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Plasmid#71258Purposeluciferase reporter with 3 copies of the stromelylisin gene AP-1 site in front of hGM-CSF -55 to +28 minimal promoterDepositorInsert3 copies of an AP-1 site from the human Stromelysin-1 gene (MMP3 Human)
UseLuciferaseTagsluciferaseExpressionMammalianMutationPromoterGM-CSF minimalAvailable sinceDec. 4, 2015AvailabilityAcademic Institutions and Nonprofits only -
pGL3 1 kb prom. + Enhancer CD274
Plasmid#107005PurposeModified Luciferase expression vectorDepositorInsertCD274 (CD274 Human)
UseLuciferaseTagsExpressionMammalianMutationN.B. There are two published SNPs in this region …PromoterAvailable sinceMarch 28, 2018AvailabilityAcademic Institutions and Nonprofits only -
pGL3 1 kb prom and exon1 fragment CD274
Plasmid#107006PurposeModified Luciferase expression vectorDepositorInsertCD274 (CD274 Human)
UseLuciferaseTagsExpressionMammalianMutationPromoterAvailable sinceMarch 23, 2018AvailabilityAcademic Institutions and Nonprofits only -
MLRV3:HRE-P53-MAPK/JNK-FOXO-TGFβ
Plasmid#178320PurposeMultiplex luciferase reporter vector, with luciferase reporters for the pathways HRE, P53, AP-1, FOXO and SMAD.DepositorInsertsHRE RedFirefly reporter
P53 FLuc reporter
AP-1 Renilla reporter
FOXO NLuc Reporter
SMAD GrRenilla reporter
UseLuciferase and Synthetic BiologyTagsExpressionMammalianMutationPromoterAvailable sinceJuly 20, 2022AvailabilityAcademic Institutions and Nonprofits only -
pGL3 2 kb prom. and exon 1 fragment CD274
Plasmid#107007PurposeModified Luciferase expression vectorDepositorInsertCD274 (CD274 Human)
UseLuciferaseTagsExpressionMammalianMutationPromoterAvailable sinceMarch 23, 2018AvailabilityAcademic Institutions and Nonprofits only -
Blimp1pGL3 (Human Blimp1 promoter in pGL3-basic)
Plasmid#40340DepositorInsertBlimp1 promoter (PRDM1 Human)
UseLuciferaseTagsLuciferaseExpressionMammalianMutationPromoterBlimp1Available sinceOct. 12, 2012AvailabilityAcademic Institutions and Nonprofits only -
p6xAP-1_RE
Plasmid#118054PurposeGBPart - Operator/DNA Response element - 6 copies of the AP-1 binding motifDepositorInsert6 copies of the AP-1 binding motif
UseSynthetic BiologyTagsExpressionMammalianMutationPromoterAvailable sinceDec. 16, 2019AvailabilityAcademic Institutions and Nonprofits only -
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hGR-Dx
Plasmid#133408Purposeoverexpression of a mutant human glucocorticoid receptor in mammalian cellsDepositorInsertNR3C1 (NR3C1 Human)
UseTagsExpressionMammalianMutationN454D, A458T, R460D, D462CPromoterAvailable sinceDec. 3, 2019AvailabilityAcademic Institutions and Nonprofits only -
ErbB-3-pGL3
Plasmid#60899Purposehuman ErbB-3 promoter reporter constructDepositorInsertErbB-3 promoter (ERBB3 Human)
UseLuciferaseTagsluciferaseExpressionMutationPromoterAvailable sinceNov. 19, 2014AvailabilityAcademic Institutions and Nonprofits only -
pmIL-6 -231
Plasmid#61287Purposedrives luciferase via mouse IL-6 promoter, truncated (-231)DepositorInsertTruncated IL-6 promoter
UseLuciferaseTagsExpressionMammalianMutationDeletion of 1046 nucleotides from the 5' end…PromoterIL-6 promoter (truncated)Available sinceMay 4, 2015AvailabilityAcademic Institutions and Nonprofits only -
pmIL-6 FL
Plasmid#61286Purposedrives luciferase from Wt mouse IL-6 promoter (full length)DepositorInsertIL-6 promoter (Il6 Mouse)
UseLuciferaseTagsExpressionMammalianMutationPromoterIL-6 full length promoterAvailable sinceMay 4, 2015AvailabilityAcademic Institutions and Nonprofits only -
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human MMP-2 promoter
Plasmid#53432Purposepromoter activity studyDepositorInsertMMP2 promoter (MMP2 Human)
UseLuciferaseTagsluciferaseExpressionMammalianMutationPromoterMMP2Available sinceJune 2, 2014AvailabilityAcademic Institutions and Nonprofits only -
pmIL-6 mut NF-kB
Plasmid#61293Purposedrives luciferase from mouse IL-6 promoter with mutation in NF-kB siteDepositorInsertIL-6 promoter (Il6 Mouse)
UseLuciferaseTagsExpressionMammalianMutationMutated NF-kB binding site from GTGGGATTTTCCCA to…PromoterIL-6 promoter with mutant NF-kB binding siteAvailable sinceMay 4, 2015AvailabilityAcademic Institutions and Nonprofits only -
pmIL-6 mut C/EBP
Plasmid#61291Purposedrives luciferase from mouse IL-6 promoter with mutant C/EBP (NF-IL-6) siteDepositorInsertIL-6 promoter (Il6 Mouse)
UseLuciferaseTagsExpressionMammalianMutationMutated C/EBP binding site from ACATTGTGCAATCT to…PromoterIL-6 promoter with mutant C/EBP binding siteAvailable sinceMay 4, 2015AvailabilityAcademic Institutions and Nonprofits only -
pGL3 Zscan4 promoter
Plasmid#69249PurposeLuciferase reporter for Dux4 activation of Zscan4 transcriptionDepositorInsertZscan4 (ZSCAN4 Human)
UseLuciferaseTagsExpressionMutationThe two single nucleotide mismatches found betwee…PromoterZscan4Available sinceSept. 21, 2015AvailabilityAcademic Institutions and Nonprofits only -
-227 hTF (mutant NF-kB)
Plasmid#15443DepositorInsertTissue factor promoter (F3 Human)
UseLuciferaseTagsExpressionMammalianMutationNF-kappaB binding domain mutatedPromoterAvailable sinceJuly 27, 2007AvailabilityAcademic Institutions and Nonprofits only -
p28-2iDP-puro
Plasmid#88893PurposeDual-intron DMD platform plasmid. Co-expresses DMD platform segment, firefly luciferase, puroR and mCherry. Plasmid carries phiC31 and Bxb1 attB sites.DepositorInsertsDual-intron DMD platform
luciferase
puromycin resistance enzyme
mCherry
UseTagsExpressionMammalianMutationTruncated version of the dystrophin protein (tran…PromoterAvailable sinceJan. 5, 2018AvailabilityAcademic Institutions and Nonprofits only