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We narrowed to 14,239 results for: cas9 genes

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Showing: 10401 - 10450 of 14239 results

  1. gTBEv4

    Plasmid
    #220620
    Purpose
    vector for encoding an engineered glycosylase-based thymine (T) base editor (gTBEv4) driven by EF1a promoter, guide RNAs compatible with SpCas9 driven by hU6, mCherry driven by CBh promoter
    Depositor
    Huawei Tong
    Article
    Tong et al Nat Commun. 2024 Jun 8;15(1):4897. doi:
    Insert
    nSpCas9(Nterm)-XTEN-hUNG2-XTEN-Cas9(Cterm)
    Expression
    Mammalian
    Mutation
    hUNG2(del1-88;Y156A,A214T,Q259A,Y284D), SpCas9(D1…
    Promoter
    hU6, EF1a
    Available Since
    June 21, 2024
    Availability
    Academic Institutions and Nonprofits only
    220620-plasmid-map-sequence-id-436970

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  6. pUC19-U6-[BsmBI_pegRNA_entry]-tevopreQ1-term (LM1138)

    Plasmid
    #223137
    Purpose
    pU6 entry plamid for cloning prime editor tevopreQ1 epegRNAs (requires BsmBI or Esp3I digest and ligation of duplexed oligos)
    Depositor
    Benjamin Kleinstiver
    Article
    Silverstein et al Nature. 2025 Apr 22. doi: 10.1038/s41586
    Insert
    etevopreQ1 entry plasmid backbone for epegRNA expression via human U6 promoter
    Use
    CRISPR
    Expression
    Mammalian
    Promoter
    U6
    Available Since
    April 23, 2025
    Availability
    Academic Institutions and Nonprofits only
    223137-plasmid-map-sequence-id-447707

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  10. pAAV-i53-DM

    Plasmid
    #92171
    Purpose
    recombinant adeno-associated viral plasmid for delivery and expression of ubiquitin variant that has reverted mutations L69P and V70L (i53-DM)
    Depositor
    Daniel Durocher
    Article
    Canny et al Nat Biotechnol. 2018 Jan;36(1):95-102. d
    Insert
    i53-DM
    Use
    AAV
    Tags
    FLAG
    Expression
    Mammalian
    Mutation
    UbvG08 with I44A, P69L, and L70V mutations and no…
    Promoter
    CMV
    Available Since
    July 13, 2017
    Availability
    Industry, Academic Institutions, and Nonprofits
    92171-plasmid-map-sequence-id-182616

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  19. PX459-gR2A_Hinge

    Plasmid
    #124811
    Purpose
    Vector for expression Cas9 with gRNA specific for rat IgG2a heavy chain locus. Use in combination with pHybr_r2a>Fab-srt-his plasmids to convert expression of hybridomas to Fab' fragments.
    Depositor
    Ferenc Scheeren, Martijn Verdoes
    Article
    van der Schoot et al Sci Adv. 2019 Aug 28;5(8):eaaw1822. doi:
    Insert
    Cas9 – gRNA_R2A_hinge
    Use
    CRISPR
    Tags
    3XFLAG and GFP
    Expression
    Bacterial and Mammalian
    Mutation
    R166H in PuroR (please see depositors comment bel…
    Promoter
    pUC
    Available Since
    Sept. 9, 2019
    Availability
    Academic Institutions and Nonprofits only
    124811-plasmid-map-sequence-id-243700

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  20. pMini-CMV-NLS-dead R-IscB_ADAR2dd-NES_T2A_mCherry (W98X)_U6-ωRNA

    Plasmid
    #246432
    Purpose
    All-in-one plasmid. Expresses R-IscB_ADAR2dd in mammalian cells for A-to-I RNA editing. Inactive mCherry included to assess A-to-I editing. Spacer included can direct mCherry fluorescence recovery.
    Depositor
    Ailong Ke
    Article
    Xu et al Cell. 2025 Aug 18:S0092-8674(25)00854-2.
    Inserts
    O.gue IscB with dead mutations (D60A, H269A) and delta-TID, fused to human ADAR2 deaminase domain
    mCherry
    ωRNA
    Tags
    HIV NES, SGGSSGGSSGSETPGTSESATPESSGGSSGGS linker …
    Expression
    Mammalian
    Mutation
    R-IscB: changed Aspartic Acid 60 to Alanine, chan…
    Promoter
    CMV and U6
    Available Since
    Nov. 13, 2025
    Availability
    Academic Institutions and Nonprofits only
    246432-plasmid-map-sequence-id-490908

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  21. MKC86_HBA1(tEPOR-2A-YFP)

    Plasmid
    #232405
    Purpose
    AAV production plasmid for tEPOR-2A-YFP vector from Fig. 2 that mediates HDR at HBA1 locus using HBA1-sg4 gRNA. HBA1 UTRs flank full tEPOR-2A-YFP cassette. Homology arms mediate full HBA1 replacement.
    Depositor
    Kyle Cromer, Matthew Porteus
    Article
    Luna et al Nat Biomed Eng. 2024 Dec;8(12):1540-1552
    Inserts
    Truncated Erythropoietin Receptor (EPOR Human)
    Hemoglobin Subunit Alpha 1 (HBA1 Human)
    Use
    AAV
    Expression
    Mammalian
    Available Since
    April 18, 2025
    Availability
    Academic Institutions and Nonprofits only
    232405-plasmid-map-sequence-id-462759

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  22. pSRG100 (germline optimized 3xGCN4 for C. elegans)

    Plasmid
    #246457
    Purpose
    Encodes germline optimized 3xGCN4 for C. elegans. Useful to make CRISPR/Cas9 repair templates for 3xGCN4 integration in a gene of interest. For SunTag live-imaging of translation or protein labelling.
    Depositor
    Suzan Ruijtenberg
    Insert
    3xGCN4 (GLO)
    Expression
    Worm
    Available Since
    Jan. 7, 2026
    Availability
    Academic Institutions and Nonprofits only
    246457-plasmid-map-sequence-id-496369

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  23. pSG1039-rA1-SaKKH_P2A_EGFP

    Plasmid
    #239462
    Purpose
    Cytosine base editor with codon-optimized S. aureus KKH Cas9 and rAPOBEC1 deaminase. EGFP can be used as a transfection marker.
    Depositor
    Alexis Komor
    Insert
    S.a. rA1 CBE
    Use
    CRISPR
    Tags
    EGFP
    Expression
    Mammalian
    Promoter
    CMV
    Available Since
    June 23, 2025
    Availability
    Academic Institutions and Nonprofits only
    239462-plasmid-map-sequence-id-476829

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  24. pX330.puro

    Plasmid
    #110403
    Purpose
    CRISPR/Cas9 vector with sgRNA expression and puromycin resistance
    Depositor
    Sandra Martha Gomes Dias
    Type
    Empty backbone
    Use
    CRISPR
    Expression
    Mammalian
    Promoter
    CBh
    Available Since
    Feb. 23, 2021
    Availability
    Academic Institutions and Nonprofits only
    110403-plasmid-map-sequence-id-213570

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  25. pEG302-SunTagng-22aa

    Plasmid
    #115345
    Purpose
    Encodes a SunTag CRISPR cas9 system that does not contain a guide RNA and therefore, does not target the TET1 catalytic domain to any specific region of the genome
    Depositor
    Steven Jacobsen
    Insert
    NOS_TET1CD_2xNLS_1xHA__sfGFP_scFv_UBQ10_INSULATOR_UBQ10_dCAS9_1xHA_3xNLS_10xGCN422aa_OCS
    Use
    CRISPR and Synthetic Biology
    Expression
    Plant
    Available Since
    Nov. 14, 2018
    Availability
    Academic Institutions and Nonprofits only
    115345-plasmid-map-sequence-id-222916

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  26. pCMV-ABE-P48R-UGI

    Plasmid
    #161817
    Purpose
    Expresses ABE-P48R-UGI in mammalian cells
    Depositor
    Sangsu Bae
    Insert
    bpNLS-TadA7.10(P48R)-32AA linker-hSpCas9n(D10A)-10AA linker-UGI-10AA linker-UGI-bpNLS-P2A-EGFP-NLS
    Use
    CRISPR
    Expression
    Mammalian
    Mutation
    D10A in S. pyogenes Cas9, TadA mutations describe…
    Available Since
    Jan. 4, 2021
    Availability
    Academic Institutions and Nonprofits only
    161817-plasmid-map-sequence-id-320651

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  27. pTFAM.1.0-gDNA

    Plasmid
    #132443
    Purpose
    CRISPR/Cas9 plasmid to create GFP fusion proteins
    Depositor
    Kevin White
    Insert
    TFAM (TFAM Human)
    Use
    CRISPR
    Available Since
    Dec. 17, 2019
    Availability
    Academic Institutions and Nonprofits only
    132443-plasmid-map-sequence-id-266777

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  29. pZBTB12.1.0-gDNA

    Plasmid
    #113769
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZBTB12
    Depositor
    Kevin White
    Insert
    ZBTB12 (ZBTB12 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 11, 2018
    Availability
    Academic Institutions and Nonprofits only
    113769-plasmid-map-sequence-id-230555

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  30. pSPDEF.1.0-gDNA

    Plasmid
    #113796
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor SPDEF
    Depositor
    Kevin White
    Insert
    SPDEF (SPDEF Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 11, 2018
    Availability
    Academic Institutions and Nonprofits only
    113796-plasmid-map-sequence-id-230613

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  31. pZBTB17.1.0-gDNA

    Plasmid
    #112483
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZBTB17
    Depositor
    Kevin White
    Insert
    ZBTB17 (ZBTB17 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 10, 2018
    Availability
    Academic Institutions and Nonprofits only
    112483-plasmid-map-sequence-id-230520

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  32. pMLX.1.0-gDNA

    Plasmid
    #112466
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor MLX
    Depositor
    Kevin White
    Insert
    MLX (MLX Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 10, 2018
    Availability
    Academic Institutions and Nonprofits only
    112466-plasmid-map-sequence-id-230496

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  34. pTFCP2.1.0-gDNA

    Plasmid
    #112404
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor TFCP2
    Depositor
    Kevin White
    Insert
    TFCP2 (TFCP2 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 6, 2018
    Availability
    Academic Institutions and Nonprofits only
    112404-plasmid-map-sequence-id-230259

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  35. pX330.orup

    Plasmid
    #110404
    Purpose
    CRISPR/Cas9 vector with sgRNA expression and puromycin resistance
    Depositor
    Sandra Martha Gomes Dias
    Type
    Empty backbone
    Use
    CRISPR
    Expression
    Mammalian
    Promoter
    CBh
    Available Since
    Feb. 23, 2021
    Availability
    Academic Institutions and Nonprofits only
    110404-plasmid-map-sequence-id-307700

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  36. pARID4B.1.0-gDNA

    Plasmid
    #132436
    Purpose
    CRISPR/Cas9 plasmid to create GFP fusion proteins
    Depositor
    Kevin White
    Insert
    ARID4B (ARID4B Human)
    Use
    CRISPR
    Available Since
    July 10, 2020
    Availability
    Academic Institutions and Nonprofits only
    132436-plasmid-map-sequence-id-266218

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  37. pCSRNP3.1.0-gDNA

    Plasmid
    #132472
    Purpose
    CRISPR/Cas9 plasmid to create GFP fusion proteins
    Depositor
    Kevin White
    Insert
    CSRNP3 (CSRNP3 Human)
    Use
    CRISPR
    Available Since
    Dec. 23, 2019
    Availability
    Academic Institutions and Nonprofits only
    132472-plasmid-map-sequence-id-267179

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  38. pHOXB6.1.0-gDNA

    Plasmid
    #132458
    Purpose
    CRISPR/Cas9 plasmid to create GFP fusion proteins
    Depositor
    Kevin White
    Insert
    HOXB6 (HOXB6 Human)
    Use
    CRISPR
    Available Since
    Dec. 19, 2019
    Availability
    Academic Institutions and Nonprofits only
    132458-plasmid-map-sequence-id-266992

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  39. pGTF2I.1.0-gDNA

    Plasmid
    #132452
    Purpose
    CRISPR/Cas9 plasmid to create GFP fusion proteins
    Depositor
    Kevin White
    Insert
    GTF2I (GTF2I Human)
    Use
    CRISPR
    Available Since
    Dec. 18, 2019
    Availability
    Academic Institutions and Nonprofits only
    132452-plasmid-map-sequence-id-266821

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  40. pHMG20B.1.0-gDNA

    Plasmid
    #132449
    Purpose
    CRISPR/Cas9 plasmid to create GFP fusion proteins
    Depositor
    Kevin White
    Insert
    HMG20B (HMG20B Human)
    Use
    CRISPR
    Available Since
    Dec. 17, 2019
    Availability
    Academic Institutions and Nonprofits only
    132449-plasmid-map-sequence-id-266806

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  41. pMECOM.1.0-gDNA

    Plasmid
    #132445
    Purpose
    CRISPR/Cas9 plasmid to create GFP fusion proteins
    Depositor
    Kevin White
    Insert
    MECOM (MECOM Human)
    Use
    CRISPR
    Available Since
    Dec. 17, 2019
    Availability
    Academic Institutions and Nonprofits only
    132445-plasmid-map-sequence-id-266786

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  42. pKLF10.1.0-gDNA

    Plasmid
    #132433
    Purpose
    CRISPR/Cas9 plasmid to create GFP fusion proteins
    Depositor
    Kevin White
    Insert
    KLF10 (KLF10 Human)
    Use
    CRISPR
    Available Since
    Dec. 11, 2019
    Availability
    Academic Institutions and Nonprofits only
    132433-plasmid-map-sequence-id-266215

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  43. pMSX2.1.0-gDNA

    Plasmid
    #113793
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor MSX2
    Depositor
    Kevin White
    Insert
    MSX2 (MSX2 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    April 11, 2019
    Availability
    Academic Institutions and Nonprofits only
    113793-plasmid-map-sequence-id-241255

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  44. pTOX2.1.0-gDNA

    Plasmid
    #113787
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor TOX2
    Depositor
    Kevin White
    Insert
    TOX2 (TOX2 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 11, 2018
    Availability
    Academic Institutions and Nonprofits only
    113787-plasmid-map-sequence-id-230586

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  45. pTSHZ2.1.0-gDNA

    Plasmid
    #113778
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor TSHZ2
    Depositor
    Kevin White
    Insert
    TSHZ2 (TSHZ2 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 11, 2018
    Availability
    Academic Institutions and Nonprofits only
    113778-plasmid-map-sequence-id-230569

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  46. pTCFL5.1.0-gDNA

    Plasmid
    #113775
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor TCFL5
    Depositor
    Kevin White
    Insert
    TCFL5 (TCFL5 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 11, 2018
    Availability
    Academic Institutions and Nonprofits only
    113775-plasmid-map-sequence-id-230564

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  47. pZNF444.1.0-gDNA

    Plasmid
    #112482
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZNF444
    Depositor
    Kevin White
    Insert
    ZNF444 (ZNF444 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 10, 2018
    Availability
    Academic Institutions and Nonprofits only
    112482-plasmid-map-sequence-id-230518

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  48. pZNF211.1.0-gDNA

    Plasmid
    #112478
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZNF211
    Depositor
    Kevin White
    Insert
    ZNF211 (ZNF211 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 10, 2018
    Availability
    Academic Institutions and Nonprofits only
    112478-plasmid-map-sequence-id-230513

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  49. pZKSCAN4.1.0-gDNA

    Plasmid
    #112465
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZKSCAN4
    Depositor
    Kevin White
    Insert
    ZKSCAN4 (ZKSCAN4 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 10, 2018
    Availability
    Academic Institutions and Nonprofits only
    112465-plasmid-map-sequence-id-230495

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  50. pNR2F6.1.0-gDNA

    Plasmid
    #112456
    Purpose
    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor NR2F6
    Depositor
    Kevin White
    Insert
    NR2F6 (NR2F6 Human)
    Use
    CRISPR
    Expression
    Mammalian
    Available Since
    Dec. 10, 2018
    Availability
    Academic Institutions and Nonprofits only
    112456-plasmid-map-sequence-id-230473

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Showing: 10401 - 10450 of 14239 results