
UseTagsGFPExpressionMammalianMutationRHIM mutantPromoterCMVAvailable sinceDec. 4, 2012AvailabilityAcademic Institutions and Nonprofits only -
pAAV-EFS-DIO-GRAB_OTmut
Plasmid#185389PurposeExpresses the genetically-encoded fluorescent oxytocin(OT) sensor GRAB_OT1.0 in a cre-dependent mannerDepositorInsertGPCR activation based oxytocin control sensor GRAB_OTmut
UseAAVTagsExpressionMutationPromoterEFSAvailable sinceJuly 6, 2022AvailabilityAcademic Institutions and Nonprofits only -
CLXSN 5myc-CDC6-mut
Plasmid#109333Purposeexpress tagged Cdc6 mutantDepositorInsertCDC6 (CDC6 Human)
UseRetroviralTags5x MycExpressionMammalianMutationR56A, L59A, K81A, E82A, N83APromoterAvailable sinceJuly 25, 2018AvailabilityAcademic Institutions and Nonprofits only -
pCI-MS2V5-PABPC1 MLLEmut
Plasmid#65808Purposeexpression of PABPC1-MS2 fusion. Mutation of C-terminal MLLE domain.DepositorInsertPABPC1 (PABPC2 Human)
UseTagsMS2 stem loops and V5ExpressionMammalianMutationMLLEmutPromoterCMVAvailable sinceSept. 17, 2015AvailabilityAcademic Institutions and Nonprofits only -
INPP5D-eGFP D673G mutant
Plasmid#161999PurposeMammalian expression vector, containing a GFP tagged phosphatase dead version of INPP5D (D673G)DepositorInsertINPP5D (INPP5D Human)
UseTagseGFPExpressionMammalianMutationD673GPromoterAvailable sinceDec. 3, 2020AvailabilityAcademic Institutions and Nonprofits only -
CaV1.3e[8a,11,31b,Δ32,42a] mut
Plasmid#26576DepositorInsertCACNA1D (Cacna1d Rat)
UseTags6XHis and V5ExpressionMammalianMutationContains exons 8a, 11, 31b and 42a.Deletion of ex…PromoterAvailable sinceJan. 31, 2011AvailabilityAcademic Institutions and Nonprofits only -
Luc-SIRT1 mutant 3'UTR
Plasmid#20380DepositorInsertSIRT1 (SIRT1 Human)
UseLuciferaseTagsExpressionMutationmutant 3'UTR of SIRT1 (ACACCCACCAAGGACCATTAG…PromoterAvailable sinceMay 1, 2009AvailabilityAcademic Institutions and Nonprofits only -
pEGFP C3-Lats1-PY1+2 mutant
Plasmid#19054DepositorInsertLarge tumor suppressor kinase 1, N mutant (LATS1 Human)
UseTagsEGFPExpressionMammalianMutationPY1 mutant, (Tyrosine 376 changed to Alanine) and…PromoterAvailable sinceSept. 8, 2008AvailabilityAcademic Institutions and Nonprofits only -
pKH143_EGFP-YIPF3 LIR mut
Plasmid#214975PurposeGFP tagged LIR mutant YIPF3DepositorInsertGFP-YIPF3_mut (YIPF3 Human)
UseLentiviralTagsExpressionMutationLIR mutantPromoterAvailable sinceApril 29, 2024AvailabilityAcademic Institutions and Nonprofits only -
pFLEX-m-cyclin D1 -T286A mutant
Plasmid#86792Purposemammalian expression of cyclin D1 T286A mutantDepositorInsertcyclin D1 (Ccnd1 Mouse)
UseTagsFLAGExpressionMammalianMutationT286APromoterAvailable sinceFeb. 14, 2017AvailabilityAcademic Institutions and Nonprofits only -
pET30a-His6-ABP-LOXCATmut
Plasmid#139972PurposeA control for His6-ABP-LOXCAT where LOX is catalytically dead (mutations H265A and R268A)DepositorInsertA fusion of lactate oxidase from A. viridans and catalase from E. coli
UseTagsHis6ExpressionBacterialMutationMutation in H265A and R268A in LOX (used original…PromoterT7Available sinceSept. 16, 2020AvailabilityAcademic Institutions and Nonprofits only -
betaTrCP mVenus mutant reporter
Plasmid#192459PurposeFluorescent reporter for beta-TrCP with a non-degradable mutation. Used as a control.DepositorInsertCdC25B
UseLentiviralTagsSV40 NLS and mVenusExpressionMammalianMutationaa198-338 of CDC25B. betaTrCP degron sequence (aa…PromoterEF1alphaAvailable sinceOct. 31, 2022AvailabilityAcademic Institutions and Nonprofits only -
pLL5.0 hCortKD-Flcortmut3YD EGFP
Plasmid#187264PurposeLentiviral expression of shRNA targeting Cortactin + reconstitution of Cortactin3YD mutantDepositorInsertCortactin (CTTN Human)
UseLentiviralTagsEGFPExpressionMutation3YD (Y412, Y470, Y486)PromoterU6, 5'LTRAvailable sinceSept. 26, 2022AvailabilityAcademic Institutions and Nonprofits only -
pTCF176 HLA-A*02:01 (CD8 mut)
Plasmid#180459PurposeE. coli expression of soluble MHC proteinDepositorInsertHLA-A*02:01 (CD8 mut)
UseTagsBSP41ExpressionBacterialMutationD227K, T228A, replacement of transmembrane domain…PromoterAvailable sinceFeb. 24, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCGN-ELK-1 Ets mut
Plasmid#27157PurposeFor mammalian expression of human Elk-1 with an HA tag and a mutation in the Ets DNA binding domainDepositorInsertELK1 (ELK1 Human)
UseTagsHAExpressionMammalianMutationR62E/R65E/Y66DPromoterAvailable sinceDec. 22, 2010AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3 myc card9 mutant
Plasmid#16254DepositorInsertcard9 mutant (CARD9 Human)
UseTagsmycExpressionMammalianMutationS528A, T531A, T533A, S536APromoterAvailable sinceNov. 21, 2007AvailabilityAcademic Institutions and Nonprofits only -
PTEN-mut (negative control)
Plasmid#86646Purposeexpression of control shRNADepositorInsertPTEN (control)
UseRNAiTagsExpressionMammalianMutationPromoterH1Available sinceJune 20, 2017AvailabilityAcademic Institutions and Nonprofits only