We narrowed to 13,316 results for: ache
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Plasmid#20557DepositorAvailable SinceOct. 27, 2009AvailabilityAcademic Institutions and Nonprofits only
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pIND20-KNL1-s24a_s60a-dCas9
Plasmid#248563PurposeA CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeresDepositorInsertKNL1-s24a_s60a-dCas9
UseCRISPRTagsHA, 2xNLSExpressionMammalianMutationKNL1 S24A, S60A; Cas9 D10A, H840APromoterTRE, miniCMVAvailable SinceFeb. 23, 2026AvailabilityAcademic Institutions and Nonprofits only -
pHAGE-KNL1-s24a_s60a-dCas9
Plasmid#248568PurposeA CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeresDepositorInsertKNL1-s24a_s60a-dCas9
UseCRISPRTagsHA, 2xNLSExpressionMammalianMutationKNL1 S24A, S60A; Cas9 D10A, H840APromoterCMV, TetO2Available SinceFeb. 6, 2026AvailabilityAcademic Institutions and Nonprofits only -
pLJC2-TOM20-HK2-3xFLAG
Plasmid#239245PurposeTOM20-HK2 lentiviral overexpression vectorDepositorUseLentiviralTags3xFLAGExpressionMammalianMutationInsert contains the set of silent mutations descr…PromoterCMVAvailable SinceJan. 26, 2026AvailabilityAcademic Institutions and Nonprofits only -
pLJC6-TOM20-HK2-3xFLAG
Plasmid#239256PurposeTOM20-HK2 lentiviral overexpression vectorDepositorUseLentiviralTags3xFLAGExpressionMammalianMutationInsert contains the set of silent mutations descr…PromoterUbcAvailable SinceJan. 26, 2026AvailabilityAcademic Institutions and Nonprofits only -
pSico-syn-mGreenLantern:KASH-TVA-oG-6xMBS-WPRE-bGHpA
Plasmid#231010PurposeLentiviral helper virus for G-deleted rabies tracing. mGreenLantern:KASH fluorescence is not visible without immunostaining.DepositorInsertsUseLentiviralTagsKASHMutationPlease note that mGreenLantern-KASH is not visibl…Promoterhuman synapsin IAvailable SinceDec. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
pSico-U6-tornado:6xMBS:8G8ApA-syn-GFP-TVA-oG-WPRE-bGHpA
Plasmid#231013PurposeLentiviral helper virus for G-deleted rabies tracing, with U6-driven transcript amenable for nuclear capture in the presence of RVdG expressing MS2-KASH.DepositorInsertsEnhanced GFP
TVA (CD320 Chicken)
optimized G
Tornado expression system containing 6X MS2 binding sites and 8G8A synthetic poly A capture sequence
UseLentiviralPromoterhuman U6 and human synapsin IAvailable SinceDec. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-hU6-FOXP2_sgRNA1-hUbC-dCas9-KRAB-T2a-GFP
Plasmid#231022PurposeAll-in-one lentiviral vector (Gersbach lab design) for CRISPRi targeting FOXP2DepositorInsertFOXP2 sgRNA
UseCRISPR and LentiviralExpressionMammalianPromoterU6Available SinceDec. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-hU6-FOXP2_sgRNA2-hUbC-dCas9-KRAB-T2a-GFP
Plasmid#231023PurposeAll-in-one lentiviral vector (Gersbach lab design) for CRISPRi targeting FOXP2DepositorInsertFOXP2 sgRNA
UseCRISPR and LentiviralExpressionMammalianPromoterhU6Available SinceDec. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-hU6-ROBO2_sgRNA-hUbC-dCas9-KRAB-T2a-GFP
Plasmid#231024PurposeAll-in-one lentiviral vector (Gersbach lab design) for CRISPRi targeting ROBO2DepositorInsertROBO2 sgRNA
UseCRISPR and LentiviralExpressionMammalianPromoterhU6Available SinceDec. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-hU6-NTC_sgRNA-hUbC-dCas9-KRAB-T2a-GFP
Plasmid#231025PurposeAll-in-one lentiviral vector (Gersbach lab design) for CRISPRi with non-targeting control sgRNADepositorInsertNon-targeting control sgRNA
UseCRISPR and LentiviralExpressionMammalianPromoterhU6Available SinceDec. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLCKO-CMV-cMyc-UBC-IRES-Blasti
Plasmid#242462PurposeExpresses human UBC protein with an N-terminal cMyc tag enabling UBC pull down along with a blasticidin selection marker.DepositorAvailable SinceDec. 4, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-puro-EF1A-3XFLAG-hASB8_G198R
Plasmid#242465PurposeExpresses human ASB8 protein with an N-terminal 3xFLAG tag along with a puromycin selection marker. The G198R mutation disrupts XPO1 binding.DepositorInsertASB8 (ASB8 Human)
UseLentiviralTags3xFLAGExpressionMammalianMutationG198RPromoterEF1AAvailable SinceNov. 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-puro-EF1A-3XFLAG-hASB8_L199R
Plasmid#242466PurposeExpresses human ASB8 protein with an N-terminal 3xFLAG tag along with a puromycin selection marker. The L199R mutation disrupts XPO1 binding.DepositorInsertASB8 (ASB8 Human)
UseLentiviralTags3xFLAGExpressionMammalianMutationL199RPromoterEF1AAvailable SinceNov. 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-puro-EF1A-3XFLAG-hASB8_L199G
Plasmid#242467PurposeExpresses human ASB8 protein with an N-terminal 3xFLAG tag along with a puromycin selection marker. The L199G mutation disrupts XPO1 binding.DepositorInsertASB8 (ASB8 Human)
UseLentiviralTags3xFLAGExpressionMammalianMutationL199GPromoterEF1AAvailable SinceNov. 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-puro-EF1A-3XFLAG-hASB8_ANK3-4
Plasmid#242468PurposeExpresses human ASB8 protein with an N-terminal 3xFLAG tag along with a puromycin selection marker. The ANK3-4 mutations disrupt XPO1 binding.DepositorInsertASB8 (ASB8 Human)
UseLentiviralTags3xFLAGExpressionMammalianMutationANK3-4 = R87A - E95A - K96A - W124G - K128GPromoterEF1AAvailable SinceNov. 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
pGL4-CMV-myc-XPO1_H10-11
Plasmid#242471PurposeExpresses human XPO1 protein with an N-terminal cMyc tag. The H10-11 mutations disrupt ASB8 binding.DepositorInsertXPO1 (XPO1 Human)
TagscMycExpressionMammalianMutationXPO1 H10-11 = E478A - H481A - V484G - N485G - T48…PromoterCMVAvailable SinceNov. 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLV-puro-EF1A-Tag100-hASB8_G198R
Plasmid#242461PurposeExpresses human ASB8 protein with an N-terminal Tag100 along with a puromycin selection marker. The G198R mutation disrupts XPO1 binding.DepositorInsertASB8 (ASB8 Human)
UseLentiviralTagsTag100ExpressionMammalianMutationG198RPromoterEF1AAvailable SinceNov. 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLCKO-CMV-cMyc-UBC_K7R-IRES-Blasti
Plasmid#242463PurposeExpresses human UBC protein with an N-terminal cMyc tag enabling UBC pull down along with a blasticidin selection marker. The K7R mutations prevent ubiquitin chain elongation.DepositorAvailable SinceNov. 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
pGEX-TRIP12-HECT
Plasmid#241818PurposeExpesses GST-TRIP12 for protein purificationDepositorAvailable SinceSept. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
pYO1022
Plasmid#242503PurposeExpression of ZZ-3xTEV-HsATG14 and ZZ-3xTEV-HsBECN1 in mammalian cellsDepositorTagsZZ-3xTEVExpressionMammalianPromoterCAG and CMVAvailable SinceSept. 9, 2025AvailabilityAcademic Institutions and Nonprofits only -
pBI121::chitRatioGFP:LAAQ
Plasmid#240451PurposeExpression of indicator protein fusion (modified ratiometric pHluorin & low affinity Aequorin) for monitoring calcium concentrations and pH in cell walls of higher plants. See Resource Information.DepositorInsertFusion of chitinase signal, soluble modified ratiometric pHluorin and low affinity Aequorin (D119A)
ExpressionBacterial and PlantMutationRatiometric GFP (ratiometric pHluorin) (PMID 9671…PromoterCauliflower mosaic virus 35S promoter (GenBank AJ…Available SinceSept. 4, 2025AvailabilityAcademic Institutions and Nonprofits only -
Mirror GFP[ENE(C8351G)-mascRNA(mut 8356-8370)](pAVA3871)
Plasmid#239352PurposeExpresses TEV protease and tandemly-repeated GFP fluorescent proteins to amplify the fluorescence signal produced by a single transcription unit of MALAT1 ENE(C8351G)-mascRNA(mut 8356-8370) reporter.DepositorInsertMALAT1 ENE(C8351G)-mascRNA(mut 8356-8370)
ExpressionMammalianMutationMALAT1 ENE(C8351G)-mascRNA(mut 8356-8370: ctacgac…Available SinceAug. 26, 2025AvailabilityAcademic Institutions and Nonprofits only -
LentiCRISPR-B_2xsgRNAs_UPF3A/UPF3B (pAVA3129)
Plasmid#239329PurposeLentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting UPF3A and UPF3BDepositorInsertU6-driven sgRNA1 targting UPF3A and 7SK-driven sgRNA2 targeting UPF3B (UPF3B Human)
UseCRISPR and LentiviralAvailable SinceAug. 4, 2025AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-GSDMD_H270A
Plasmid#224701PurposeExpression of mutated Gasdermin D_H270A (GSDMD_H270A) in transfected mammalian cell linesDepositorAvailable SinceJuly 2, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits -
pcDNA3.1-GSDMD_Q29A
Plasmid#224702PurposeExpression of mutated Gasdermin D_Q29A (GSDMD_Q29A) in transfected mammalian cell linesDepositorAvailable SinceJuly 2, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits -
pcDNA3.1-GSDMD_Q29A_H270A
Plasmid#224703PurposeExpression of mutant Gasdermin D_Q29A_H270A (GSDMD_Q29A_H270A) in transfected mammalian cell linesDepositorInsertGSDMD_Q29A_H270A (GSDMD Human)
TagsFLAGExpressionMammalianMutationQ29A and H270APromoterCMVAvailable SinceJuly 2, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits -
pcDNA3.1-GSDMD_D275A
Plasmid#224704PurposeExpression of mutated Gasdermin D_D275A (GSDMD_D275A) in transfected mammalian cell linesDepositorAvailable SinceJuly 2, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits -
pcDNA3.1-GSDMD_H270A_D275A
Plasmid#224705PurposeExpression of mutated Gasdermin D_H270A_D275A (GSDMD_D275A) in transfected mammalian cell linesDepositorInsertGSDMD_Q29A_H270A (GSDMD Human)
TagsFLAGExpressionMammalianMutationH270A and D275APromoterCMVAvailable SinceJuly 2, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits -
pMCB320 sgCdkn1a.1
Plasmid#227945PurposesgRNA targeting Cdkn1a, mCherry, puromycin resistance, Mammalian expression, Mouse targeting, lentiviral, CRISPRDepositorAvailable SinceApril 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
pMCB320 sgCdkn1a.2
Plasmid#227946PurposesgRNA targeting Cdkn1a, mCherry, puromycin resistance, Mammalian expression, Mouse targeting, lentiviral, CRISPRDepositorAvailable SinceApril 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
AAV-FLEX-CAG_G-PTEN
Plasmid#227438PurposeAn AAV backbone for expression of the G-PTEN sensor under the CAG promoter, in a Cre dependent manner.DepositorInsertG-PTEN sensor (Pten Rat)
UseAAVTagsCD-sREACh and mEGFPExpressionMammalianMutationR14GPromoterpCAGAvailable SinceApril 23, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCBh-T7-SpG-P2A-mTagBFP2(RAS3583)
Plasmid#223110PurposepCBh Human expression plasmid for SpG with with C-term BPNLS-P2A-mTagBFP2DepositorInserthuman codon optimized nuclease SpG-P2A-mTagBFP2
UseCRISPRTagsBPNLS-3xFLAG-P2A-mTagBFP2ExpressionMammalianMutationSpG=D1135L/S1136W/G1218K/E1219Q/R1335Q/T1337RPromoterCMV and T7Available SinceApril 23, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCBh-T7-SpCas9-P2A-mTagBFP2(RAS3575)
Plasmid#223111PurposepCBh Human expression plasmid for SpCas9 with with C-term BPNLS-P2A-mTagBFP2DepositorInserthuman codon optimized nuclease SpCas9-P2A-mTagBFP2
UseCRISPRTagsBPNLS-3xFLAG-P2A-mTagBFP2ExpressionMammalianPromoterCMV and T7Available SinceApril 23, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCAG-SpCas9-P2A-EGFP (MSP2582)
Plasmid#223067PurposepCAG human codon optimized wild-type SpCas9 expression plasmid with C-terminal NLS(SV40)-3xFLAG-P2A-EGFPDepositorInserthuman codon optimized SpCas9-P2A-EGFP
UseCRISPRTagsNLS(SV40)-3xFLAG-P2A-EGFPExpressionMammalianPromoterCAGAvailable SinceApril 23, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-EGFP-TEV-GST (I224A/L227A; deltaLIR3)
Plasmid#223775PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsEGFP-TEV-GSTExpressionBacterialMutationI224A/L227A; deletion of LIR3Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-EGFP-TEV-GST (I307A/V310A; deltaLIR4)
Plasmid#223776PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsEGFP-TEV-GSTExpressionBacterialMutationI307A/V310A; deletion of LIR4Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pFastBac-Dual_BNIP3(1-158aa)-THROMBIN-GST (E44A L47A D49A A50K Q51A; deltaWIPI2)
Plasmid#223777PurposeExpression of recombinant protein for purificationDepositorInsertBNIP3 soluble part (BNIP3 Human)
TagsThrombin cleavage-GSTExpressionInsectMutationE44A L47A D49A A50K Q51A; disrupts WIPI2 bindingAvailable SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pGEX4T1_GST-EGFP-ATG13_IDR_191-517aa_(M196-H214 11xA)
Plasmid#223779PurposeExpression of recombinant protein for purificationDepositorInsertATG13 IDR (ATG13 Human)
TagsGST-EGFPExpressionBacterialMutationexpresses aa 191-517, with M196A S197A R199A G202…Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-EGFP-TEV-GST (I224A/L227A/W276A/I279A; deltaLIR1+3)
Plasmid#223780PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsEGFP-TEV-GSTExpressionBacterialMutationI224A/L227A/W276A/I279A; deletion of LIR1+3Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-EGFP-TEV-GST (W276A/I279A/I307A/V310A; deltaLIR1+4)
Plasmid#223781PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsEGFP-TEV-GSTExpressionBacterialMutationW276A/I279A/I307A/V310A; deletion of LIR1+4Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-EGFP-TEV-GST (Y213A/I216A/W276A/I279A; deltaLIR1+2)
Plasmid#223782PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsEGFP-TEV-GSTExpressionBacterialMutationY213A/I216A/W276A/I279A; deletion of LIR1+2Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-EGFP-TEV-GST (Y213A/I216A; deltaLIR2)
Plasmid#223783PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsEGFP-TEV-GSTExpressionBacterialMutationY213A/I216A; deletion of LIR2Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-EGFP-TEV-GST (I224A/L227A/W276A/I279A/I307A/V310A; deltaLIR1+3+4)
Plasmid#223784PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsEGFP-TEV-GSTExpressionBacterialMutationI224A/L227A/W276A/I279A/I307A/V310A; deletion of …Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-THROMBIN-GST (I224A/L227A/W276A/I279A; deltaLIR1+3)
Plasmid#223754PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsThrombin cleavage-GSTExpressionBacterialMutationexpresses aa 1-465, with I224A/L227A/W276A/I279A;…Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-THROMBIN-GST (W276A/I279A/I307A/V310A; deltaLIR1+4)
Plasmid#223755PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsThrombin cleavage-GSTExpressionBacterialMutationexpresses aa 1-465, with W276A/I279A/I307A/V310A;…Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-THROMBIN-GST (I224A/L227A/W276A/I279A/I307A/V310A; deltaLIR1+3+4)
Plasmid#223756PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsThrombin cleavage-GSTExpressionBacterialMutationexpresses aa 1-465, with I224A/L227A/W276A/I279A/…Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pGEX4T1_GST-TEV-EGFP-ATG13_IDR_191-517aa_(M196A_S197A_R199A)
Plasmid#223761PurposeExpression of recombinant protein for purificationDepositorInsertATG13 IDR (ATG13 Human)
TagsGST-TEV-EGFPExpressionBacterialMutationexpresses aa 191-517, with M196A S197A R199A (par…Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_FUNDC1(1-50aa)-THROMBIN-GST (Y18A/L21A; deltaLIR)
Plasmid#223739PurposeExpression of recombinant protein for purificationDepositorInsertFUNDC1 soluble part, mutant (FUNDC1 Human)
TagsThrombin cleavage-GSTExpressionBacterialMutationY18A/L21A; deletion of LIRAvailable SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pETDuet1_BCL2L13(1-465aa)-EGFP-TEV-GST (W276A/I279A; deltaLIR1)
Plasmid#223746PurposeExpression of recombinant protein for purificationDepositorInsertBCL2L13 soluble part (BCL2L13 Human)
TagsEGFP-TEV-GSTExpressionBacterialMutationW276A/I279A; deletion of LIR1Available SinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only